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Article: Pyogenic liver abscess: Retrospective analysis of 80 cases over a 10-year period

TitlePyogenic liver abscess: Retrospective analysis of 80 cases over a 10-year period
Authors
Issue Date2002
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH
Citation
Journal Of Gastroenterology And Hepatology, 2002, v. 17 n. 9, p. 1001-1007 How to Cite?
AbstractBackground: A total of 80 patients with pyogenic liver abscess managed at a single institution over a 10-year period were studied. Methods: The clinical features, laboratory, imaging, and microbiologic findings, management strategy, and final outcome were studied. Results: Fever and chills, leucocytosis and elevated alkaline phosphatase were the most common clinical and laboratory findings. Forty-one percent of patients were diabetic and 61% had biliary pathology. Systemic antibiotics and image-guided aspiration had a success rate of 94%. By multiple logistic regression analysis, malignancy on presentation (P=0.011) was an independent risk factor associated with mortality. A past history of endoscopic sphincterotomy was an independent factor associated with resolution of liver abscess within 6 weeks (P=0.03). Conclusion: Pyrexia, leucocytosis, elevated alkaline phosphatase, presence of diabetes, and underlying biliary pathology are common clinical and laboratory findings in patients with pyogenic liver abscess. Malignancy was associated with a poor outcome. Previous endoscopic sphincterotomy was a good prognostic factor for early resolution. © 2002 Blackwell Publishing Asia Pty Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/162608
ISSN
2015 Impact Factor: 3.322
2015 SCImago Journal Rankings: 1.190
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, WMen_US
dc.contributor.authorWong, BCYen_US
dc.contributor.authorHui, CKen_US
dc.contributor.authorNg, Men_US
dc.contributor.authorLai, KCen_US
dc.contributor.authorTso, WKen_US
dc.contributor.authorLam, SKen_US
dc.contributor.authorLai, CLen_US
dc.date.accessioned2012-09-05T05:21:38Z-
dc.date.available2012-09-05T05:21:38Z-
dc.date.issued2002en_US
dc.identifier.citationJournal Of Gastroenterology And Hepatology, 2002, v. 17 n. 9, p. 1001-1007en_US
dc.identifier.issn0815-9319en_US
dc.identifier.urihttp://hdl.handle.net/10722/162608-
dc.description.abstractBackground: A total of 80 patients with pyogenic liver abscess managed at a single institution over a 10-year period were studied. Methods: The clinical features, laboratory, imaging, and microbiologic findings, management strategy, and final outcome were studied. Results: Fever and chills, leucocytosis and elevated alkaline phosphatase were the most common clinical and laboratory findings. Forty-one percent of patients were diabetic and 61% had biliary pathology. Systemic antibiotics and image-guided aspiration had a success rate of 94%. By multiple logistic regression analysis, malignancy on presentation (P=0.011) was an independent risk factor associated with mortality. A past history of endoscopic sphincterotomy was an independent factor associated with resolution of liver abscess within 6 weeks (P=0.03). Conclusion: Pyrexia, leucocytosis, elevated alkaline phosphatase, presence of diabetes, and underlying biliary pathology are common clinical and laboratory findings in patients with pyogenic liver abscess. Malignancy was associated with a poor outcome. Previous endoscopic sphincterotomy was a good prognostic factor for early resolution. © 2002 Blackwell Publishing Asia Pty Ltd.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGHen_US
dc.relation.ispartofJournal of Gastroenterology and Hepatologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAnti-Bacterial Agents - Therapeutic Useen_US
dc.subject.meshComorbidityen_US
dc.subject.meshDiabetes Complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGram-Negative Bacterial Infections - Microbiology - Mortality - Pathology - Therapyen_US
dc.subject.meshGram-Positive Bacterial Infections - Microbiology - Mortality - Pathology - Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Abscess - Microbiology - Mortality - Pathology - Therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshTreatment Outcomeen_US
dc.titlePyogenic liver abscess: Retrospective analysis of 80 cases over a 10-year perioden_US
dc.typeArticleen_US
dc.identifier.emailWong, BCY:bcywong@hku.hken_US
dc.identifier.emailLai, CL:hrmelcl@hku.hken_US
dc.identifier.authorityWong, BCY=rp00429en_US
dc.identifier.authorityLai, CL=rp00314en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1046/j.1440-1746.2002.02787.xen_US
dc.identifier.pmid12167122-
dc.identifier.scopuseid_2-s2.0-0036378413en_US
dc.identifier.hkuros80567-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036378413&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume17en_US
dc.identifier.issue9en_US
dc.identifier.spage1001en_US
dc.identifier.epage1007en_US
dc.identifier.isiWOS:000179400700012-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridWong, WM=36847934700en_US
dc.identifier.scopusauthoridWong, BCY=7402023340en_US
dc.identifier.scopusauthoridHui, CK=7202876933en_US
dc.identifier.scopusauthoridNg, M=7202076310en_US
dc.identifier.scopusauthoridLai, KC=7402135595en_US
dc.identifier.scopusauthoridTso, WK=7006905486en_US
dc.identifier.scopusauthoridLam, SK=7402279473en_US
dc.identifier.scopusauthoridLai, CL=7403086396en_US

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