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Article: Relationship between adequacy of dialysis and nutritional status, and their impact on patient survival on CAPD in Hong Kong

TitleRelationship between adequacy of dialysis and nutritional status, and their impact on patient survival on CAPD in Hong Kong
Authors
Issue Date2001
PublisherMultimed, Inc. The Journal's web site is located at http://pdiconnect.com
Citation
Peritoneal Dialysis International, 2001, v. 21 n. 5, p. 441-447 How to Cite?
Abstract◆ Objective: Superior patient survival on continuous ambulatory peritoneal dialysis (CAPD) with 3 × 2-L exchanges has been reported from Hong Kong. This study examined the relationship between indices of dialysis adequacy and nutrition and patient survival on CAPD in Hong Kong. ◆ Design: A cross-sectional study on prevalent CAPD patients. Patients were assessed for indices of dialysis adequacy and nutritional status with a composite nutritional index (CNI). Patients were then followed for 24 months. Survival data were analyzed according to adequacy indices and nutritional status. ◆ Setting: All prevalent CAPD patients in nine dialysis centers in Hong Kong as of 1 April 1996. ◆ Main Outcome Measure: Mortality. ◆ Results: 937 patients were assessed: 68.2% were using 3 × 2-L exchanges per day; mean age was 54.6 ± 13 years. Mean total Kt/V was 1.83 ± 0.42 and total creatinine clearance was 55.6 ± 19.5 L/week/1.73 m 2. 19% of patients were moderately to severely malnourished according to the CNI. There was no significant correlation between indices of adequacy and serum albumin or CNI. The 1- and 2-year patient survival from the time of assessment was 90.9% and 79.8%. There was a trend toward better survival in patients with Kt/V greater than 2.0, but it was not statistically significant. Peritoneal Kt/V did not impact survival in anuric patients. Malnourished patients had poorer survival than patients who were better nourished (p = 0.0259). After adjusting for age and diabetes, CNI was predictive of mortality but Kt/V and creatinine clearance were not. ◆ Conclusions: This study demonstrates the importance of nutritional status over adequacy indices in predicting patient survival. There was a lack of correlation between nutritional status and conventional indices of dialysis adequacy.
Persistent Identifierhttp://hdl.handle.net/10722/162465
ISSN
2015 Impact Factor: 1.298
2015 SCImago Journal Rankings: 0.683
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLo, WKen_US
dc.contributor.authorTong, KLen_US
dc.contributor.authorLi, CSen_US
dc.contributor.authorChan, TMen_US
dc.contributor.authorWong, AKMen_US
dc.contributor.authorHo, YWen_US
dc.contributor.authorCheung, KOen_US
dc.contributor.authorKwan, THen_US
dc.contributor.authorWong, KSen_US
dc.contributor.authorNg, FSKen_US
dc.contributor.authorCheng, IKPen_US
dc.date.accessioned2012-09-05T05:20:13Z-
dc.date.available2012-09-05T05:20:13Z-
dc.date.issued2001en_US
dc.identifier.citationPeritoneal Dialysis International, 2001, v. 21 n. 5, p. 441-447en_US
dc.identifier.issn0896-8608en_US
dc.identifier.urihttp://hdl.handle.net/10722/162465-
dc.description.abstract◆ Objective: Superior patient survival on continuous ambulatory peritoneal dialysis (CAPD) with 3 × 2-L exchanges has been reported from Hong Kong. This study examined the relationship between indices of dialysis adequacy and nutrition and patient survival on CAPD in Hong Kong. ◆ Design: A cross-sectional study on prevalent CAPD patients. Patients were assessed for indices of dialysis adequacy and nutritional status with a composite nutritional index (CNI). Patients were then followed for 24 months. Survival data were analyzed according to adequacy indices and nutritional status. ◆ Setting: All prevalent CAPD patients in nine dialysis centers in Hong Kong as of 1 April 1996. ◆ Main Outcome Measure: Mortality. ◆ Results: 937 patients were assessed: 68.2% were using 3 × 2-L exchanges per day; mean age was 54.6 ± 13 years. Mean total Kt/V was 1.83 ± 0.42 and total creatinine clearance was 55.6 ± 19.5 L/week/1.73 m 2. 19% of patients were moderately to severely malnourished according to the CNI. There was no significant correlation between indices of adequacy and serum albumin or CNI. The 1- and 2-year patient survival from the time of assessment was 90.9% and 79.8%. There was a trend toward better survival in patients with Kt/V greater than 2.0, but it was not statistically significant. Peritoneal Kt/V did not impact survival in anuric patients. Malnourished patients had poorer survival than patients who were better nourished (p = 0.0259). After adjusting for age and diabetes, CNI was predictive of mortality but Kt/V and creatinine clearance were not. ◆ Conclusions: This study demonstrates the importance of nutritional status over adequacy indices in predicting patient survival. There was a lack of correlation between nutritional status and conventional indices of dialysis adequacy.en_US
dc.languageengen_US
dc.publisherMultimed, Inc. The Journal's web site is located at http://pdiconnect.comen_US
dc.relation.ispartofPeritoneal Dialysis Internationalen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBody Mass Indexen_US
dc.subject.meshBody Weighten_US
dc.subject.meshCreatinine - Metabolism - Urineen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Failure, Chronic - Metabolism - Mortality - Therapyen_US
dc.subject.meshLife Tablesen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNutritional Statusen_US
dc.subject.meshPeritoneal Dialysis, Continuous Ambulatory - Mortality - Statistics & Numerical Dataen_US
dc.subject.meshProportional Hazards Modelsen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSerum Albumin - Metabolismen_US
dc.subject.meshSurvival Rateen_US
dc.titleRelationship between adequacy of dialysis and nutritional status, and their impact on patient survival on CAPD in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailChan, TM:dtmchan@hku.hken_US
dc.identifier.authorityChan, TM=rp00394en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid11757826-
dc.identifier.scopuseid_2-s2.0-0034781201en_US
dc.identifier.hkuros67554-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034781201&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume21en_US
dc.identifier.issue5en_US
dc.identifier.spage441en_US
dc.identifier.epage447en_US
dc.identifier.isiWOS:000171842400003-
dc.publisher.placeCanadaen_US
dc.identifier.scopusauthoridLo, WK=7201502414en_US
dc.identifier.scopusauthoridTong, KL=7102473456en_US
dc.identifier.scopusauthoridLi, CS=36068236000en_US
dc.identifier.scopusauthoridChan, TM=7402687700en_US
dc.identifier.scopusauthoridWong, AKM=7403147057en_US
dc.identifier.scopusauthoridHo, YW=7402555047en_US
dc.identifier.scopusauthoridCheung, KO=7402406558en_US
dc.identifier.scopusauthoridKwan, TH=7102388102en_US
dc.identifier.scopusauthoridWong, KS=8079870700en_US
dc.identifier.scopusauthoridNg, FSK=7103125634en_US
dc.identifier.scopusauthoridCheng, IKP=7102537483en_US

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