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Article: Value of intra-arterial calcium stimulated venous sampling for regionalization of pancreatic insulinomas

TitleValue of intra-arterial calcium stimulated venous sampling for regionalization of pancreatic insulinomas
Authors
Issue Date2000
PublisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/surg
Citation
Surgery, 2000, v. 128 n. 6, p. 903-909 How to Cite?
AbstractBackground. Intra-arterial calcium stimulation with hepatic venous sampling (ASVS) for insulin gradients has been reported to be the most sensitive preoperative localizing technique for insulinomas. We reviewed our experience with ASVS to localize and guide the treatment of insulinomas over the past decade. Methods. Eighteen patients who underwent ASVS before surgical exploration for insulinoma were studied. The accuracy of ASVS was compared with intraoperative findings and other localizing studies. Results. There were no complications arising from the procedures. A more than 2-fold step-up in insulin level 30 to 60 seconds after injection to at least 1 feeding artery was observed in 16 patients. Fourteen of the 16 solitary tumors (87.5%) were correctly located; 100% (6/6 tumors) at the head and 80% (8/10 tumors) at the body/tail. The overall accuracy of this test was 89%, compared with 11%, 33%, 38%, and 63% of ultrasonography, computed tomography, magnetic resonance imaging, and endoscopic ultrasonography, respectively. Six enucleations and 10 distal resections were performed, which included 2 laparoscopic procedures. The combination of intraoperative ultrasonography with preoperative ASVS identified all tumors. Conclusions. ASVS is the most accurate preoperative localization tool for the localization of insulinomas and, in combination with intraoperative ultrasonography, can enhance surgical success.
Persistent Identifierhttp://hdl.handle.net/10722/162370
ISSN
2015 Impact Factor: 3.309
2015 SCImago Journal Rankings: 1.620
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLo, CYen_HK
dc.contributor.authorChan, FLen_HK
dc.contributor.authorTam, SCFen_HK
dc.contributor.authorCheng, PWen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorLam, KSLen_HK
dc.contributor.authorInabnet, Ben_HK
dc.contributor.authorProye, Cen_HK
dc.date.accessioned2012-09-05T05:19:20Z-
dc.date.available2012-09-05T05:19:20Z-
dc.date.issued2000en_HK
dc.identifier.citationSurgery, 2000, v. 128 n. 6, p. 903-909en_HK
dc.identifier.issn0039-6060en_HK
dc.identifier.urihttp://hdl.handle.net/10722/162370-
dc.description.abstractBackground. Intra-arterial calcium stimulation with hepatic venous sampling (ASVS) for insulin gradients has been reported to be the most sensitive preoperative localizing technique for insulinomas. We reviewed our experience with ASVS to localize and guide the treatment of insulinomas over the past decade. Methods. Eighteen patients who underwent ASVS before surgical exploration for insulinoma were studied. The accuracy of ASVS was compared with intraoperative findings and other localizing studies. Results. There were no complications arising from the procedures. A more than 2-fold step-up in insulin level 30 to 60 seconds after injection to at least 1 feeding artery was observed in 16 patients. Fourteen of the 16 solitary tumors (87.5%) were correctly located; 100% (6/6 tumors) at the head and 80% (8/10 tumors) at the body/tail. The overall accuracy of this test was 89%, compared with 11%, 33%, 38%, and 63% of ultrasonography, computed tomography, magnetic resonance imaging, and endoscopic ultrasonography, respectively. Six enucleations and 10 distal resections were performed, which included 2 laparoscopic procedures. The combination of intraoperative ultrasonography with preoperative ASVS identified all tumors. Conclusions. ASVS is the most accurate preoperative localization tool for the localization of insulinomas and, in combination with intraoperative ultrasonography, can enhance surgical success.en_HK
dc.languageengen_US
dc.publisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/surgen_HK
dc.relation.ispartofSurgeryen_HK
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCalcium - Diagnostic Useen_US
dc.subject.meshCost-Benefit Analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatic Veinsen_US
dc.subject.meshHumansen_US
dc.subject.meshInsulin - Blooden_US
dc.subject.meshInsulinoma - Diagnosis - Surgeryen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMultiple Endocrine Neoplasia Type 1 - Surgeryen_US
dc.subject.meshPancreatic Neoplasms - Diagnosis - Surgeryen_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshSplenic Arteryen_US
dc.titleValue of intra-arterial calcium stimulated venous sampling for regionalization of pancreatic insulinomasen_HK
dc.typeArticleen_HK
dc.identifier.emailLo, CY: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.emailLam, KSL: ksllam@hku.hken_HK
dc.identifier.authorityLo, CY=rp00412en_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.identifier.authorityLam, KSL=rp00343en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1067/msy.2000.109729-
dc.identifier.pmid11114622-
dc.identifier.scopuseid_2-s2.0-0033665966en_HK
dc.identifier.hkuros57770-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033665966&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume128en_HK
dc.identifier.issue6en_HK
dc.identifier.spage903en_HK
dc.identifier.epage909en_HK
dc.identifier.isiWOS:000165776000008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLo, CY=7401771672en_HK
dc.identifier.scopusauthoridChan, FL=7202586444en_HK
dc.identifier.scopusauthoridTam, SCF=7202037323en_HK
dc.identifier.scopusauthoridCheng, PW=7401618753en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridLam, KSL=8082870600en_HK
dc.identifier.scopusauthoridInabnet, B=6602424950en_HK
dc.identifier.scopusauthoridProye, C=7102163183en_HK

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