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Article: Venous sampling: its role in localization of endocrine tumours.

TitleVenous sampling: its role in localization of endocrine tumours.
Authors
Issue Date1993
PublisherAcademy of Medicine Singapore. The Journal's web site is located at http://www.annals.edu.sg
Citation
Annals Of The Academy Of Medicine Singapore, 1993, v. 22 n. 5, p. 707-713 How to Cite?
AbstractDespite recent instrumentation advancement in morphologic imaging, venous sampling remains a sensitive physiological investigation for functional localization of hormonal hypersecretion. The test requires technical expertise and reliable laboratory support, and should be selectively applied to address individual clinical problems in coordination with other imaging modalities. Depending on the venous anatomy, sampling may achieve regional localization or lateralization of the endocrine tumour. Adrenal venous sampling serves to lateralize functioning tumour, and to differentiate it from hyperplasia. Inferior petrosal sinus sampling confirms pituitary Cushing's disease and lateralizes the adenoma. Systemic venous sampling identifies the site of ectopic hormonal secretion. In the localization of pancreatic islet cell tumours, the test is further enhanced by sampling after intraarterial injection of hormonal secretagogue. The experience of venous sampling in a regional referral hospital is discussed, including the patient selection, its technical details, pitfalls and effectiveness in achieving tumour localization for patient management.
Persistent Identifierhttp://hdl.handle.net/10722/162014
ISSN
2015 Impact Factor: 1.041
2015 SCImago Journal Rankings: 0.425

 

DC FieldValueLanguage
dc.contributor.authorChan, FLen_US
dc.contributor.authorLam, KSen_US
dc.date.accessioned2012-09-05T05:16:41Z-
dc.date.available2012-09-05T05:16:41Z-
dc.date.issued1993en_US
dc.identifier.citationAnnals Of The Academy Of Medicine Singapore, 1993, v. 22 n. 5, p. 707-713en_US
dc.identifier.issn0304-4602en_US
dc.identifier.urihttp://hdl.handle.net/10722/162014-
dc.description.abstractDespite recent instrumentation advancement in morphologic imaging, venous sampling remains a sensitive physiological investigation for functional localization of hormonal hypersecretion. The test requires technical expertise and reliable laboratory support, and should be selectively applied to address individual clinical problems in coordination with other imaging modalities. Depending on the venous anatomy, sampling may achieve regional localization or lateralization of the endocrine tumour. Adrenal venous sampling serves to lateralize functioning tumour, and to differentiate it from hyperplasia. Inferior petrosal sinus sampling confirms pituitary Cushing's disease and lateralizes the adenoma. Systemic venous sampling identifies the site of ectopic hormonal secretion. In the localization of pancreatic islet cell tumours, the test is further enhanced by sampling after intraarterial injection of hormonal secretagogue. The experience of venous sampling in a regional referral hospital is discussed, including the patient selection, its technical details, pitfalls and effectiveness in achieving tumour localization for patient management.en_US
dc.languageengen_US
dc.publisherAcademy of Medicine Singapore. The Journal's web site is located at http://www.annals.edu.sgen_US
dc.relation.ispartofAnnals of the Academy of Medicine Singaporeen_US
dc.subject.meshAdrenal Gland Neoplasms - Diagnosisen_US
dc.subject.meshAdrenal Glands - Blood Supplyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBlood Specimen Collection - Methodsen_US
dc.subject.meshEndocrine Gland Neoplasms - Blood - Diagnosis - Secretionen_US
dc.subject.meshHepatic Veinsen_US
dc.subject.meshHormones, Ectopic - Blooden_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPancreatic Neoplasms - Diagnosisen_US
dc.subject.meshParaneoplastic Endocrine Syndromes - Diagnosisen_US
dc.subject.meshPetrosal Sinus Samplingen_US
dc.subject.meshPituitary Neoplasms - Diagnosisen_US
dc.subject.meshPortal Veinen_US
dc.subject.meshRadiography, Interventionalen_US
dc.subject.meshVeinsen_US
dc.titleVenous sampling: its role in localization of endocrine tumours.en_US
dc.typeArticleen_US
dc.identifier.emailLam, KS:ksllam@hku.hken_US
dc.identifier.authorityLam, KS=rp00343en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8267350-
dc.identifier.scopuseid_2-s2.0-0027655524en_US
dc.identifier.volume22en_US
dc.identifier.issue5en_US
dc.identifier.spage707en_US
dc.identifier.epage713en_US
dc.publisher.placeSingaporeen_US
dc.identifier.scopusauthoridChan, FL=7202586444en_US
dc.identifier.scopusauthoridLam, KS=8082870600en_US

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