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Article: A review of clinicopathologic features of pheochromocytomas in Hong Kong Chinese

TitleA review of clinicopathologic features of pheochromocytomas in Hong Kong Chinese
Authors
KeywordsAdrenal glands
Chromogranin
Immunohistochemistry
Neuron-specific enolase
Pheochromocytoma
Synaptophysin
Issue Date1993
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejso
Citation
European Journal Of Surgical Oncology, 1993, v. 19 n. 5, p. 421-427 How to Cite?
AbstractTwenty-two Chinese patients with pheochromocytomas incuding 18 surgical and four autopsy cases were reported. The incidence at autopsy was 0.048%. The tumours were most common in the sixth and the fourth decades in males and females respectively. There was no sex predilection. The incidence of bilaterality was 4.5% and the tumours were more common on the right side. 9.1% of the the tumours were malignant and they were larger than their benign counterparts. Solid and diffuse pattern and mixed pattern were the most common histologic patterns. Minor histological features included hyaline globules (64%) nuclear pseudo-inclusions (55%) lipid degeneration (4.5%) and peri-adrenal brown fat (18%). All of them were strongly positive for the three pan-neuroendocrine markers (neuron-specific enolase synaptophysin and chromogranin) confirming the usefulness of these markers in diagnosing pheochromocytoma.
Persistent Identifierhttp://hdl.handle.net/10722/161987
ISSN
2023 Impact Factor: 3.5
2023 SCImago Journal Rankings: 1.164

 

DC FieldValueLanguage
dc.contributor.authorLam, KYen_US
dc.contributor.authorChan, ACLen_US
dc.contributor.authorWong, WMen_US
dc.contributor.authorLam, KSLen_US
dc.date.accessioned2012-09-05T05:16:29Z-
dc.date.available2012-09-05T05:16:29Z-
dc.date.issued1993en_US
dc.identifier.citationEuropean Journal Of Surgical Oncology, 1993, v. 19 n. 5, p. 421-427en_US
dc.identifier.issn0748-7983en_US
dc.identifier.urihttp://hdl.handle.net/10722/161987-
dc.description.abstractTwenty-two Chinese patients with pheochromocytomas incuding 18 surgical and four autopsy cases were reported. The incidence at autopsy was 0.048%. The tumours were most common in the sixth and the fourth decades in males and females respectively. There was no sex predilection. The incidence of bilaterality was 4.5% and the tumours were more common on the right side. 9.1% of the the tumours were malignant and they were larger than their benign counterparts. Solid and diffuse pattern and mixed pattern were the most common histologic patterns. Minor histological features included hyaline globules (64%) nuclear pseudo-inclusions (55%) lipid degeneration (4.5%) and peri-adrenal brown fat (18%). All of them were strongly positive for the three pan-neuroendocrine markers (neuron-specific enolase synaptophysin and chromogranin) confirming the usefulness of these markers in diagnosing pheochromocytoma.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejsoen_US
dc.relation.ispartofEuropean Journal of Surgical Oncologyen_US
dc.subjectAdrenal glands-
dc.subjectChromogranin-
dc.subjectImmunohistochemistry-
dc.subjectNeuron-specific enolase-
dc.subjectPheochromocytoma-
dc.subjectSynaptophysin-
dc.subject.meshAdolescenten_US
dc.subject.meshAdrenal Gland Neoplasms - Chemistry - Ethnology - Pathology - Physiopathologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshChromogranins - Analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPheochromocytoma - Chemistry - Ethnology - Pathology - Physiopathologyen_US
dc.subject.meshPhosphopyruvate Hydratase - Analysisen_US
dc.subject.meshSynaptophysin - Analysisen_US
dc.titleA review of clinicopathologic features of pheochromocytomas in Hong Kong Chineseen_US
dc.typeArticleen_US
dc.identifier.emailLam, KSL:ksllam@hku.hken_US
dc.identifier.authorityLam, KSL=rp00343en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8405477-
dc.identifier.scopuseid_2-s2.0-0027369331en_US
dc.identifier.volume19en_US
dc.identifier.issue5en_US
dc.identifier.spage421en_US
dc.identifier.epage427en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLam, KY=7403657165en_US
dc.identifier.scopusauthoridChan, ACL=16047349300en_US
dc.identifier.scopusauthoridWong, WM=7403972413en_US
dc.identifier.scopusauthoridLam, KSL=8082870600en_US
dc.identifier.issnl0748-7983-

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