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Article: Hepatitis C in renal transplant recipients

TitleHepatitis C in renal transplant recipients
Authors
Issue Date1991
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.transplantjournal.com
Citation
Transplantation, 1991, v. 52 n. 5, p. 810-813 How to Cite?
AbstractSera from 130 renal transplant recipients were tested for antibody to hepatitis C virus (anti-HCV). Anti-HCV was detected in 6.2% of patients: 15.4% of patients who had maintenance hemodialysis (HD) and 2.2% of those who had continuous ambulatory peritoneal dialysis (CAPD) before transplantation (P<0.05). The similarity in prevalence of anti-HCV with patients currently on dialysis and the absence of transfusion during posttransplant follow-up suggest that most patients acquired HCV infection through transfusion during dialysis. The proportion of anti-HCV-positive patients who had one or more episodes of elevation in serum transaminase level was similar to that of hepatitis B surface antigen (HBsAg)-positive patients, 75% vs. 72.2%. However, anti-HCV was only detected in 25% of HBsAg-negative patients who had recurrent elevations in serum transaminase level. It is not clear whether the low prevalence of anti-HCV in these patients is related to the presence of other non-A, non-B hepatitis virus (es) or a decrease in titer of anti-HCV secondary to immunosuppression posttransplantation.
Persistent Identifierhttp://hdl.handle.net/10722/161860
ISSN
2015 Impact Factor: 3.69
2015 SCImago Journal Rankings: 1.699
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, TMen_US
dc.contributor.authorLok, ASFen_US
dc.contributor.authorCheng, IKPen_US
dc.date.accessioned2012-09-05T05:15:34Z-
dc.date.available2012-09-05T05:15:34Z-
dc.date.issued1991en_US
dc.identifier.citationTransplantation, 1991, v. 52 n. 5, p. 810-813en_US
dc.identifier.issn0041-1337en_US
dc.identifier.urihttp://hdl.handle.net/10722/161860-
dc.description.abstractSera from 130 renal transplant recipients were tested for antibody to hepatitis C virus (anti-HCV). Anti-HCV was detected in 6.2% of patients: 15.4% of patients who had maintenance hemodialysis (HD) and 2.2% of those who had continuous ambulatory peritoneal dialysis (CAPD) before transplantation (P<0.05). The similarity in prevalence of anti-HCV with patients currently on dialysis and the absence of transfusion during posttransplant follow-up suggest that most patients acquired HCV infection through transfusion during dialysis. The proportion of anti-HCV-positive patients who had one or more episodes of elevation in serum transaminase level was similar to that of hepatitis B surface antigen (HBsAg)-positive patients, 75% vs. 72.2%. However, anti-HCV was only detected in 25% of HBsAg-negative patients who had recurrent elevations in serum transaminase level. It is not clear whether the low prevalence of anti-HCV in these patients is related to the presence of other non-A, non-B hepatitis virus (es) or a decrease in titer of anti-HCV secondary to immunosuppression posttransplantation.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.transplantjournal.comen_US
dc.relation.ispartofTransplantationen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAntilymphocyte Serum - Blooden_US
dc.subject.meshBlood Transfusion - Adverse Effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis B Antigens - Analysisen_US
dc.subject.meshHepatitis C - Epidemiology - Etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Transplantation - Adverse Effectsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPeritoneal Dialysis, Continuous Ambulatory - Adverse Effectsen_US
dc.subject.meshRenal Dialysis - Adverse Effectsen_US
dc.titleHepatitis C in renal transplant recipientsen_US
dc.typeArticleen_US
dc.identifier.emailChan, TM:dtmchan@hku.hken_US
dc.identifier.authorityChan, TM=rp00394en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00007890-199111000-00010-
dc.identifier.pmid1949165-
dc.identifier.scopuseid_2-s2.0-0025750105en_US
dc.identifier.volume52en_US
dc.identifier.issue5en_US
dc.identifier.spage810en_US
dc.identifier.epage813en_US
dc.identifier.isiWOS:A1991GQ21300010-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChan, TM=7402687700en_US
dc.identifier.scopusauthoridLok, ASF=35379868500en_US
dc.identifier.scopusauthoridCheng, IKP=7102537483en_US

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