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Article: Discriminant factors affecting early outcome of radioiodine treatment for Graves' disease

TitleDiscriminant factors affecting early outcome of radioiodine treatment for Graves' disease
Authors
Issue Date1990
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/crad
Citation
Clinical Radiology, 1990, v. 42 n. 1, p. 52-54 How to Cite?
AbstractPretreatment clinical, biochemical, iodine-131 (131I) scan and tracer-kinetic parameters were studied in 827 Chinese patients with Graves' disease treated with radioactive iodine. One year after 131I therapy, 56.7% were euthyroid, 33.9% were still thyrotoxic and 9.4% were hypothyroid. Discriminant analysis of all pretreatment variables identified thyroid mass, presenting free thyroxine index and 4 h 131I uptake as the three variables most helpful in discriminating the early outcome group of 131I therapy. The findings suggest that patients with large goitres and severe disease may require higher doses of 131I for treatment of Graves' disease.
Persistent Identifierhttp://hdl.handle.net/10722/161844
ISSN
2015 Impact Factor: 2.151
2015 SCImago Journal Rankings: 0.864
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKung, AWCen_US
dc.contributor.authorChoi, Pen_US
dc.contributor.authorLam, KSLen_US
dc.contributor.authorPun, KKen_US
dc.contributor.authorWang, Cen_US
dc.contributor.authorYeung, RTTen_US
dc.date.accessioned2012-09-05T05:15:27Z-
dc.date.available2012-09-05T05:15:27Z-
dc.date.issued1990en_US
dc.identifier.citationClinical Radiology, 1990, v. 42 n. 1, p. 52-54en_US
dc.identifier.issn0009-9260en_US
dc.identifier.urihttp://hdl.handle.net/10722/161844-
dc.description.abstractPretreatment clinical, biochemical, iodine-131 (131I) scan and tracer-kinetic parameters were studied in 827 Chinese patients with Graves' disease treated with radioactive iodine. One year after 131I therapy, 56.7% were euthyroid, 33.9% were still thyrotoxic and 9.4% were hypothyroid. Discriminant analysis of all pretreatment variables identified thyroid mass, presenting free thyroxine index and 4 h 131I uptake as the three variables most helpful in discriminating the early outcome group of 131I therapy. The findings suggest that patients with large goitres and severe disease may require higher doses of 131I for treatment of Graves' disease.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/craden_US
dc.relation.ispartofClinical Radiologyen_US
dc.subject.meshAdulten_US
dc.subject.meshDose-Response Relationship, Radiationen_US
dc.subject.meshFemaleen_US
dc.subject.meshGraves Disease - Metabolism - Radiotherapyen_US
dc.subject.meshHumansen_US
dc.subject.meshIodine Radioisotopes - Metabolism - Therapeutic Useen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrognosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshThyroid Gland - Metabolismen_US
dc.subject.meshTime Factorsen_US
dc.titleDiscriminant factors affecting early outcome of radioiodine treatment for Graves' diseaseen_US
dc.typeArticleen_US
dc.identifier.emailKung, AWC:awckung@hku.hken_US
dc.identifier.emailLam, KSL:ksllam@hku.hken_US
dc.identifier.authorityKung, AWC=rp00368en_US
dc.identifier.authorityLam, KSL=rp00343en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0009-9260(05)81624-1en_US
dc.identifier.pmid2390837en_US
dc.identifier.scopuseid_2-s2.0-0025351473en_US
dc.identifier.volume42en_US
dc.identifier.issue1en_US
dc.identifier.spage52en_US
dc.identifier.epage54en_US
dc.identifier.isiWOS:A1990DN30800013-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridKung, AWC=7102322339en_US
dc.identifier.scopusauthoridChoi, P=7102909162en_US
dc.identifier.scopusauthoridLam, KSL=8082870600en_US
dc.identifier.scopusauthoridPun, KK=7006538877en_US
dc.identifier.scopusauthoridWang, C=7501631357en_US
dc.identifier.scopusauthoridYeung, RTT=7102833337en_US

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