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Article: Hepatocellular carcinoma in Chinese males and females. Possible causes for the male predominance

TitleHepatocellular carcinoma in Chinese males and females. Possible causes for the male predominance
Authors
Issue Date1987
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741
Citation
Cancer, 1987, v. 60 n. 5, p. 1107-1110 How to Cite?
AbstractThe male-female ratio in 186 hepatocellular carcinoma (HCC) Chinese patients was 5:1. The clinical presentation, biochemical parameters, and histologic findings were the same in both sexes except for a higher proportion of underlying cirrhosis (P = 0.02), and spider naevi (P = 0.04) in the men. There were also more smokers and alcohol drinkers among the men. Over 75% of both sexes were positive for the hepatitis B surface antigen. The possible contributory factors to the predominance of males to females in HCC included: the association with the hepatitis B virus, the higher proportion of male cirrhotics, smoking, and alcohol drinking. The survival probability for both sexes was equally poor; the median survival was 8 weeks for males and 10 weeks for females.
Persistent Identifierhttp://hdl.handle.net/10722/161738
ISSN
2015 Impact Factor: 5.649
2015 SCImago Journal Rankings: 3.188
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLai, CLen_US
dc.contributor.authorGregory, PBen_US
dc.contributor.authorWu, PCen_US
dc.contributor.authorLok, ASFen_US
dc.contributor.authorWong, KPen_US
dc.contributor.authorNg, MMTen_US
dc.date.accessioned2012-09-05T05:14:34Z-
dc.date.available2012-09-05T05:14:34Z-
dc.date.issued1987en_US
dc.identifier.citationCancer, 1987, v. 60 n. 5, p. 1107-1110en_US
dc.identifier.issn0008-543Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/161738-
dc.description.abstractThe male-female ratio in 186 hepatocellular carcinoma (HCC) Chinese patients was 5:1. The clinical presentation, biochemical parameters, and histologic findings were the same in both sexes except for a higher proportion of underlying cirrhosis (P = 0.02), and spider naevi (P = 0.04) in the men. There were also more smokers and alcohol drinkers among the men. Over 75% of both sexes were positive for the hepatitis B surface antigen. The possible contributory factors to the predominance of males to females in HCC included: the association with the hepatitis B virus, the higher proportion of male cirrhotics, smoking, and alcohol drinking. The survival probability for both sexes was equally poor; the median survival was 8 weeks for males and 10 weeks for females.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741en_US
dc.relation.ispartofCanceren_US
dc.subject.meshActuarial Analysisen_US
dc.subject.meshAlcohol Drinkingen_US
dc.subject.meshCarcinoma, Hepatocellular - Epidemiology - Mortality - Pathologyen_US
dc.subject.meshChina - Ethnologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis B Surface Antigens - Analysisen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Cirrhosis - Pathologyen_US
dc.subject.meshLiver Neoplasms - Epidemiology - Mortality - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSex Factorsen_US
dc.subject.meshSmokingen_US
dc.titleHepatocellular carcinoma in Chinese males and females. Possible causes for the male predominanceen_US
dc.typeArticleen_US
dc.identifier.emailLai, CL:hrmelcl@hku.hken_US
dc.identifier.authorityLai, CL=rp00314en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/1097-0142(19870901)60:5<1107::AID-CNCR2820600531>3.0.CO;2-O-
dc.identifier.pmid3038298-
dc.identifier.scopuseid_2-s2.0-0023619777en_US
dc.identifier.volume60en_US
dc.identifier.issue5en_US
dc.identifier.spage1107en_US
dc.identifier.epage1110en_US
dc.identifier.isiWOS:A1987J662600030-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLai, CL=7403086396en_US
dc.identifier.scopusauthoridGregory, PB=7201745266en_US
dc.identifier.scopusauthoridWu, PC=7403119323en_US
dc.identifier.scopusauthoridLok, ASF=35379868500en_US
dc.identifier.scopusauthoridWong, KP=37125734900en_US
dc.identifier.scopusauthoridNg, MMT=7202076310en_US

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