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Article: Quantitative morphology of mitochondria in hepatocellular carcinoma and chronic liver disease

TitleQuantitative morphology of mitochondria in hepatocellular carcinoma and chronic liver disease
Authors
Issue Date1984
Citation
Archives Of Pathology And Laboratory Medicine, 1984, v. 108 n. 11, p. 914-916 How to Cite?
AbstractA morphometric method was applied to measure the size, number, and surface membranes of the mitochondria in cells obtained from hepatitis B-associated hepatocellular carcinoma (HCC), from cirrhotic portions of livers with and without HCC, and from alcoholic liver disease (ALD). The mitochondria in HCC cells showed a significantly higher numerical density and surface density of internal membranes and cristae than mitochondria in cirrhosis and ALD. The findings suggest an increased functional activity of mitochondria in HCC.
Persistent Identifierhttp://hdl.handle.net/10722/161681
ISSN
2015 Impact Factor: 2.631
2015 SCImago Journal Rankings: 1.158
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWu, PCen_US
dc.contributor.authorLai, CLen_US
dc.contributor.authorLiddel, RHAen_US
dc.date.accessioned2012-09-05T05:13:51Z-
dc.date.available2012-09-05T05:13:51Z-
dc.date.issued1984en_US
dc.identifier.citationArchives Of Pathology And Laboratory Medicine, 1984, v. 108 n. 11, p. 914-916en_US
dc.identifier.issn0003-9985en_US
dc.identifier.urihttp://hdl.handle.net/10722/161681-
dc.description.abstractA morphometric method was applied to measure the size, number, and surface membranes of the mitochondria in cells obtained from hepatitis B-associated hepatocellular carcinoma (HCC), from cirrhotic portions of livers with and without HCC, and from alcoholic liver disease (ALD). The mitochondria in HCC cells showed a significantly higher numerical density and surface density of internal membranes and cristae than mitochondria in cirrhosis and ALD. The findings suggest an increased functional activity of mitochondria in HCC.en_US
dc.languageengen_US
dc.relation.ispartofArchives of Pathology and Laboratory Medicineen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCarcinoma, Hepatocellular - Pathologyen_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Cirrhosis - Pathologyen_US
dc.subject.meshLiver Diseases, Alcoholic - Pathologyen_US
dc.subject.meshLiver Neoplasms - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMitochondria, Liver - Pathology - Ultrastructureen_US
dc.titleQuantitative morphology of mitochondria in hepatocellular carcinoma and chronic liver diseaseen_US
dc.typeArticleen_US
dc.identifier.emailLai, CL:hrmelcl@hku.hken_US
dc.identifier.authorityLai, CL=rp00314en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid6091592-
dc.identifier.scopuseid_2-s2.0-0021680653en_US
dc.identifier.volume108en_US
dc.identifier.issue11en_US
dc.identifier.spage914en_US
dc.identifier.epage916en_US
dc.identifier.isiWOS:A1984TP60000025-
dc.identifier.scopusauthoridWu, PC=7403119323en_US
dc.identifier.scopusauthoridLai, CL=7403086396en_US
dc.identifier.scopusauthoridLiddel, RHA=6504540490en_US

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