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Article: Clinical features of hepatocellular carcinoma: Review of 211 patients in Hong Kong

TitleClinical features of hepatocellular carcinoma: Review of 211 patients in Hong Kong
Authors
Issue Date1981
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741
Citation
Cancer, 1981, v. 47 n. 11, p. 2746-2755 How to Cite?
AbstractA retrospective study of 211 patients with proven hepatocellular carcinoma (HCC) was made. The commonest symptoms were anorexia and malaise (73%). Five patients (2.5%) had near-normal biochemical tests despite the presence of massive tumors. Diagnostic yield from angiography, percutaneous peritoneoscopic biopsy, or scintiscanning was 87-98%. Three percent of the patients had resectable tumors. Median survival for patients with untreated disease was 3.5 weeks. Apart from histology, the total serum bilirubin level was the only factor of prognostic value. Only 12 patients had preexisting symptomatic cirrhosis. When compared with 80 patients with symptomatic postnecrotic cirrhosis without malignancy, patients with HCC had higher SGOT:SGPT ratio, higher serum albumin levels, and higher platelet counts. There was only minimal overlap of patients with symptomatic postnecrotic cirrhosis and those with HCC. The authors conclude that their patients with HCC appeared late for treatment. A probable difference in the development of symptomatic postnecrotic cirrhosis and of HCC with asymptomatic postnecrotic cirrhosis is suggested.
Persistent Identifierhttp://hdl.handle.net/10722/161660
ISSN
2023 Impact Factor: 6.1
2023 SCImago Journal Rankings: 2.887
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLai, CLen_US
dc.contributor.authorLam, KCen_US
dc.contributor.authorWong, KPen_US
dc.date.accessioned2012-09-05T05:13:39Z-
dc.date.available2012-09-05T05:13:39Z-
dc.date.issued1981en_US
dc.identifier.citationCancer, 1981, v. 47 n. 11, p. 2746-2755en_US
dc.identifier.issn0008-543Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/161660-
dc.description.abstractA retrospective study of 211 patients with proven hepatocellular carcinoma (HCC) was made. The commonest symptoms were anorexia and malaise (73%). Five patients (2.5%) had near-normal biochemical tests despite the presence of massive tumors. Diagnostic yield from angiography, percutaneous peritoneoscopic biopsy, or scintiscanning was 87-98%. Three percent of the patients had resectable tumors. Median survival for patients with untreated disease was 3.5 weeks. Apart from histology, the total serum bilirubin level was the only factor of prognostic value. Only 12 patients had preexisting symptomatic cirrhosis. When compared with 80 patients with symptomatic postnecrotic cirrhosis without malignancy, patients with HCC had higher SGOT:SGPT ratio, higher serum albumin levels, and higher platelet counts. There was only minimal overlap of patients with symptomatic postnecrotic cirrhosis and those with HCC. The authors conclude that their patients with HCC appeared late for treatment. A probable difference in the development of symptomatic postnecrotic cirrhosis and of HCC with asymptomatic postnecrotic cirrhosis is suggested.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741en_US
dc.relation.ispartofCanceren_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAlanine Transaminase - Blooden_US
dc.subject.meshAnorexia - Diagnosisen_US
dc.subject.meshAspartate Aminotransferases - Blooden_US
dc.subject.meshBilirubin - Blooden_US
dc.subject.meshCarcinoma, Hepatocellular - Diagnosis - Mortalityen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Cirrhosis - Diagnosisen_US
dc.subject.meshLiver Neoplasms - Diagnosis - Mortalityen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPlatelet Counten_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSerum Albumin - Analysisen_US
dc.titleClinical features of hepatocellular carcinoma: Review of 211 patients in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailLai, CL:hrmelcl@hku.hken_US
dc.identifier.authorityLai, CL=rp00314en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/1097-0142(19810601)47:11<2746::AID-CNCR2820471134>3.0.CO;2-K-
dc.identifier.pmid6266641-
dc.identifier.scopuseid_2-s2.0-0019475636en_US
dc.identifier.volume47en_US
dc.identifier.issue11en_US
dc.identifier.spage2746en_US
dc.identifier.epage2755en_US
dc.identifier.isiWOS:A1981LS34100031-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLai, CL=7403086396en_US
dc.identifier.scopusauthoridLam, KC=7403657286en_US
dc.identifier.scopusauthoridWong, KP=37125734900en_US
dc.identifier.issnl0008-543X-

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