File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Etiological spectrum of liver cirrhosis in the Chinese

TitleEtiological spectrum of liver cirrhosis in the Chinese
Authors
Issue Date1980
Citation
Journal Of Chronic Diseases, 1980, v. 33 n. 6, p. 375-381 How to Cite?
AbstractA combined prospective-retrospective hospital study for the etiological spectrum of non-hepatomatous liver cirrhosis in the Chinese in Hong Kong was performed on a total of 731 patients. In the prospective part, the three commonest causes of liver cirrhosis in the population were found to be chronic active type-B hepatitis, alcoholic liver disease and cryptogenic cirrhosis. In the retrospective analysis, before tests for HBsAg were available, the commonest cause was cryptogenic cirrhosis. Of 60 patients who had previously been so diagnosed and were re-studied prospectively later, 50 were found to have chronic active type-B hepatitis. The frequency of this disease showed no sign of falling between the years 1962 and 1976. Alcoholic liver disease was increasingly more common (χn2 = 14.3, p , 0.001). The rising frequency of alcoholic cirrhosis between 1962 and 1976 approximated the average per capita expenditure on alcoholic drink in the community during the same period. Although there was an increasing tendency to take Western liquors, consumers of Chinese wines currently still accounted for 75% of those who had steady alcoholic intake. Haemochromatosis was the cause of cirrhosis in only one out of the 731 patients. We concluded: (1) that hepatitis B virus infection was the most important cause of liver cirrhosis in the Chinese in Hong Kong, and this importance was undiminished over the last 15 yr, (2) that alcoholism was an increasingly important cause of liver cirrhosis in our increasingly affluent and 'Westernised' society, and (3) that the majority of patients previously labelled as having 'cryptogenic' postnecrotic cirrhosis were suffering from hepatitis B virus infection and, therefore, former metabolic data on liver cirrhosis published from this Department dominantly applied to HBsAg-positive cirrhosis.
Persistent Identifierhttp://hdl.handle.net/10722/161651
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, KCen_US
dc.contributor.authorLai, CLen_US
dc.contributor.authorWu, PCen_US
dc.contributor.authorDodd, Den_US
dc.date.accessioned2012-09-05T05:13:32Z-
dc.date.available2012-09-05T05:13:32Z-
dc.date.issued1980en_US
dc.identifier.citationJournal Of Chronic Diseases, 1980, v. 33 n. 6, p. 375-381en_US
dc.identifier.issn0021-9681en_US
dc.identifier.urihttp://hdl.handle.net/10722/161651-
dc.description.abstractA combined prospective-retrospective hospital study for the etiological spectrum of non-hepatomatous liver cirrhosis in the Chinese in Hong Kong was performed on a total of 731 patients. In the prospective part, the three commonest causes of liver cirrhosis in the population were found to be chronic active type-B hepatitis, alcoholic liver disease and cryptogenic cirrhosis. In the retrospective analysis, before tests for HBsAg were available, the commonest cause was cryptogenic cirrhosis. Of 60 patients who had previously been so diagnosed and were re-studied prospectively later, 50 were found to have chronic active type-B hepatitis. The frequency of this disease showed no sign of falling between the years 1962 and 1976. Alcoholic liver disease was increasingly more common (χn2 = 14.3, p , 0.001). The rising frequency of alcoholic cirrhosis between 1962 and 1976 approximated the average per capita expenditure on alcoholic drink in the community during the same period. Although there was an increasing tendency to take Western liquors, consumers of Chinese wines currently still accounted for 75% of those who had steady alcoholic intake. Haemochromatosis was the cause of cirrhosis in only one out of the 731 patients. We concluded: (1) that hepatitis B virus infection was the most important cause of liver cirrhosis in the Chinese in Hong Kong, and this importance was undiminished over the last 15 yr, (2) that alcoholism was an increasingly important cause of liver cirrhosis in our increasingly affluent and 'Westernised' society, and (3) that the majority of patients previously labelled as having 'cryptogenic' postnecrotic cirrhosis were suffering from hepatitis B virus infection and, therefore, former metabolic data on liver cirrhosis published from this Department dominantly applied to HBsAg-positive cirrhosis.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Chronic Diseasesen_US
dc.subject.meshChina - Ethnologyen_US
dc.subject.meshHepatitis B - Complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshJapanen_US
dc.subject.meshLiver Cirrhosis - Diagnosis - Epidemiology - Etiologyen_US
dc.subject.meshLiver Cirrhosis, Alcoholic - Epidemiology - Etiologyen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRetrospective Studiesen_US
dc.titleEtiological spectrum of liver cirrhosis in the Chineseen_US
dc.typeArticleen_US
dc.identifier.emailLai, CL:hrmelcl@hku.hken_US
dc.identifier.authorityLai, CL=rp00314en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0021-9681(80)90047-8-
dc.identifier.pmid7372773-
dc.identifier.scopuseid_2-s2.0-0018850765en_US
dc.identifier.volume33en_US
dc.identifier.issue6en_US
dc.identifier.spage375en_US
dc.identifier.epage381en_US
dc.identifier.isiWOS:A1980JS57600006-
dc.identifier.scopusauthoridLam, KC=7403657286en_US
dc.identifier.scopusauthoridLai, CL=7403086396en_US
dc.identifier.scopusauthoridWu, PC=7403119323en_US
dc.identifier.scopusauthoridDodd, D=35849863300en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats