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Conference Paper: The effect of macrophages on putative stem/progenitor cells in endometriosis
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TitleThe effect of macrophages on putative stem/progenitor cells in endometriosis
 
AuthorsChan, RWS
Chan, YY
Lee, CL
Ng, EHY
Yeung, WSB
 
KeywordsMedical sciences
Obstetrics and gynecology medical sciences
Endocrinology pharmacy and pharmacology
 
Issue Date2012
 
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
 
CitationThe 28th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey, 1-4 July 2012. In Human Reproduction, 2012, v. 27 suppl. 2, p. ii118-ii120, abstract O-303 [How to Cite?]
DOI: http://dx.doi.org/10.1093/humrep/27.s2.72
 
AbstractINTRODUCTION: Women with endometriosis have altered immunologic responses and defective immunosurveillance can lead to persistence and growth of menstrual debris at ectopic sites. Macrophages are key players of the natural immunity and are more activated in patients with endometriosis1. Stem cells have been found in human endometrium2 and ovarian endometrioma3 and they exhibit clonogenic activity3, 4 (ability to form large colony forming units, CFUs). Since the pathogenesis of endometriosis remains uncertain, we hypothesis that women with endometriosis are more likely to shed endometrial stem/progenitor cells during menses and these cells can rapidly grow at ectopic tissue upon exposure to a conducive environment. In this study, we examined: 1) the cloning efficiency of endometriotic cells when co-cultured with macrophages, 2) the invasiveness of endometriotic progenies after macrophage exposure, and 3) the cytokine profile of macrophages from women with/without endo…
 
DescriptionThis journal suppl. entitled: Abstract book of the 28th ESHRE Annual Meeting ... 2012
Oral Presentation - Session 74: Endometriosis/Endometrium: Molecular and Cellular Insights 3: abstracts O-303
 
ISSN0268-1161
2013 Impact Factor: 4.585
 
DOIhttp://dx.doi.org/10.1093/humrep/27.s2.72
 
DC FieldValue
dc.contributor.authorChan, RWS
 
dc.contributor.authorChan, YY
 
dc.contributor.authorLee, CL
 
dc.contributor.authorNg, EHY
 
dc.contributor.authorYeung, WSB
 
dc.date.accessioned2012-08-16T06:15:33Z
 
dc.date.available2012-08-16T06:15:33Z
 
dc.date.issued2012
 
dc.description.abstractINTRODUCTION: Women with endometriosis have altered immunologic responses and defective immunosurveillance can lead to persistence and growth of menstrual debris at ectopic sites. Macrophages are key players of the natural immunity and are more activated in patients with endometriosis1. Stem cells have been found in human endometrium2 and ovarian endometrioma3 and they exhibit clonogenic activity3, 4 (ability to form large colony forming units, CFUs). Since the pathogenesis of endometriosis remains uncertain, we hypothesis that women with endometriosis are more likely to shed endometrial stem/progenitor cells during menses and these cells can rapidly grow at ectopic tissue upon exposure to a conducive environment. In this study, we examined: 1) the cloning efficiency of endometriotic cells when co-cultured with macrophages, 2) the invasiveness of endometriotic progenies after macrophage exposure, and 3) the cytokine profile of macrophages from women with/without endo…
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionThis journal suppl. entitled: Abstract book of the 28th ESHRE Annual Meeting ... 2012
 
dc.descriptionOral Presentation - Session 74: Endometriosis/Endometrium: Molecular and Cellular Insights 3: abstracts O-303
 
dc.identifier.citationThe 28th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey, 1-4 July 2012. In Human Reproduction, 2012, v. 27 suppl. 2, p. ii118-ii120, abstract O-303 [How to Cite?]
DOI: http://dx.doi.org/10.1093/humrep/27.s2.72
 
dc.identifier.doihttp://dx.doi.org/10.1093/humrep/27.s2.72
 
dc.identifier.epageii120
 
dc.identifier.hkuros202787
 
dc.identifier.issn0268-1161
2013 Impact Factor: 4.585
 
dc.identifier.issuesuppl. 2
 
dc.identifier.spageii118
 
dc.identifier.urihttp://hdl.handle.net/10722/160628
 
dc.identifier.volume27
 
dc.languageeng
 
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofHuman Reproduction
 
dc.subjectMedical sciences
 
dc.subjectObstetrics and gynecology medical sciences
 
dc.subjectEndocrinology pharmacy and pharmacology
 
dc.titleThe effect of macrophages on putative stem/progenitor cells in endometriosis
 
dc.typeConference_Paper
 
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<contributor.author>Lee, CL</contributor.author>
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<contributor.author>Yeung, WSB</contributor.author>
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