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Conference Paper: The effect of macrophages on putative stem/progenitor cells in endometriosis

TitleThe effect of macrophages on putative stem/progenitor cells in endometriosis
Authors
KeywordsMedical sciences
Obstetrics and gynecology medical sciences
Endocrinology pharmacy and pharmacology
Issue Date2012
PublisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/
Citation
The 28th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey, 1-4 July 2012. In Human Reproduction, 2012, v. 27 suppl. 2, p. ii118-ii120, abstract O-303 How to Cite?
AbstractINTRODUCTION: Women with endometriosis have altered immunologic responses and defective immunosurveillance can lead to persistence and growth of menstrual debris at ectopic sites. Macrophages are key players of the natural immunity and are more activated in patients with endometriosis1. Stem cells have been found in human endometrium2 and ovarian endometrioma3 and they exhibit clonogenic activity3, 4 (ability to form large colony forming units, CFUs). Since the pathogenesis of endometriosis remains uncertain, we hypothesis that women with endometriosis are more likely to shed endometrial stem/progenitor cells during menses and these cells can rapidly grow at ectopic tissue upon exposure to a conducive environment. In this study, we examined: 1) the cloning efficiency of endometriotic cells when co-cultured with macrophages, 2) the invasiveness of endometriotic progenies after macrophage exposure, and 3) the cytokine profile of macrophages from women with/without endo…
DescriptionThis journal suppl. entitled: Abstract book of the 28th ESHRE Annual Meeting ... 2012
Oral Presentation - Session 74: Endometriosis/Endometrium: Molecular and Cellular Insights 3: abstracts O-303
Persistent Identifierhttp://hdl.handle.net/10722/160628
ISSN
2014 Impact Factor: 4.569

 

DC FieldValueLanguage
dc.contributor.authorChan, RWSen_US
dc.contributor.authorChan, YYen_US
dc.contributor.authorLee, CLen_US
dc.contributor.authorNg, EHYen_US
dc.contributor.authorYeung, WSBen_US
dc.date.accessioned2012-08-16T06:15:33Z-
dc.date.available2012-08-16T06:15:33Z-
dc.date.issued2012en_US
dc.identifier.citationThe 28th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey, 1-4 July 2012. In Human Reproduction, 2012, v. 27 suppl. 2, p. ii118-ii120, abstract O-303en_US
dc.identifier.issn0268-1161-
dc.identifier.urihttp://hdl.handle.net/10722/160628-
dc.descriptionThis journal suppl. entitled: Abstract book of the 28th ESHRE Annual Meeting ... 2012-
dc.descriptionOral Presentation - Session 74: Endometriosis/Endometrium: Molecular and Cellular Insights 3: abstracts O-303-
dc.description.abstractINTRODUCTION: Women with endometriosis have altered immunologic responses and defective immunosurveillance can lead to persistence and growth of menstrual debris at ectopic sites. Macrophages are key players of the natural immunity and are more activated in patients with endometriosis1. Stem cells have been found in human endometrium2 and ovarian endometrioma3 and they exhibit clonogenic activity3, 4 (ability to form large colony forming units, CFUs). Since the pathogenesis of endometriosis remains uncertain, we hypothesis that women with endometriosis are more likely to shed endometrial stem/progenitor cells during menses and these cells can rapidly grow at ectopic tissue upon exposure to a conducive environment. In this study, we examined: 1) the cloning efficiency of endometriotic cells when co-cultured with macrophages, 2) the invasiveness of endometriotic progenies after macrophage exposure, and 3) the cytokine profile of macrophages from women with/without endo…-
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://humrep.oxfordjournals.org/-
dc.relation.ispartofHuman Reproductionen_US
dc.subjectMedical sciences-
dc.subjectObstetrics and gynecology medical sciences-
dc.subjectEndocrinology pharmacy and pharmacology-
dc.titleThe effect of macrophages on putative stem/progenitor cells in endometriosisen_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, RWS: rwschan@hku.hken_US
dc.identifier.emailLee, CL: kcllee@hku.hken_US
dc.identifier.emailNg, EHY: nghye@hku.hken_US
dc.identifier.emailYeung, WSB: wsbyeung@hkucc.hku.hken_US
dc.identifier.authorityNg, EHY=rp00426en_US
dc.identifier.authorityYeung, WSB=rp00331en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/humrep/27.s2.72-
dc.identifier.hkuros202787en_US
dc.identifier.volume27-
dc.identifier.issuesuppl. 2-
dc.identifier.spageii118-
dc.identifier.epageii120-
dc.publisher.placeUnited Kingdom-
dc.customcontrol.immutablesml 131202-

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