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Conference Paper: Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 mediated notch signaling in human ovarian cancer cells
Title | Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 mediated notch signaling in human ovarian cancer cells |
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Authors | |
Keywords | Medical sciences Oncology |
Issue Date | 2012 |
Publisher | Pergamon. The Journal's web site is located at http://www.elsevier.com/locate/ejca |
Citation | The 22nd Annual Congress of the European Association of Cancer Research (EACR-22), Barcelona, Spain, 7-10 July 2012. In European Journal of Cancer, 2012, v. 48 suppl. 5, p. S129, abstract no. 545 How to Cite? |
Abstract | BACKGROUND: Ovarian cancer is one of the most deadly gynaecological malignancies worldwide. Adjuvant chemotherapy combined with other treatments is the current management of the advanced ovarian cancers. However, the acquisition of resistance to initially responsive tumors limits the successful curative rate. The underlying molecular mechanism remains largely unknown. Here, we report that the downregulation of miR-199b-5p leading to elevated JAG1-mediated NOTCH signal... |
Description | This journal suppl. entitled: 22nd Biennial Congress of the European Association for Cancer Research - proceedings of EACR 22 |
Persistent Identifier | http://hdl.handle.net/10722/153220 |
ISSN | 2023 Impact Factor: 7.6 2023 SCImago Journal Rankings: 2.501 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Liu, X | en_US |
dc.contributor.author | Chan, W | en_US |
dc.contributor.author | Ngan, YS | en_US |
dc.date.accessioned | 2012-07-16T10:00:23Z | - |
dc.date.available | 2012-07-16T10:00:23Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | The 22nd Annual Congress of the European Association of Cancer Research (EACR-22), Barcelona, Spain, 7-10 July 2012. In European Journal of Cancer, 2012, v. 48 suppl. 5, p. S129, abstract no. 545 | en_US |
dc.identifier.issn | 0959-8049 | - |
dc.identifier.uri | http://hdl.handle.net/10722/153220 | - |
dc.description | This journal suppl. entitled: 22nd Biennial Congress of the European Association for Cancer Research - proceedings of EACR 22 | - |
dc.description.abstract | BACKGROUND: Ovarian cancer is one of the most deadly gynaecological malignancies worldwide. Adjuvant chemotherapy combined with other treatments is the current management of the advanced ovarian cancers. However, the acquisition of resistance to initially responsive tumors limits the successful curative rate. The underlying molecular mechanism remains largely unknown. Here, we report that the downregulation of miR-199b-5p leading to elevated JAG1-mediated NOTCH signal... | - |
dc.language | eng | en_US |
dc.publisher | Pergamon. The Journal's web site is located at http://www.elsevier.com/locate/ejca | - |
dc.relation.ispartof | European Journal of Cancer | en_US |
dc.rights | NOTICE: this is the author’s version of a work that was accepted for publication in European Journal of Cancer. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in European Journal of Cancer, v. 48 suppl. 5, July 2012, doi: 10.1016/S0959-8049(12)71204-2 | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Medical sciences | - |
dc.subject | Oncology | - |
dc.title | Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 mediated notch signaling in human ovarian cancer cells | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Chan, W: dwchan@hku.hk | en_US |
dc.identifier.email | Ngan, YS: hysngan@hkucc.hku.hk | en_US |
dc.identifier.authority | Chan, W=rp00543 | en_US |
dc.identifier.authority | Ngan, YS=rp00346 | en_US |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1016/S0959-8049(12)71204-2 | - |
dc.identifier.hkuros | 201592 | en_US |
dc.identifier.volume | 48 | - |
dc.identifier.issue | suppl. 5 | - |
dc.identifier.spage | S129, abstract no. 545 | - |
dc.identifier.epage | S129, abstract no. 545 | - |
dc.identifier.isi | WOS:000313036501048 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0959-8049 | - |