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Conference Paper: Downregulation of miR-199b-5p is associated with chemoresistance via Jagged1 mediated notch signaling in human ovarian cancer cells
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TitleDownregulation of miR-199b-5p is associated with chemoresistance via Jagged1 mediated notch signaling in human ovarian cancer cells
 
AuthorsLiu, X
Chan, W
Ngan, YS
 
KeywordsMedical sciences
Oncology
 
Issue Date2012
 
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/ejca
 
CitationThe 22nd Annual Congress of the European Association of Cancer Research (EACR), Barcelona, Spain, 7-10 July 2012. In European Journal of Cancer, 2012, v. 48 suppl. 5, p. S129, abstract no. 545 [How to Cite?]
DOI: http://dx.doi.org/10.1016/S0959-8049(12)71204-2
 
AbstractBACKGROUND: Ovarian cancer is one of the most deadly gynaecological malignancies worldwide. Adjuvant chemotherapy combined with other treatments is the current management of the advanced ovarian cancers. However, the acquisition of resistance to initially responsive tumors limits the successful curative rate. The underlying molecular mechanism remains largely unknown. Here, we report that the downregulation of miR-199b-5p leading to elevated JAG1-mediated NOTCH signal...
 
DescriptionThis journal suppl. entitled: 22nd Biennial Congress of the European Association for Cancer Research - proceedings of EACR 22
 
ISSN0959-8049
2012 Impact Factor: 5.061
2012 SCImago Journal Rankings: 2.346
 
DOIhttp://dx.doi.org/10.1016/S0959-8049(12)71204-2
 
DC FieldValue
dc.contributor.authorLiu, X
 
dc.contributor.authorChan, W
 
dc.contributor.authorNgan, YS
 
dc.date.accessioned2012-07-16T10:00:23Z
 
dc.date.available2012-07-16T10:00:23Z
 
dc.date.issued2012
 
dc.description.abstractBACKGROUND: Ovarian cancer is one of the most deadly gynaecological malignancies worldwide. Adjuvant chemotherapy combined with other treatments is the current management of the advanced ovarian cancers. However, the acquisition of resistance to initially responsive tumors limits the successful curative rate. The underlying molecular mechanism remains largely unknown. Here, we report that the downregulation of miR-199b-5p leading to elevated JAG1-mediated NOTCH signal...
 
dc.description.naturepostprint
 
dc.descriptionThis journal suppl. entitled: 22nd Biennial Congress of the European Association for Cancer Research - proceedings of EACR 22
 
dc.identifier.citationThe 22nd Annual Congress of the European Association of Cancer Research (EACR), Barcelona, Spain, 7-10 July 2012. In European Journal of Cancer, 2012, v. 48 suppl. 5, p. S129, abstract no. 545 [How to Cite?]
DOI: http://dx.doi.org/10.1016/S0959-8049(12)71204-2
 
dc.identifier.doihttp://dx.doi.org/10.1016/S0959-8049(12)71204-2
 
dc.identifier.epageS129
 
dc.identifier.hkuros201592
 
dc.identifier.issn0959-8049
2012 Impact Factor: 5.061
2012 SCImago Journal Rankings: 2.346
 
dc.identifier.issuesuppl. 5
 
dc.identifier.spageS129
 
dc.identifier.urihttp://hdl.handle.net/10722/153220
 
dc.identifier.volume48
 
dc.languageeng
 
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/ejca
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofEuropean Journal of Cancer
 
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in European Journal of Cancer. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in European Journal of Cancer, v. 48 suppl. 5, July 2012, doi: 10.1016/S0959-8049(12)71204-2
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.subjectMedical sciences
 
dc.subjectOncology
 
dc.titleDownregulation of miR-199b-5p is associated with chemoresistance via Jagged1 mediated notch signaling in human ovarian cancer cells
 
dc.typeConference_Paper
 
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