Article: The use of sex hormones in women with rheumatological diseases

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TitleThe use of sex hormones in women with rheumatological diseases
AuthorsLi, RHW1
Gebbie, AE2
Wong, RWS3
Ng, EHY1
Glasier, AF2
Ho, PC1
KeywordsArthritis
Contraceptives
Hormonal
Hormone replacement therapy
Lupus erythematosus
Oral
Rheumatic diseases
Rheumatoid
Systemic
Issue Date2011
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
CitationHong Kong Medical Journal, 2011, v. 17 n. 6, p. 487-491 [How to Cite?]
AbstractA number of rheumatological diseases predominantly affect women of reproductive age. There has always been concern that the use of oestrogen-containing agents such as combined hormonal contraception and hormone therapy might aggravate these conditions. This article reviews the up-to-date evidence regarding the safety of using these agents in women with various rheumatological diseases, with emphasis on systemic lupus erythematosus and rheumatoid arthritis. In the absence of antiphospholipid antibody or other prothrombotic risk factors, combined hormonal contraception is not contra-indicated in most rheumatological conditions including inactive systemic lupus erythematosus. Moreover, hormone therapy is generally not contra-indicated except for women with active systemic lupus erythematosus disease where its effect on disease flare is less clear and individual judgement is required.
DescriptionAuthor Chinese name: Raymond HW Li 李幸奐, Ailsa E Gebbie, Raymond WS Wong 黃煥星, Ernest HY Ng 吳鴻裕, Anna F Glasier, PC Ho 何柏松
ISSN1024-2708
2011 SCImago Journal Rankings: 0.054
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorLi, RHW
dc.contributor.authorGebbie, AE
dc.contributor.authorWong, RWS
dc.contributor.authorNg, EHY
dc.contributor.authorGlasier, AF
dc.contributor.authorHo, PC
dc.date.accessioned2012-07-16T09:52:55Z
dc.date.available2012-07-16T09:52:55Z
dc.date.issued2011
dc.description.abstractA number of rheumatological diseases predominantly affect women of reproductive age. There has always been concern that the use of oestrogen-containing agents such as combined hormonal contraception and hormone therapy might aggravate these conditions. This article reviews the up-to-date evidence regarding the safety of using these agents in women with various rheumatological diseases, with emphasis on systemic lupus erythematosus and rheumatoid arthritis. In the absence of antiphospholipid antibody or other prothrombotic risk factors, combined hormonal contraception is not contra-indicated in most rheumatological conditions including inactive systemic lupus erythematosus. Moreover, hormone therapy is generally not contra-indicated except for women with active systemic lupus erythematosus disease where its effect on disease flare is less clear and individual judgement is required.
dc.description.naturepublished_or_final_version
dc.descriptionAuthor Chinese name: Raymond HW Li 李幸奐, Ailsa E Gebbie, Raymond WS Wong 黃煥星, Ernest HY Ng 吳鴻裕, Anna F Glasier, PC Ho 何柏松
dc.identifier.citationHong Kong Medical Journal, 2011, v. 17 n. 6, p. 487-491 [How to Cite?]
dc.identifier.epage491
dc.identifier.hkuros201400
dc.identifier.issn1024-2708
2011 SCImago Journal Rankings: 0.054
dc.identifier.issue6
dc.identifier.pmid22147320
dc.identifier.scopuseid_2-s2.0-83255176267
dc.identifier.spage487
dc.identifier.urihttp://hdl.handle.net/10722/152944
dc.identifier.volume17
dc.languageeng
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
dc.publisher.placeHong Kong
dc.relation.ispartofHong Kong Medical Journal
dc.relation.referencesReferences in Scopus
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
dc.subject.meshArthritis, Rheumatoid
dc.subject.meshContraceptives, Oral, Combined
dc.subject.meshContraceptives, Oral, Hormonal
dc.subject.meshHormone Replacement Therapy
dc.subject.meshLupus Erythematosus, Systemic
dc.subjectArthritis
dc.subjectContraceptives
dc.subjectHormonal
dc.subjectHormone replacement therapy
dc.subjectLupus erythematosus
dc.subjectOral
dc.subjectRheumatic diseases
dc.subjectRheumatoid
dc.subjectSystemic
dc.titleThe use of sex hormones in women with rheumatological diseases
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Family Planning and Well Women Services
  3. Division of Rheumatology