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Article: Pediatric 64-MDCT coronary angiography with ECG-modulated tube current: Radiation dose and cancer risk

TitlePediatric 64-MDCT coronary angiography with ECG-modulated tube current: Radiation dose and cancer risk
Authors
Issue Date2009
PublisherAmerican Roentgen Ray Society. The Journal's web site is located at http://www.arrs.org/scriptcontent/ajr/index.cfm
Citation
American Journal Of Roentgenology, 2009, v. 193 n. 2, p. 539-544 How to Cite?
AbstractOBJECTIVE. The purpose of our study was to measure the radiation dose from ECG-gated CT coronary angiography in children and to estimate the cancer risk associated with the radiation dose. MATERIALS AND METHODS. Organ doses were measured with a 5-year-old pediatric phantom and thermoluminescent dosimeters on a 64-MDCT scanner. Four retrospectively ECG-gated CT coronary angiography protocols with four simulated heart rates and the corresponding pitches were studied. The lifetime attributable risk of cancer incidence was estimated for children in the United States and Hong Kong according to the National Academies Biologic Effects of Ionizing Radiation VII report. RESULTS. The effective doses were 16.45, 12.17, 11.97, and 11.81 mSv for the four protocols, respectively. The corresponding lifetime attributable risks estimated for 5-year-old U.S. boys and girls were 0.14%-0.20% and 0.43%-0.60%, respectively, and for 5-year-old Hong Kong boys and girls were 0.22%-0.33% and 0.61%-0.85%. In relation to the total cancer incidence (baseline cancer incidence plus lifetime attributable risk), lifetime attributable risk from radiation exposure contributed up to 0.99% and 3.51% for Hong Kong boys and girls and up to 0.46% and 1.57% for U.S. boys and girls. CONCLUSION. Our results suggest that radiation dose and cancer risk of CT coronary angiography to pediatric patients are not negligible, more so in Hong Kong children than in U.S. children. Therefore, these examinations should be well justified clinically. © American Roentgen Ray Society.
Persistent Identifierhttp://hdl.handle.net/10722/150912
ISSN
2015 Impact Factor: 2.66
2015 SCImago Journal Rankings: 1.439
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHuang, Ben_US
dc.contributor.authorLaw, MWMen_US
dc.contributor.authorMak, HKFen_US
dc.contributor.authorKwok, SPFen_US
dc.contributor.authorKhong, PLen_US
dc.date.accessioned2012-06-26T06:14:21Z-
dc.date.available2012-06-26T06:14:21Z-
dc.date.issued2009en_US
dc.identifier.citationAmerican Journal Of Roentgenology, 2009, v. 193 n. 2, p. 539-544en_US
dc.identifier.issn0361-803Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/150912-
dc.description.abstractOBJECTIVE. The purpose of our study was to measure the radiation dose from ECG-gated CT coronary angiography in children and to estimate the cancer risk associated with the radiation dose. MATERIALS AND METHODS. Organ doses were measured with a 5-year-old pediatric phantom and thermoluminescent dosimeters on a 64-MDCT scanner. Four retrospectively ECG-gated CT coronary angiography protocols with four simulated heart rates and the corresponding pitches were studied. The lifetime attributable risk of cancer incidence was estimated for children in the United States and Hong Kong according to the National Academies Biologic Effects of Ionizing Radiation VII report. RESULTS. The effective doses were 16.45, 12.17, 11.97, and 11.81 mSv for the four protocols, respectively. The corresponding lifetime attributable risks estimated for 5-year-old U.S. boys and girls were 0.14%-0.20% and 0.43%-0.60%, respectively, and for 5-year-old Hong Kong boys and girls were 0.22%-0.33% and 0.61%-0.85%. In relation to the total cancer incidence (baseline cancer incidence plus lifetime attributable risk), lifetime attributable risk from radiation exposure contributed up to 0.99% and 3.51% for Hong Kong boys and girls and up to 0.46% and 1.57% for U.S. boys and girls. CONCLUSION. Our results suggest that radiation dose and cancer risk of CT coronary angiography to pediatric patients are not negligible, more so in Hong Kong children than in U.S. children. Therefore, these examinations should be well justified clinically. © American Roentgen Ray Society.en_US
dc.languageengen_US
dc.publisherAmerican Roentgen Ray Society. The Journal's web site is located at http://www.arrs.org/scriptcontent/ajr/index.cfmen_US
dc.relation.ispartofAmerican Journal of Roentgenologyen_US
dc.subject.meshBody Burdenen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCoronary Angiography - Methods - Statistics & Numerical Dataen_US
dc.subject.meshElectrocardiography - Methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Rateen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMaleen_US
dc.subject.meshModels, Cardiovascularen_US
dc.subject.meshNeoplasms, Radiation-Induced - Epidemiologyen_US
dc.subject.meshPhantoms, Imagingen_US
dc.subject.meshRadiation Dosageen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshUnited States - Epidemiologyen_US
dc.titlePediatric 64-MDCT coronary angiography with ECG-modulated tube current: Radiation dose and cancer risken_US
dc.typeArticleen_US
dc.identifier.emailMak, HKF:makkf@hkucc.hku.hken_US
dc.identifier.emailKhong, PL:plkhong@hkucc.hku.hken_US
dc.identifier.authorityMak, HKF=rp00533en_US
dc.identifier.authorityKhong, PL=rp00467en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.2214/AJR.08.1920en_US
dc.identifier.pmid19620454-
dc.identifier.scopuseid_2-s2.0-68149158910en_US
dc.identifier.hkuros161071-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68149158910&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume193en_US
dc.identifier.issue2en_US
dc.identifier.spage539en_US
dc.identifier.epage544en_US
dc.identifier.isiWOS:000268148600035-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHuang, B=36087446500en_US
dc.identifier.scopusauthoridLaw, MWM=8663654000en_US
dc.identifier.scopusauthoridMak, HKF=7004699149en_US
dc.identifier.scopusauthoridKwok, SPF=34977020700en_US
dc.identifier.scopusauthoridKhong, PL=7006693233en_US
dc.identifier.citeulike9422015-

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