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Conference Paper: Cyp26b1 mediates differential regulation of RA signaling in neural progenitor populations along the anteriorposterior axis of the adult spinal cord

TitleCyp26b1 mediates differential regulation of RA signaling in neural progenitor populations along the anteriorposterior axis of the adult spinal cord
Authors
Issue Date2011
Citation
The 2011 Meeting of the Days of Molecular Medicine (DMM), Hong Kong, 10-12 November 2011. How to Cite?
AbstractNeural stem cells from the adult subventricular zone (SVZ) are highly heterogeneous, with their position of origin being a key factor in determining the neuronal subtype they can give rise to. Whether this diversity extends to other regions in the adult CNS has not been demonstrated. In vitro studies with directed neuronal differentiation of ES cells suggest that subtype specification may be regulated by the positional identity present in the ES‐derived cell, since altering the positional identity leads to corresponding changes in motor neuron subtype. This limited plasticity suggests the position identity of the original stem cell source is a critical factor for the generation of the desired neuronal subtype. The adult spinal cord consists of endogenous stem/progenitor cells which are …
DescriptionDMM 2011 entitled: Re-engineering Regenerative Medicine
Poster Session - Neural Regeneration: no. 64
Persistent Identifierhttp://hdl.handle.net/10722/149199

 

DC FieldValueLanguage
dc.contributor.authorLeung, Cen_US
dc.contributor.authorChan, SCLen_US
dc.contributor.authorTsang, SLen_US
dc.contributor.authorWu, Wen_US
dc.contributor.authorSham, MHen_US
dc.date.accessioned2012-06-22T06:29:50Z-
dc.date.available2012-06-22T06:29:50Z-
dc.date.issued2011en_US
dc.identifier.citationThe 2011 Meeting of the Days of Molecular Medicine (DMM), Hong Kong, 10-12 November 2011.en_US
dc.identifier.urihttp://hdl.handle.net/10722/149199-
dc.descriptionDMM 2011 entitled: Re-engineering Regenerative Medicine-
dc.descriptionPoster Session - Neural Regeneration: no. 64-
dc.description.abstractNeural stem cells from the adult subventricular zone (SVZ) are highly heterogeneous, with their position of origin being a key factor in determining the neuronal subtype they can give rise to. Whether this diversity extends to other regions in the adult CNS has not been demonstrated. In vitro studies with directed neuronal differentiation of ES cells suggest that subtype specification may be regulated by the positional identity present in the ES‐derived cell, since altering the positional identity leads to corresponding changes in motor neuron subtype. This limited plasticity suggests the position identity of the original stem cell source is a critical factor for the generation of the desired neuronal subtype. The adult spinal cord consists of endogenous stem/progenitor cells which are …-
dc.languageengen_US
dc.relation.ispartofDay of Molecular Medicine Meeeting, DMM 2011en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleCyp26b1 mediates differential regulation of RA signaling in neural progenitor populations along the anteriorposterior axis of the adult spinal corden_US
dc.typeConference_Paperen_US
dc.identifier.emailTsang, SL: sltsang@hku.hken_US
dc.identifier.emailWu, W: wtwu@hkucc.hku.hken_US
dc.identifier.emailSham, MH: mhsham@hku.hken_US
dc.identifier.authorityWu, W=rp00419en_US
dc.identifier.authoritySham, MH=rp00380en_US
dc.description.naturepostprint-
dc.identifier.hkuros200426en_US

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