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Article: Simultaneous occurrence of diabetic glomerulosclerosis, IgA nephropathy, crescentic glomerulonephritis, and myeloperoxidase-antineutrophil cytoplasmic antibody seropositivity in a Chinese patient.

TitleSimultaneous occurrence of diabetic glomerulosclerosis, IgA nephropathy, crescentic glomerulonephritis, and myeloperoxidase-antineutrophil cytoplasmic antibody seropositivity in a Chinese patient.
Authors
Issue Date2002
Citation
American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation, 2002, v. 40 n. 4, p. E14 How to Cite?
AbstractWe report the case of a 72-year-old woman with a long-standing history of diabetes mellitus who presented with heavy proteinuria and rapid deterioration in renal function. She had a high titer of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA). The renal biopsy specimen revealed features of diabetic glomerulosclerosis, crescentic glomerulonephritis, and IgA nephropathy. Treatment with steroid and cyclophosphamide resulted in significant improvement in renal function and normalization of MPO-ANCA level. This case highlights the importance of having a high index of suspicion for coexisting glomerulonephritis in diabetic patients presenting with proteinuria. The clinical course of patients with diabetic glomerulosclerosis, IgA nephropathy, crescentic glomerulonephritis, and MPO-ANCA seropositivity seems to resemble that of ANCA-associated, rapidly progressive glomerulonephritis and is potentially amenable to aggressive immunosuppressive therapy. Copyright 2002 by the National Kidney Foundation, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/148411
ISSN
2015 SCImago Journal Rankings: 2.313
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLui, SLen_HK
dc.contributor.authorChan, KWen_HK
dc.contributor.authorYip, PSen_HK
dc.contributor.authorChan, TMen_HK
dc.contributor.authorLai, KNen_HK
dc.contributor.authorLo, WKen_HK
dc.date.accessioned2012-05-29T06:12:48Z-
dc.date.available2012-05-29T06:12:48Z-
dc.date.issued2002en_HK
dc.identifier.citationAmerican Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation, 2002, v. 40 n. 4, p. E14en_HK
dc.identifier.issn1523-6838en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148411-
dc.description.abstractWe report the case of a 72-year-old woman with a long-standing history of diabetes mellitus who presented with heavy proteinuria and rapid deterioration in renal function. She had a high titer of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA). The renal biopsy specimen revealed features of diabetic glomerulosclerosis, crescentic glomerulonephritis, and IgA nephropathy. Treatment with steroid and cyclophosphamide resulted in significant improvement in renal function and normalization of MPO-ANCA level. This case highlights the importance of having a high index of suspicion for coexisting glomerulonephritis in diabetic patients presenting with proteinuria. The clinical course of patients with diabetic glomerulosclerosis, IgA nephropathy, crescentic glomerulonephritis, and MPO-ANCA seropositivity seems to resemble that of ANCA-associated, rapidly progressive glomerulonephritis and is potentially amenable to aggressive immunosuppressive therapy. Copyright 2002 by the National Kidney Foundation, Inc.en_HK
dc.languageengen_US
dc.relation.ispartofAmerican journal of kidney diseases : the official journal of the National Kidney Foundationen_HK
dc.subject.meshAgeden_US
dc.subject.meshAnti-Glomerular Basement Membrane Disease - Blood - Complications - Drug Therapy - Enzymologyen_US
dc.subject.meshAntibodies, Antineutrophil Cytoplasmic - Blood - Metabolismen_US
dc.subject.meshChina - Ethnologyen_US
dc.subject.meshDiabetic Nephropathies - Complications - Drug Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlomerulonephritis, Iga - Complications - Drug Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshPeroxidase - Immunologyen_US
dc.titleSimultaneous occurrence of diabetic glomerulosclerosis, IgA nephropathy, crescentic glomerulonephritis, and myeloperoxidase-antineutrophil cytoplasmic antibody seropositivity in a Chinese patient.en_HK
dc.typeArticleen_HK
dc.identifier.emailChan, KW: hrmtckw@hku.hken_HK
dc.identifier.emailChan, TM: dtmchan@hku.hken_HK
dc.identifier.emailLai, KN: knlai@hku.hken_HK
dc.identifier.authorityChan, KW=rp00330en_HK
dc.identifier.authorityChan, TM=rp00394en_HK
dc.identifier.authorityLai, KN=rp00324en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid12324935-
dc.identifier.scopuseid_2-s2.0-19044364480en_HK
dc.identifier.hkuros79057-
dc.identifier.volume40en_HK
dc.identifier.issue4en_HK
dc.identifier.spageE14en_HK
dc.identifier.epageE14en_HK
dc.identifier.isiWOS:000178386000038-
dc.identifier.scopusauthoridLui, SL=7102379130en_HK
dc.identifier.scopusauthoridChan, KW=16444133100en_HK
dc.identifier.scopusauthoridYip, PS=14219904600en_HK
dc.identifier.scopusauthoridChan, TM=7402687700en_HK
dc.identifier.scopusauthoridLai, KN=7402135706en_HK
dc.identifier.scopusauthoridLo, WK=7201502414en_HK

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