File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Liver transplantation in children: The experience of Queen Mary Hospital, Hong Kong

TitleLiver transplantation in children: The experience of Queen Mary Hospital, Hong Kong
Authors
Keywordsbiliary atresia
Living-related liver transplantation
microvascular anastomosis
reduced-size liver transplantation
Issue Date1997
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurg
Citation
Journal Of Pediatric Surgery, 1997, v. 32 n. 1, p. 80-83 How to Cite?
Abstract
Seven living-related liver transplants (LRLT) and two reduced-size liver transplants (RSLT) were performed on eight children who suffered from end- stage liver disease, having previously undergone one to three abdominal operations. Their ages at initial transplantation ranged from 8 months to 11 years (mean 35 months, median 12 months). Excluding the two older children aged 7 and 11 years, respectively, the rest of the children weighed 6 to 9.5 kg (mean 7.3 kg) at the time of the initial transplantation. Seven left lateral segments (S2 + 3) and two left lobes (S2 + 3 + 4) were used; of these the smallest graft had a graft-to-recipient body weight ratio of 0.9%. The volunteer living donors were four mothers, two fathers and one sister who were selected after medical and psychiatric evaluations, and their suitability was confirmed by hematological, biochemical, and radiological criteria. During a follow-up period of 3 to 30 months, all eight children are alive and well with normal liver function, one of them having undergone a retransplant LRLT because of hepatitis of undetermined etiology following a RSLT 1.5 years earlier. All seven donors had an uneventful postoperative course and were discharged on day 4 to 7 postoperatively. They have all resumed normal day-to-day activities. There were no complications in the donor group. A variety of complications occurred in the recipients, all of which were overcome. Operating microscope was used to perform all the arterial anastomoses using microvascular techniques. This method has proven to be a major factor in preventing arterial thrombosis even with the smallest of arterial anastomosis where a 1.5-mm diameter recipient artery was anastomosed to a 2.5-mm diameter donor hepatic artery.
Persistent Identifierhttp://hdl.handle.net/10722/148389
ISSN
2013 Impact Factor: 1.311
2013 SCImago Journal Rankings: 0.811
ISI Accession Number ID
References

 

Author Affiliations
  1. The University of Hong Kong
DC FieldValueLanguage
dc.contributor.authorSaing, Hen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorChan, KLen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorMya, GHen_HK
dc.contributor.authorTsoi, NSen_HK
dc.contributor.authorYuen, KYen_HK
dc.contributor.authorNg, IOLen_HK
dc.contributor.authorLo, JWRen_HK
dc.contributor.authorChau, MTen_HK
dc.contributor.authorTsoi, WKen_HK
dc.contributor.authorChan, Jen_HK
dc.contributor.authorWong, Jen_HK
dc.date.accessioned2012-05-29T06:12:40Z-
dc.date.available2012-05-29T06:12:40Z-
dc.date.issued1997en_HK
dc.identifier.citationJournal Of Pediatric Surgery, 1997, v. 32 n. 1, p. 80-83en_HK
dc.identifier.issn0022-3468en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148389-
dc.description.abstractSeven living-related liver transplants (LRLT) and two reduced-size liver transplants (RSLT) were performed on eight children who suffered from end- stage liver disease, having previously undergone one to three abdominal operations. Their ages at initial transplantation ranged from 8 months to 11 years (mean 35 months, median 12 months). Excluding the two older children aged 7 and 11 years, respectively, the rest of the children weighed 6 to 9.5 kg (mean 7.3 kg) at the time of the initial transplantation. Seven left lateral segments (S2 + 3) and two left lobes (S2 + 3 + 4) were used; of these the smallest graft had a graft-to-recipient body weight ratio of 0.9%. The volunteer living donors were four mothers, two fathers and one sister who were selected after medical and psychiatric evaluations, and their suitability was confirmed by hematological, biochemical, and radiological criteria. During a follow-up period of 3 to 30 months, all eight children are alive and well with normal liver function, one of them having undergone a retransplant LRLT because of hepatitis of undetermined etiology following a RSLT 1.5 years earlier. All seven donors had an uneventful postoperative course and were discharged on day 4 to 7 postoperatively. They have all resumed normal day-to-day activities. There were no complications in the donor group. A variety of complications occurred in the recipients, all of which were overcome. Operating microscope was used to perform all the arterial anastomoses using microvascular techniques. This method has proven to be a major factor in preventing arterial thrombosis even with the smallest of arterial anastomosis where a 1.5-mm diameter recipient artery was anastomosed to a 2.5-mm diameter donor hepatic artery.en_HK
dc.languageengen_US
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurgen_HK
dc.relation.ispartofJournal of Pediatric Surgeryen_HK
dc.subjectbiliary atresiaen_HK
dc.subjectLiving-related liver transplantationen_HK
dc.subjectmicrovascular anastomosisen_HK
dc.subjectreduced-size liver transplantationen_HK
dc.subject.meshActivities Of Daily Livingen_US
dc.subject.meshAnastomosis, Surgical - Methodsen_US
dc.subject.meshBody Weighten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshGraft Survivalen_US
dc.subject.meshHepatic Artery - Surgeryen_US
dc.subject.meshHepatitis - Surgeryen_US
dc.subject.meshHistocompatibilityen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshLiver Failure - Surgeryen_US
dc.subject.meshLiver Transplantation - Adverse Effects - Methods - Pathology - Statistics & Numerical Dataen_US
dc.subject.meshLiving Donors - Classificationen_US
dc.subject.meshMaleen_US
dc.subject.meshMicrosurgeryen_US
dc.subject.meshOrgan Sizeen_US
dc.subject.meshPostoperative Complications - Prevention & Control - Surgeryen_US
dc.subject.meshReoperationen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshThrombosis - Prevention & Controlen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVascular Surgical Procedures - Methodsen_US
dc.titleLiver transplantation in children: The experience of Queen Mary Hospital, Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailYuen, KY: kyyuen@hkucc.hku.hken_HK
dc.identifier.emailNg, IOL: iolng@hku.hken_HK
dc.identifier.emailWong, J: jwong@hkucc.hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.identifier.authorityNg, IOL=rp00335en_HK
dc.identifier.authorityWong, J=rp00322en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0022-3468(97)90100-7en_HK
dc.identifier.pmid9021576en_HK
dc.identifier.scopuseid_2-s2.0-12644305893en_HK
dc.identifier.hkuros24212-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-12644305893&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue1en_HK
dc.identifier.spage80en_HK
dc.identifier.epage83en_HK
dc.identifier.isiWOS:A1997WE27500023-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSaing, H=7005715754en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridChan, KL=37004089600en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridMya, GH=6602928992en_HK
dc.identifier.scopusauthoridTsoi, NS=6603693887en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.scopusauthoridNg, IOL=7102753722en_HK
dc.identifier.scopusauthoridLo, JWR=16935769800en_HK
dc.identifier.scopusauthoridChau, MT=7006073758en_HK
dc.identifier.scopusauthoridTsoi, WK=7005719683en_HK
dc.identifier.scopusauthoridChan, J=7403287057en_HK
dc.identifier.scopusauthoridWong, J=8049324500en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats