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Article: Inflammatory pseudotumor of the liver: Report of four cases and review of the literature

TitleInflammatory pseudotumor of the liver: Report of four cases and review of the literature
Authors
Issue Date1993
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ajsp.com
Citation
American Journal Of Surgical Pathology, 1993, v. 17 n. 3, p. 231-238 How to Cite?
AbstractIn this report, we describe four cases of inflammatory pseudotumor of the liver and review the literature of this disease entity. The age of our patients ranged from 31 to 35 years (mean, 33 years). Two had fever, weight loss, and upper abdominal pain. The other had an incidental 1-cm nodule in the liver found during left hemihepatectomy for recurrent attacks of cholangitis. The preoperative clinical diagnoses in the former two cases were hepatocellular carcinoma. The patients had unremarkable recovery after resection. Grossly, the tumors showed a variegated appearance with areas of hemorrhage and necrosis and resembling hepatocellular carcinoma. Microscopically, the tumors were composed of a polyclonal population of reactive plasma cells and abundant plump spindle cells. The latter expressed vimentin but stained negatively for actin, desmin, and myosin. Ultrastructurally, these plump spindle cells showed features of fibroblastic differentiation. Forty-seven cases of inflammatory pseudotumor of the liver have been reported, 35 in males and 12 in females (male-to-female ratio of 2.9). The patients had a wide age range (10 months to 83 years; mean, 37 years). The most common symptoms were fever, upper abdominal pain and a space-occupying lesion in the liver. Surgical excision was curative. A few patients responded to antibiotic and steroid treatment. The recognition and distinction of this entity from hepatocellular carcinoma and other malignant tumors is particularly important in order to avoid unnecessary extensive surgery.
Persistent Identifierhttp://hdl.handle.net/10722/147987
ISSN
2015 Impact Factor: 4.951
2015 SCImago Journal Rankings: 2.393
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorShek, TWHen_US
dc.contributor.authorNg, IOLen_US
dc.contributor.authorChan, KWen_US
dc.date.accessioned2012-05-29T06:10:14Z-
dc.date.available2012-05-29T06:10:14Z-
dc.date.issued1993en_US
dc.identifier.citationAmerican Journal Of Surgical Pathology, 1993, v. 17 n. 3, p. 231-238en_US
dc.identifier.issn0147-5185en_US
dc.identifier.urihttp://hdl.handle.net/10722/147987-
dc.description.abstractIn this report, we describe four cases of inflammatory pseudotumor of the liver and review the literature of this disease entity. The age of our patients ranged from 31 to 35 years (mean, 33 years). Two had fever, weight loss, and upper abdominal pain. The other had an incidental 1-cm nodule in the liver found during left hemihepatectomy for recurrent attacks of cholangitis. The preoperative clinical diagnoses in the former two cases were hepatocellular carcinoma. The patients had unremarkable recovery after resection. Grossly, the tumors showed a variegated appearance with areas of hemorrhage and necrosis and resembling hepatocellular carcinoma. Microscopically, the tumors were composed of a polyclonal population of reactive plasma cells and abundant plump spindle cells. The latter expressed vimentin but stained negatively for actin, desmin, and myosin. Ultrastructurally, these plump spindle cells showed features of fibroblastic differentiation. Forty-seven cases of inflammatory pseudotumor of the liver have been reported, 35 in males and 12 in females (male-to-female ratio of 2.9). The patients had a wide age range (10 months to 83 years; mean, 37 years). The most common symptoms were fever, upper abdominal pain and a space-occupying lesion in the liver. Surgical excision was curative. A few patients responded to antibiotic and steroid treatment. The recognition and distinction of this entity from hepatocellular carcinoma and other malignant tumors is particularly important in order to avoid unnecessary extensive surgery.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ajsp.comen_US
dc.relation.ispartofAmerican Journal of Surgical Pathologyen_US
dc.subject.meshAdulten_US
dc.subject.meshCarcinoma, Hepatocellular - Diagnosisen_US
dc.subject.meshDiagnosis, Differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshGranuloma, Plasma Cell - Pathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshLiver - Pathology - Ultrastructureen_US
dc.subject.meshLiver Diseases - Pathologyen_US
dc.subject.meshLiver Neoplasms - Diagnosisen_US
dc.subject.meshMaleen_US
dc.titleInflammatory pseudotumor of the liver: Report of four cases and review of the literatureen_US
dc.typeArticleen_US
dc.identifier.emailNg, IOL:iolng@hkucc.hku.hken_US
dc.identifier.emailChan, KW:hrmtckw@hku.hken_US
dc.identifier.authorityNg, IOL=rp00335en_US
dc.identifier.authorityChan, KW=rp00330en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8382011-
dc.identifier.scopuseid_2-s2.0-0027499197en_US
dc.identifier.volume17en_US
dc.identifier.issue3en_US
dc.identifier.spage231en_US
dc.identifier.epage238en_US
dc.identifier.isiWOS:A1993KN93700003-
dc.publisher.placeUnited Statesen_US

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