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Article: Placental site trophoblastic tumor: With features between an exaggerated placental site reaction and a placental site trophoblasic tumor

TitlePlacental site trophoblastic tumor: With features between an exaggerated placental site reaction and a placental site trophoblasic tumor
Authors
Issue Date1990
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.intjgynpathology.com
Citation
International Journal Of Gynecological Pathology, 1990, v. 9 n. 2, p. 170-177 How to Cite?
AbstractChorionic villi, whose presence in cases of trophoblastic disease is normally used to exclude both a choriocarcinoma and placental site trophoblastic tumor (PSTT), were present in the initial uterine curettage specimen of a trophoblastic tumor. The lesion shared morphologic features of both an exaggerated placental site reaction and a PSTT. There was infiltration of the posterior wall of the uterus by small clusters and isolated cells which had a prominent affinity for vessels and resembled a usual placental bed reaction. There was, however, deep involvement of myometrium with extension to the cervix, and the condition persisted for 5 months after uterine evacuation. Because different treatment is entailed, identification of this lesion as a tumor of nonvillous trophoblast is also of great importance in a region where the more usual forms of trophoblastic disease represent a declining but not infrequent event. When products of gestation are examined, the possibility of a PSTT should be considered and the clinician alerted if there is a suggestion of excessive intermediate trophoblastic activity, regardless of the presence of chorionic villi. While this may result in the unnecessary followup of some cases, it would permit, with the aid of serial β-hCG and HPL levels, the earlier detection of PSTTs.
Persistent Identifierhttp://hdl.handle.net/10722/147868
ISSN
2015 Impact Factor: 1.437
2015 SCImago Journal Rankings: 0.723
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorCollins, RJen_HK
dc.contributor.authorNgan, HYSen_HK
dc.contributor.authorWong, LCen_HK
dc.date.accessioned2012-05-29T06:09:39Z-
dc.date.available2012-05-29T06:09:39Z-
dc.date.issued1990en_HK
dc.identifier.citationInternational Journal Of Gynecological Pathology, 1990, v. 9 n. 2, p. 170-177en_HK
dc.identifier.issn0277-1691en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147868-
dc.description.abstractChorionic villi, whose presence in cases of trophoblastic disease is normally used to exclude both a choriocarcinoma and placental site trophoblastic tumor (PSTT), were present in the initial uterine curettage specimen of a trophoblastic tumor. The lesion shared morphologic features of both an exaggerated placental site reaction and a PSTT. There was infiltration of the posterior wall of the uterus by small clusters and isolated cells which had a prominent affinity for vessels and resembled a usual placental bed reaction. There was, however, deep involvement of myometrium with extension to the cervix, and the condition persisted for 5 months after uterine evacuation. Because different treatment is entailed, identification of this lesion as a tumor of nonvillous trophoblast is also of great importance in a region where the more usual forms of trophoblastic disease represent a declining but not infrequent event. When products of gestation are examined, the possibility of a PSTT should be considered and the clinician alerted if there is a suggestion of excessive intermediate trophoblastic activity, regardless of the presence of chorionic villi. While this may result in the unnecessary followup of some cases, it would permit, with the aid of serial β-hCG and HPL levels, the earlier detection of PSTTs.en_HK
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.intjgynpathology.comen_HK
dc.relation.ispartofInternational Journal of Gynecological Pathologyen_HK
dc.subject.meshAdulten_US
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols - Therapeutic Useen_US
dc.subject.meshChoriocarcinoma - Pathology - Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHysterectomyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshUterine Neoplasms - Pathology - Therapyen_US
dc.titlePlacental site trophoblastic tumor: With features between an exaggerated placental site reaction and a placental site trophoblasic tumoren_HK
dc.typeArticleen_HK
dc.identifier.emailCollins, RJ:rcollins@hkucc.hku.hken_HK
dc.identifier.emailNgan, HYS:hysngan@hkucc.hku.hken_HK
dc.identifier.authorityCollins, RJ=rp00251en_HK
dc.identifier.authorityNgan, HYS=rp00346en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2332271-
dc.identifier.scopuseid_2-s2.0-0025335419en_HK
dc.identifier.volume9en_HK
dc.identifier.issue2en_HK
dc.identifier.spage170en_HK
dc.identifier.epage177en_HK
dc.identifier.isiWOS:A1990CW91100008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCollins, RJ=7403350455en_HK
dc.identifier.scopusauthoridNgan, HYS=34571944100en_HK
dc.identifier.scopusauthoridWong, LC=7402092003en_HK

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