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Article: Sex-related differences and thyroid hormone regulation of vasoactive intestinal peptide gene expression in the rat brain and pituitary

TitleSex-related differences and thyroid hormone regulation of vasoactive intestinal peptide gene expression in the rat brain and pituitary
Authors
KeywordsAnterior pituitary
Brain
Gene expression
Rat
Sexual dimorphism
Thyroid hormone
Vasoactive intestinal peptide
Issue Date1990
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainres
Citation
Brain Research, 1990, v. 526 n. 1, p. 135-137 How to Cite?
AbstractTo determine the effects of hypothyroidism and sexual dimorphism on the gene expression of vasoactive intestinal peptide (VIP) in the rat brain, VIP mRNA levels were measured in the cerebral cortex, hypothalamus and anterior pituitary of control and hypothyroid (thionamide-treated) rats. A tissue-specific increase in VIP mRNA level was observed in the hypothyroid pituitary. In addition, higher levels of VIP mRNA were found in the pituitaries of male rats suggesting a sex-related difference in VIP gene expression. Similar differences were not observed in the cortex or hypothalamus.
Persistent Identifierhttp://hdl.handle.net/10722/147854
ISSN
2015 Impact Factor: 2.561
2015 SCImago Journal Rankings: 1.351
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, KSLen_HK
dc.contributor.authorSrivastava, Gen_HK
dc.date.accessioned2012-05-29T06:09:34Z-
dc.date.available2012-05-29T06:09:34Z-
dc.date.issued1990en_HK
dc.identifier.citationBrain Research, 1990, v. 526 n. 1, p. 135-137en_HK
dc.identifier.issn0006-8993en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147854-
dc.description.abstractTo determine the effects of hypothyroidism and sexual dimorphism on the gene expression of vasoactive intestinal peptide (VIP) in the rat brain, VIP mRNA levels were measured in the cerebral cortex, hypothalamus and anterior pituitary of control and hypothyroid (thionamide-treated) rats. A tissue-specific increase in VIP mRNA level was observed in the hypothyroid pituitary. In addition, higher levels of VIP mRNA were found in the pituitaries of male rats suggesting a sex-related difference in VIP gene expression. Similar differences were not observed in the cortex or hypothalamus.en_HK
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainresen_HK
dc.relation.ispartofBrain Researchen_HK
dc.subjectAnterior pituitaryen_HK
dc.subjectBrainen_HK
dc.subjectGene expressionen_HK
dc.subjectRaten_HK
dc.subjectSexual dimorphismen_HK
dc.subjectThyroid hormoneen_HK
dc.subjectVasoactive intestinal peptideen_HK
dc.subject.meshAnimalsen_US
dc.subject.meshBrain - Physiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGene Expression Regulation - Physiologyen_US
dc.subject.meshHypothyroidism - Physiopathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshOrgan Specificity - Physiologyen_US
dc.subject.meshPituitary Gland, Anterior - Physiologyen_US
dc.subject.meshRna, Messenger - Metabolismen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Inbred Strainsen_US
dc.subject.meshSex Characteristicsen_US
dc.subject.meshThyroid Hormones - Physiologyen_US
dc.subject.meshVasoactive Intestinal Peptide - Geneticsen_US
dc.titleSex-related differences and thyroid hormone regulation of vasoactive intestinal peptide gene expression in the rat brain and pituitaryen_HK
dc.typeArticleen_HK
dc.identifier.emailLam, KSL:ksllam@hku.hken_HK
dc.identifier.emailSrivastava, G:gopesh@pathology.hku.hken_HK
dc.identifier.authorityLam, KSL=rp00343en_HK
dc.identifier.authoritySrivastava, G=rp00365en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0006-8993(90)90259-Een_HK
dc.identifier.pmid2078813-
dc.identifier.scopuseid_2-s2.0-0025076642en_HK
dc.identifier.volume526en_HK
dc.identifier.issue1en_HK
dc.identifier.spage135en_HK
dc.identifier.epage137en_HK
dc.identifier.isiWOS:A1990DZ70300018-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLam, KSL=8082870600en_HK
dc.identifier.scopusauthoridSrivastava, G=7202242238en_HK

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