Granted Patent: High-Throughput Diagnostic Assay For The Human Virus Causing Severe Acute Respiratory Syndrome (Sars)

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TitleHigh-Throughput Diagnostic Assay For The Human Virus Causing Severe Acute Respiratory Syndrome (Sars)
Granted PatentUS 7547512
Granted Date2009-06-16
Priority Date2004-03-24 US 11/807807
2003-03-24 US 10/457031P
2003-03-26 US 10/457730P
2003-04-02 US 10/459931P
2003-04-03 US 10/460357P
2003-04-08 US 10/461265P
2003-04-14 US 10/462805P
2003-04-23 US 10/464886P
2003-04-25 US 10/465738P
2003-05-14 US 10/470935P
InventorsChan, Kwok Hung
Guan, Yi
Leung, Frederick C C
Nicholls, John Malcolm
Peiris, Joseph Sriyal Malik
Poon, Leo Lit Man
Yuen, Kwok Yung
CitationUS Patent 7547512. Washington, DC: US Patent and Trademark Office (USPTO), 2009 [How to Cite?]
AbstractThe Present Invention Relates To A High-Throughput Diagnostic Assay For The Virus Causing Severe Acute Respiratory Syndrome (Sars) In Humans ("Hsars Virus"). In Particular, The Invention Relates To A High-Throughput Reverse Transcription-Pcr Diagnostic Test For Sars Associated Coronavirus (Sars-Cov). The Present Assay Is A Rapid, Reliable Assay Which Can Be Used For Diagnosis And Monitoring The Spread Of Sars And Is Based On The Nucleotide Sequences Of The N (Nucleocapsid)-Gene Of The Hsars Virus. The Present Method Eliminates False Negative Results And Provides Increased Sensitivity For The Assay. The Invention Also Discloses The S (Spike)-Gene Of The Hsars Virus. The Invention Further Relates To The Deduced Amino Acid Sequences Of The N-Gene And S-Gene Products Of The Hsars Virus And To The Use Of The N-Gene And S-Gene Products In Diagnostic Methods.; The Invention Further Encompasses Diagnostic Assays And Kits Comprising Antibodies Generated Against The N-Gene Or S-Gene Product.
ReferencesUS 2004265796 (A1) 2004-12-30

US 7582740 (B2) 2009-09-01

WO 02057302 (A2) 2002-07-25

WO 02057302 (A3) 2002-12-27

WO 02057302 (A8) 2003-11-13
DC Field
Value
dc.contributor.inventorChan, Kwok Hung
dc.contributor.inventorGuan, Yi
dc.contributor.inventorLeung, Frederick C C
dc.contributor.inventorNicholls, John Malcolm
dc.contributor.inventorPeiris, Joseph Sriyal Malik
dc.contributor.inventorPoon, Leo Lit Man
dc.contributor.inventorYuen, Kwok Yung
dc.date.accessioned2011-10-19T06:32:46Z
patents.date.application2004-03-24
dc.date.available2011-10-19T06:32:46Z
patents.date.granted2009-06-16
patents.date.priority2004-03-24 US 11/807807
patents.date.priority2003-03-24 US 10/457031P
patents.date.priority2003-03-26 US 10/457730P
patents.date.priority2003-04-02 US 10/459931P
patents.date.priority2003-04-03 US 10/460357P
patents.date.priority2003-04-08 US 10/461265P
patents.date.priority2003-04-14 US 10/462805P
patents.date.priority2003-04-23 US 10/464886P
patents.date.priority2003-04-25 US 10/465738P
patents.date.priority2003-05-14 US 10/470935P
patents.date.publication2005-08-18
dc.description.abstractThe Present Invention Relates To A High-Throughput Diagnostic Assay For The Virus Causing Severe Acute Respiratory Syndrome (Sars) In Humans ("Hsars Virus"). In Particular, The Invention Relates To A High-Throughput Reverse Transcription-Pcr Diagnostic Test For Sars Associated Coronavirus (Sars-Cov). The Present Assay Is A Rapid, Reliable Assay Which Can Be Used For Diagnosis And Monitoring The Spread Of Sars And Is Based On The Nucleotide Sequences Of The N (Nucleocapsid)-Gene Of The Hsars Virus. The Present Method Eliminates False Negative Results And Provides Increased Sensitivity For The Assay. The Invention Also Discloses The S (Spike)-Gene Of The Hsars Virus. The Invention Further Relates To The Deduced Amino Acid Sequences Of The N-Gene And S-Gene Products Of The Hsars Virus And To The Use Of The N-Gene And S-Gene Products In Diagnostic Methods.; The Invention Further Encompasses Diagnostic Assays And Kits Comprising Antibodies Generated Against The N-Gene Or S-Gene Product.
patents.description.assigneeUniv Hong Kong [Cn]
patents.description.ccUS
patents.description.countryUnited States of America
patents.description.kindB2
dc.description.naturepublished_or_final_version
patents.identifier.applicationUS 11/807807
dc.identifier.citationUS Patent 7547512. Washington, DC: US Patent and Trademark Office (USPTO), 2009 [How to Cite?]
patents.identifier.grantedUS 7547512
patents.identifier.hkutechidMicro-2003-00161
patents.identifier.publicationUS 20050181357
dc.identifier.urihttp://hdl.handle.net/10722/142154
patents.relation.familyCN 1761745 (A) 2006-04-19
patents.relation.familyCN 100543132 (C) 2009-09-23
patents.relation.familyCN 1768074 (A) 2006-05-03
patents.relation.familyCN 1768140 (A) 2006-05-03
patents.relation.familyCN 101186920 (A) 2008-05-28
patents.relation.familyCN 102021147 (A) 2011-04-20
patents.relation.familyUS 2005009009 (A1) 2005-01-13
patents.relation.familyUS 7267942 (B2) 2007-09-11
patents.relation.familyUS 2008069838 (A1) 2008-03-20
patents.relation.familyUS 7375202 (B2) 2008-05-20
patents.relation.familyUS 2005181357 (A1) 2005-08-18
patents.relation.familyUS 7547512 (B2) 2009-06-16
patents.relation.familyUS 2010080824 (A1) 2010-04-01
patents.relation.familyUS 7785775 (B2) 2010-08-31
patents.relation.familyUS 2010184019 (A1) 2010-07-22
patents.relation.familyUS 2010285457 (A1) 2010-11-11
patents.relation.familyWO 2004085455 (A1) 2004-10-07
patents.relation.familyWO 2004085633 (A1) 2004-10-07
patents.relation.familyWO 2004085650 (A1) 2004-10-07
dc.relation.isreferencedbyUS 2010009343 (A1) 2010-01-14
dc.relation.isreferencedbyUS 8097419 (B2) 2012-01-17
dc.relation.isreferencedbyUS 7776521 (B1) 2010-08-17
dc.relation.isreferencedbyWO 2006025791 (A1) 2006-03-09
dc.relation.isreferencedbyUS 2005095618 (A1) 2005-05-05
dc.relation.isreferencedbyUS 7371525 (B2) 2008-05-13
dc.relation.isreferencedbyUS 2007105193 (A1) 2007-05-10
dc.relation.isreferencedbyUS 8080642 (B2) 2011-12-20
dc.relation.referencesUS 2004265796 (A1) 2004-12-30
dc.relation.referencesUS 7582740 (B2) 2009-09-01
dc.relation.referencesWO 02057302 (A2) 2002-07-25
dc.relation.referencesWO 02057302 (A3) 2002-12-27
dc.relation.referencesWO 02057302 (A8) 2003-11-13
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents
dc.titleHigh-Throughput Diagnostic Assay For The Human Virus Causing Severe Acute Respiratory Syndrome (Sars)
dc.typePatent
patents.typePatent_granted