File Download
  Patent History
  • Application
    US 10/408501 2003-04-07
  • Publication
    US 20030224424 2003-12-04
  • Granted
    US 7198898 2007-04-03
Supplementary

granted patent: PHOX2B polymorphisms as Hirschsprung's Disease diagnostic markers and methods based thereon

TitlePHOX2B polymorphisms as Hirschsprung's Disease diagnostic markers and methods based thereon
Granted PatentUS 7198898
Granted Date2007-04-03
Priority Date2003-04-07 US 10/408501
2002-04-08 US 10/370968P
Inventors
Issue Date2007
Citation
US Patent 7198898. Washington, DC: US Patent and Trademark Office (USPTO), 2007 How to Cite?
Abstract
The Invention Relates Generally To Polymorphisms Or Mutations Of The Phox2b Gene. More Particularly, The Invention Relates To Polymorphisms Or Mutations Of The Phox2b Gene That Are Responsible For The Disease Hirschsprung's Disease (Hscr), Which Is A Neural Crest-Associated Developmental Disorder. Specifically, The Invention Relates To The Detection Of A Single Base-Pair Polymorphism In The Phox2b Gene That Is Associated With Hscr. The Invention Also Relates To Methods And Kits For Screening For Carriers Of Mutations Of The Phox2b Gene And The Diagnosis Of Increased Risk Of Hscr. The Invention Further Relates To Diagnosing Predisposition Or Susceptibility To Increased Risk Of Developing Hscr By Screening For The Presence Of A Polymorphism Associated With Hscr.; The Invention Also Relates To Compositions For Screening For The Polymorphism And Treatment Choices For Patients Having The Polymorphism Of The Present Invention. The Invention Further Relates To Providing Polymorphisms In The Phox2b Gene For Forensic Use And In Paternity Test. The Invention Also Relates To Screening Assays And Therapeutic And Prophylactic Methods.
Persistent Identifierhttp://hdl.handle.net/10722/142076

 

DC FieldValueLanguage
dc.date.accessioned2011-10-19T06:29:15Z-
dc.date.available2011-10-19T06:29:15Z-
dc.date.issued2007-
dc.identifier.citationUS Patent 7198898. Washington, DC: US Patent and Trademark Office (USPTO), 2007en_HK
dc.identifier.urihttp://hdl.handle.net/10722/142076-
dc.description.abstractThe Invention Relates Generally To Polymorphisms Or Mutations Of The Phox2b Gene. More Particularly, The Invention Relates To Polymorphisms Or Mutations Of The Phox2b Gene That Are Responsible For The Disease Hirschsprung's Disease (Hscr), Which Is A Neural Crest-Associated Developmental Disorder. Specifically, The Invention Relates To The Detection Of A Single Base-Pair Polymorphism In The Phox2b Gene That Is Associated With Hscr. The Invention Also Relates To Methods And Kits For Screening For Carriers Of Mutations Of The Phox2b Gene And The Diagnosis Of Increased Risk Of Hscr. The Invention Further Relates To Diagnosing Predisposition Or Susceptibility To Increased Risk Of Developing Hscr By Screening For The Presence Of A Polymorphism Associated With Hscr.; The Invention Also Relates To Compositions For Screening For The Polymorphism And Treatment Choices For Patients Having The Polymorphism Of The Present Invention. The Invention Further Relates To Providing Polymorphisms In The Phox2b Gene For Forensic Use And In Paternity Test. The Invention Also Relates To Screening Assays And Therapeutic And Prophylactic Methods.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titlePHOX2B polymorphisms as Hirschsprung's Disease diagnostic markers and methods based thereonen_HK
dc.typePatenten_US
dc.identifier.emailChen, Ling Sze Benedict:en_US
dc.identifier.emailGarcia-barcelo, Maria-mercedes:mmgarcia@hkucc.hku.hken_US
dc.identifier.emailLui, Vincent Chi Hang:vchlui@hkucc.hku.hken_US
dc.identifier.emailSham, Mai Har:mhsham@hkucc.hku.hken_US
dc.identifier.emailTam, Paul Kwong Hang:paultam@hkucc.hku.hken_US
dc.identifier.authorityGarcia-barcelo, Maria-mercedes=rp00445en_US
dc.identifier.authorityLui, Vincent Chi Hang=rp00363en_US
dc.identifier.authoritySham, Mai Har=rp00380en_US
dc.identifier.authorityTam, Paul Kwong Hang=rp00060en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros187747-
dc.identifier.hkuros187748-
dc.contributor.inventorGarcia-Barcelo, MMen_US
dc.contributor.inventorSham, MHen_US
dc.contributor.inventorTam, PKHen_US
dc.contributor.inventorLui, VCHen_US
dc.contributor.inventorChen, BLSen_US
patents.identifier.applicationUS 10/408501en_HK
patents.identifier.grantedUS 7198898en_HK
patents.description.assigneeUniv Hong Kong [Hk]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2003-12-04en_HK
patents.date.granted2007-04-03en_HK
patents.identifier.hkutechidSurg-2002-00076en_US
patents.date.application2003-04-07en_HK
patents.date.priority2003-04-07 US 10/408501en_HK
patents.date.priority2002-04-08 US 10/370968Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20030224424en_HK
patents.relation.familyAU 2003218601 (A1) 2003-10-27en_HK
patents.relation.familyUS 2003224424 (A1) 2003-12-04en_HK
patents.relation.familyUS 7198898 (B2) 2007-04-03en_HK
patents.relation.familyWO 03087359 (A1) 2003-10-23en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats