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Book Chapter: Adiponectin and chronic liver diseases: an update
| Title | Adiponectin and chronic liver diseases: an update |
|---|---|
| Authors | |
| Issue Date | 2012 |
| Publisher | NOVA Publishers |
| Citation | Adiponectin and chronic liver diseases: an update. In Yamaguchi, M (Ed.), Adiponectin: production, regulation and roles in disease, p. 49-80. New York, NY: NOVA Publishers, 2012 How to Cite? |
| Abstract | Adiponectin is an oligomeric adipokine possessing a myriad of beneficial activities against obesity-related medical complications. Abnormal circulating adiponectin levels are closely associated with the development of chronic liver diseases, including non-alcoholic hepatic steatosis, steatohepatitis, fibrosis and cirrhosis, as well as hepatocellular carcinoma. The hepatoprotective functions of adiponectin have been demonstrated by numerous clinical, pharmacological and genetic investigations. This review will provide an update on the pathophysiological role of adiponectin in liver and the molecular mechanisms underlying its metabolic and anti-inflammatory activities. The potentials for adiponectin-based therapeutic interventions for chronic liver diseases will also be discussed. |
| Persistent Identifier | http://hdl.handle.net/10722/141461 |
| ISBN |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Wang, Y | en_US |
| dc.contributor.author | Lam, KSL | en_US |
| dc.contributor.author | Xu, A | en_US |
| dc.date.accessioned | 2011-09-23T06:37:14Z | - |
| dc.date.available | 2011-09-23T06:37:14Z | - |
| dc.date.issued | 2012 | en_US |
| dc.identifier.citation | Adiponectin and chronic liver diseases: an update. In Yamaguchi, M (Ed.), Adiponectin: production, regulation and roles in disease, p. 49-80. New York, NY: NOVA Publishers, 2012 | en_US |
| dc.identifier.isbn | 9781619421653 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/141461 | - |
| dc.description.abstract | Adiponectin is an oligomeric adipokine possessing a myriad of beneficial activities against obesity-related medical complications. Abnormal circulating adiponectin levels are closely associated with the development of chronic liver diseases, including non-alcoholic hepatic steatosis, steatohepatitis, fibrosis and cirrhosis, as well as hepatocellular carcinoma. The hepatoprotective functions of adiponectin have been demonstrated by numerous clinical, pharmacological and genetic investigations. This review will provide an update on the pathophysiological role of adiponectin in liver and the molecular mechanisms underlying its metabolic and anti-inflammatory activities. The potentials for adiponectin-based therapeutic interventions for chronic liver diseases will also be discussed. | - |
| dc.language | eng | en_US |
| dc.publisher | NOVA Publishers | en_US |
| dc.relation.ispartof | Adiponectin: production, regulation and roles in disease | en_US |
| dc.title | Adiponectin and chronic liver diseases: an update | en_US |
| dc.type | Book_Chapter | en_US |
| dc.identifier.email | Wang, Y: yuwanghk@hku.hk | en_US |
| dc.identifier.email | Lam, KSL: ksllam@hku.hk | en_US |
| dc.identifier.email | Xu, A: amxu@hkucc.hku.hk | en_US |
| dc.identifier.authority | Wang, Y=rp00239 | en_US |
| dc.identifier.authority | Lam, KSL=rp00343 | en_US |
| dc.identifier.authority | Xu, A=rp00485 | en_US |
| dc.identifier.hkuros | 195697 | en_US |
| dc.identifier.hkuros | 219902 | - |
| dc.identifier.spage | 49 | - |
| dc.identifier.epage | 80 | - |
| dc.publisher.place | New York, NY | - |
| dc.customcontrol.immutable | yiu 130628 | - |