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Conference Paper: The diffusion pattern of healthy and myelopathic cervical spinal cord: a template-based analysis

TitleThe diffusion pattern of healthy and myelopathic cervical spinal cord: a template-based analysis
Authors
Issue Date2011
PublisherBlackwell Publishing, Inc.
Citation
The 34th Annual Meeting of the The American Society of Neuroimaging (ASN 2011), Fort Myers, FL., 20-23 January 2011. Journal of Neuroimaging, 2011, v. 21 n. 1, p. 99, abstract no. 20 How to Cite?
AbstractINTRODUCTION: Diffusion tensor imaging (DTI) permits the detection of water molecular diffusion movement inside spinal cord parenchyma. This study aimed to evaluate the diffusion patterns in myelopathic cord under the external and/or internal pressures. PATIENTS (OR MATERIALS) AND METHODS: A total of 45 volunteers were recruited in this study with informed consent including 25 healthy subjects (46 ± 17), 1 syringomyelia patient (54 yrs), 13 cervical spondylotic myelopathy (CSM) patients (63 ± 12 yrs), 6 traumatic central cord syndrome (TCCS) patients (61 ± 21 yrs). The axial diffusion MR images of cervical spinal cord were taken from C1 to C7 using pulsed gradient spin-echo-echo-planar imaging sequence with a 3T MR system. The regions of interest were defined based on a template to cover the ventral, lateral, and posterior column of white matter as well as gray matter in FA maps of spinal cord, then FA values were generated for comparison. RESULTS: In healthy cord, FA values in posterior and lateral columns were significantly higher than ventral column and gray matter. Under slow and progressive external compression in CSM, FA of the posterolateral columns were mostly affected; in traumatic cases, FA of the ventral column and gray matter were more severely disturbed. In one case of syringomyelia, the lateral column and gray matter were involved. CONCLUSION: The diffusion patterns of myelopathic cord were specific to various types of external and/or internal pressures. A template-based analysis might delineate the injury patterns of myelopathic cord and contribute to the in-depth understanding of the underlying pathomechanism.
DescriptionPages.96-101 of this journal issue contain 2011 ASN Abstracts
Persistent Identifierhttp://hdl.handle.net/10722/135996
ISSN
2015 Impact Factor: 1.625
2015 SCImago Journal Rankings: 0.778

 

DC FieldValueLanguage
dc.contributor.authorWen, Cen_US
dc.contributor.authorHu, Yen_US
dc.contributor.authorCui, Jen_US
dc.contributor.authorMak, KCen_US
dc.contributor.authorMak, HKFen_US
dc.contributor.authorLuk, KDK-
dc.date.accessioned2011-07-27T02:01:04Z-
dc.date.available2011-07-27T02:01:04Z-
dc.date.issued2011en_US
dc.identifier.citationThe 34th Annual Meeting of the The American Society of Neuroimaging (ASN 2011), Fort Myers, FL., 20-23 January 2011. Journal of Neuroimaging, 2011, v. 21 n. 1, p. 99, abstract no. 20en_US
dc.identifier.issn1051-2284-
dc.identifier.urihttp://hdl.handle.net/10722/135996-
dc.descriptionPages.96-101 of this journal issue contain 2011 ASN Abstracts-
dc.description.abstractINTRODUCTION: Diffusion tensor imaging (DTI) permits the detection of water molecular diffusion movement inside spinal cord parenchyma. This study aimed to evaluate the diffusion patterns in myelopathic cord under the external and/or internal pressures. PATIENTS (OR MATERIALS) AND METHODS: A total of 45 volunteers were recruited in this study with informed consent including 25 healthy subjects (46 ± 17), 1 syringomyelia patient (54 yrs), 13 cervical spondylotic myelopathy (CSM) patients (63 ± 12 yrs), 6 traumatic central cord syndrome (TCCS) patients (61 ± 21 yrs). The axial diffusion MR images of cervical spinal cord were taken from C1 to C7 using pulsed gradient spin-echo-echo-planar imaging sequence with a 3T MR system. The regions of interest were defined based on a template to cover the ventral, lateral, and posterior column of white matter as well as gray matter in FA maps of spinal cord, then FA values were generated for comparison. RESULTS: In healthy cord, FA values in posterior and lateral columns were significantly higher than ventral column and gray matter. Under slow and progressive external compression in CSM, FA of the posterolateral columns were mostly affected; in traumatic cases, FA of the ventral column and gray matter were more severely disturbed. In one case of syringomyelia, the lateral column and gray matter were involved. CONCLUSION: The diffusion patterns of myelopathic cord were specific to various types of external and/or internal pressures. A template-based analysis might delineate the injury patterns of myelopathic cord and contribute to the in-depth understanding of the underlying pathomechanism.-
dc.languageengen_US
dc.publisherBlackwell Publishing, Inc.-
dc.relation.ispartofJournal of Neuroimagingen_US
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.titleThe diffusion pattern of healthy and myelopathic cervical spinal cord: a template-based analysisen_US
dc.typeConference_Paperen_US
dc.identifier.emailWen, C: paulwen@hku.hken_US
dc.identifier.emailHu, Y: yhud@hku.hken_US
dc.identifier.emailMak, KC: kincmak@hku.hken_US
dc.identifier.emailMak, HKF: makkf@hkucc.hku.hken_US
dc.identifier.emailLuk, KDK: hcm21000@hku.hk-
dc.identifier.authorityHu, Y=rp00432en_US
dc.identifier.doi10.1111/j.1552-6569.2010.00558.x-
dc.identifier.hkuros188856en_US
dc.identifier.volume21en_US
dc.identifier.issue1en_US
dc.identifier.spage99en_US
dc.identifier.epage99en_US
dc.publisher.placeUnited States-

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