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Article: Pulmonary valve replacement after surgical repair of tetralogy of Fallot

TitlePulmonary valve replacement after surgical repair of tetralogy of Fallot
Authors
KeywordsHeart valve prosthesis implantation
Pulmonary valve insufficiency
Tetralogy of fallot
Treatment outcome
Issue Date2010
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
Citation
Hong Kong Medical Journal, 2010, v. 16 n. 1, p. 26-30 How to Cite?
AbstractObjective: To evaluate the results of pulmonary valve replacement in patients with severe pulmonary regurgitation after tetralogy of Fallot repair in Hong Kong. Design: Retrospective review. Setting: University teaching hospital, Hong Kong. Patients: Consecutive patients undergoing pulmonary valve replacement after repair of tetralogy of Fallot between August 2002 and December 2008. Main outcome measures: Magnetic resonance imaging of right ventricular volume and cardiopulmonary exercise test data before and after the operation were documented and compared. Results: Over a 6-year period, 16 patients underwent pulmonary valve replacement for severe pulmonary regurgitation after prior complete repair for tetralogy of Fallot. There was no in-hospital mortality. The mean time interval between the initial repair and pulmonary valve replacement was 19 (standard deviation, 9) years. In three patients, the indication for pulmonary valve replacement was symptomatic severe pulmonary regurgitation, and asymptomatic progressive right ventricular dilatation in the remaining 13 patients. After pulmonary valve replacement, there was a significant decrease in the mean indexed right ventricular end-diastolic volume from 173 (standard deviation, 44) mL/m2 to 103 (19) mL/m2 (P=0.043). After the operation, there was also a tendency for improvement of the right ventricular ejection fraction and the maximum oxygen consumption: from 42% (standard deviation, 9%) to 47% (6%) [P=0.173], and 27 (4) mL/kg/min to 29 (4) mL/kg/min (P=0.208), respectively. Conclusion: Pulmonary valve replacement for severe pulmonary regurgitation after tetralogy of Fallot repair is a safe procedure. However, the indications for such an operation in asymptomatic patients remain controversial. Further studies are required to better delineate the timing of pulmonary valve replacement in this patient group.
Persistent Identifierhttp://hdl.handle.net/10722/130955
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279
References

 

DC FieldValueLanguage
dc.contributor.authorTsang, FHFen_HK
dc.contributor.authorLi, Xen_HK
dc.contributor.authorCheung, YFen_HK
dc.contributor.authorChau, KTen_HK
dc.contributor.authorCheng, LCen_HK
dc.date.accessioned2011-01-17T04:54:41Z-
dc.date.available2011-01-17T04:54:41Z-
dc.date.issued2010en_HK
dc.identifier.citationHong Kong Medical Journal, 2010, v. 16 n. 1, p. 26-30en_HK
dc.identifier.issn1024-2708en_HK
dc.identifier.urihttp://hdl.handle.net/10722/130955-
dc.description.abstractObjective: To evaluate the results of pulmonary valve replacement in patients with severe pulmonary regurgitation after tetralogy of Fallot repair in Hong Kong. Design: Retrospective review. Setting: University teaching hospital, Hong Kong. Patients: Consecutive patients undergoing pulmonary valve replacement after repair of tetralogy of Fallot between August 2002 and December 2008. Main outcome measures: Magnetic resonance imaging of right ventricular volume and cardiopulmonary exercise test data before and after the operation were documented and compared. Results: Over a 6-year period, 16 patients underwent pulmonary valve replacement for severe pulmonary regurgitation after prior complete repair for tetralogy of Fallot. There was no in-hospital mortality. The mean time interval between the initial repair and pulmonary valve replacement was 19 (standard deviation, 9) years. In three patients, the indication for pulmonary valve replacement was symptomatic severe pulmonary regurgitation, and asymptomatic progressive right ventricular dilatation in the remaining 13 patients. After pulmonary valve replacement, there was a significant decrease in the mean indexed right ventricular end-diastolic volume from 173 (standard deviation, 44) mL/m2 to 103 (19) mL/m2 (P=0.043). After the operation, there was also a tendency for improvement of the right ventricular ejection fraction and the maximum oxygen consumption: from 42% (standard deviation, 9%) to 47% (6%) [P=0.173], and 27 (4) mL/kg/min to 29 (4) mL/kg/min (P=0.208), respectively. Conclusion: Pulmonary valve replacement for severe pulmonary regurgitation after tetralogy of Fallot repair is a safe procedure. However, the indications for such an operation in asymptomatic patients remain controversial. Further studies are required to better delineate the timing of pulmonary valve replacement in this patient group.en_HK
dc.languageeng-
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.htmlen_HK
dc.relation.ispartofHong Kong Medical Journalen_HK
dc.subjectHeart valve prosthesis implantationen_HK
dc.subjectPulmonary valve insufficiencyen_HK
dc.subjectTetralogy of falloten_HK
dc.subjectTreatment outcomeen_HK
dc.subject.meshElectrocardiography-
dc.subject.meshHeart Valve Prosthesis Implantation - methods-
dc.subject.meshPulmonary Valve - surgery-
dc.subject.meshPulmonary Valve Insufficiency - surgery-
dc.subject.meshTetralogy of Fallot - surgery-
dc.titlePulmonary valve replacement after surgical repair of tetralogy of Falloten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1024-2708&volume=16&issue=1&spage=26&epage=30&date=2010&atitle=Pulmonary+valve+replacement+after+surgical+repair+of+tetralogy+of+Fallot-
dc.identifier.emailLi, X: lixin08@hku.hken_HK
dc.identifier.emailCheung, YF: xfcheung@hku.hken_HK
dc.identifier.authorityLi, X=rp00266en_HK
dc.identifier.authorityCheung, YF=rp00382en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid20124570-
dc.identifier.scopuseid_2-s2.0-76149119104en_HK
dc.identifier.hkuros168874-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-76149119104&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue1en_HK
dc.identifier.spage26en_HK
dc.identifier.epage30en_HK
dc.publisher.placeHong Kongen_HK
dc.identifier.scopusauthoridTsang, FHF=7003264965en_HK
dc.identifier.scopusauthoridLi, X=36068374600en_HK
dc.identifier.scopusauthoridCheung, YF=7202111067en_HK
dc.identifier.scopusauthoridChau, KT=35975776800en_HK
dc.identifier.scopusauthoridCheng, LC=9533935800en_HK

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