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Article: Retrospective review on anomalous left coronary artery from pulmonary artery
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TitleRetrospective review on anomalous left coronary artery from pulmonary artery
 
AuthorsKo, LY1
Chau, AKT1
Yung, TC1
Cheung, YF1
Lun, KS1
 
KeywordsAnomalous left coronary artery from pulmonary artery
Diagnosis
Presentation
Surgical outcomes
 
Issue Date2010
 
PublisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
 
CitationHong Kong Journal Of Paediatrics, 2010, v. 15 n. 1, p. 12-18 [How to Cite?]
 
AbstractAnomalous left coronary artery from pulmonary artery (ALCAPA) is a rare but important congenital coronary anomaly. Patients with ALCAPA typically present with paroxysms of crying, pallor, diaphoresis, agitation and heart failure in infancy due to myocardial ischaemia. Clinical course thus very much depends on the presence and development of collateral circulation. We report the clinical presentation and method of diagnosis of ALCAPA in Chinese children in Hong Kong. We also study their long term outcomes after surgery and compare local data with overseas results. Early diagnosis and correction are important to avoid development of or progression of mitral regurgitation, which appeared to be associated with lower chance of requiring mitral valve annuloplasty/replacement. The majority of patients in Hong Kong presents as infantile form with heart failure, mitral regurgitation and dilated cardiomyopathy. Typical ECG changes are present in 5 cases (55.6%). Echocardiography confirms the diagnosis in 3 cases (33.3%). The remaining patients require cardiac catheterization to confirm the diagnosis. Early diagnosis therefore relies on a high index of suspicion. The diagnosis of ALCAPA should be considered as differential diagnosis of mitral regurgitation, endocardial fibroelastosis and dilated cardiomyopathy. Cardiac catheterization is warranted in doubtful cases. Long-term survival and outcome after surgical treatment appear to be favourable with good functional status. Residual lesions occur in 4 (44.4%) patients and re-operation on the mitral valve is required in 1 (11.1%) patient. Our local results are comparable to overseas reports.
 
DescriptionOpen Access Journal
 
ISSN1013-9923
2013 Impact Factor: 0.106
2013 SCImago Journal Rankings: 0.126
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorKo, LY
 
dc.contributor.authorChau, AKT
 
dc.contributor.authorYung, TC
 
dc.contributor.authorCheung, YF
 
dc.contributor.authorLun, KS
 
dc.date.accessioned2011-01-07T09:16:08Z
 
dc.date.available2011-01-07T09:16:08Z
 
dc.date.issued2010
 
dc.description.abstractAnomalous left coronary artery from pulmonary artery (ALCAPA) is a rare but important congenital coronary anomaly. Patients with ALCAPA typically present with paroxysms of crying, pallor, diaphoresis, agitation and heart failure in infancy due to myocardial ischaemia. Clinical course thus very much depends on the presence and development of collateral circulation. We report the clinical presentation and method of diagnosis of ALCAPA in Chinese children in Hong Kong. We also study their long term outcomes after surgery and compare local data with overseas results. Early diagnosis and correction are important to avoid development of or progression of mitral regurgitation, which appeared to be associated with lower chance of requiring mitral valve annuloplasty/replacement. The majority of patients in Hong Kong presents as infantile form with heart failure, mitral regurgitation and dilated cardiomyopathy. Typical ECG changes are present in 5 cases (55.6%). Echocardiography confirms the diagnosis in 3 cases (33.3%). The remaining patients require cardiac catheterization to confirm the diagnosis. Early diagnosis therefore relies on a high index of suspicion. The diagnosis of ALCAPA should be considered as differential diagnosis of mitral regurgitation, endocardial fibroelastosis and dilated cardiomyopathy. Cardiac catheterization is warranted in doubtful cases. Long-term survival and outcome after surgical treatment appear to be favourable with good functional status. Residual lesions occur in 4 (44.4%) patients and re-operation on the mitral valve is required in 1 (11.1%) patient. Our local results are comparable to overseas reports.
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionOpen Access Journal
 
dc.identifier.citationHong Kong Journal Of Paediatrics, 2010, v. 15 n. 1, p. 12-18 [How to Cite?]
 
dc.identifier.epage18
 
dc.identifier.hkuros168664
 
dc.identifier.issn1013-9923
2013 Impact Factor: 0.106
2013 SCImago Journal Rankings: 0.126
 
dc.identifier.issue1
 
dc.identifier.openurl
 
dc.identifier.scopuseid_2-s2.0-77449110803
 
dc.identifier.spage12
 
dc.identifier.urihttp://hdl.handle.net/10722/130949
 
dc.identifier.volume15
 
dc.languageeng
 
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
 
dc.publisher.placeHong Kong
 
dc.relation.ispartofHong Kong Journal of Paediatrics
 
dc.relation.referencesReferences in Scopus
 
dc.rightsDOAJ
 
dc.subjectAnomalous left coronary artery from pulmonary artery
 
dc.subjectDiagnosis
 
dc.subjectPresentation
 
dc.subjectSurgical outcomes
 
dc.titleRetrospective review on anomalous left coronary artery from pulmonary artery
 
dc.typeArticle
 
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Author Affiliations
  1. Queen Mary Hospital Hong Kong