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Conference Paper: In vivo proton MRS of liver in an experimental liver fibrosis model
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TitleIn vivo proton MRS of liver in an experimental liver fibrosis model
 
AuthorsCheung, JSC
Fan, SJ
Gao, DS
Chan, KWY
Chow, AMK
Man, K
Wu, EX
 
Issue Date2010
 
CitationThe ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. [How to Cite?]
 
AbstractCarbon tetrachloride (CCl4) intoxication is a well-characterized, reproducible and the most commonly used experimental model of liver fibrosis. Proton magnetic resonance spectroscopy (1H MRS) can provide insights into in vivo liver metabolism noninvasively, yet detailed in vivo MRS study of CCl4-induced liver fibrosis model has been limited. The aim of this study was to characterize early metabolic changes in CCl4-induced liver fibrosis in rodents by means of single-voxel 1H MRS. Our experimental results demonstrated that 1H MRS at high field may be valuable in characterizing metabolic changes in liver, in particular those related to lipid and glutamine metabolism, after CCl4 insult.
 
DescriptionPosters - MRS - Body Applications: No. 4733
 
DC FieldValue
dc.contributor.authorCheung, JSC
 
dc.contributor.authorFan, SJ
 
dc.contributor.authorGao, DS
 
dc.contributor.authorChan, KWY
 
dc.contributor.authorChow, AMK
 
dc.contributor.authorMan, K
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2010-12-23T08:40:37Z
 
dc.date.available2010-12-23T08:40:37Z
 
dc.date.issued2010
 
dc.description.abstractCarbon tetrachloride (CCl4) intoxication is a well-characterized, reproducible and the most commonly used experimental model of liver fibrosis. Proton magnetic resonance spectroscopy (1H MRS) can provide insights into in vivo liver metabolism noninvasively, yet detailed in vivo MRS study of CCl4-induced liver fibrosis model has been limited. The aim of this study was to characterize early metabolic changes in CCl4-induced liver fibrosis in rodents by means of single-voxel 1H MRS. Our experimental results demonstrated that 1H MRS at high field may be valuable in characterizing metabolic changes in liver, in particular those related to lipid and glutamine metabolism, after CCl4 insult.
 
dc.descriptionPosters - MRS - Body Applications: No. 4733
 
dc.identifier.citationThe ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. [How to Cite?]
 
dc.identifier.hkuros178241
 
dc.identifier.urihttp://hdl.handle.net/10722/129639
 
dc.languageeng
 
dc.relation.ispartofISMRM-ESMRMB Joint Annual Meeting
 
dc.titleIn vivo proton MRS of liver in an experimental liver fibrosis model
 
dc.typeConference_Paper
 
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<item><contributor.author>Cheung, JSC</contributor.author>
<contributor.author>Fan, SJ</contributor.author>
<contributor.author>Gao, DS</contributor.author>
<contributor.author>Chan, KWY</contributor.author>
<contributor.author>Chow, AMK</contributor.author>
<contributor.author>Man, K</contributor.author>
<contributor.author>Wu, EX</contributor.author>
<date.accessioned>2010-12-23T08:40:37Z</date.accessioned>
<date.available>2010-12-23T08:40:37Z</date.available>
<date.issued>2010</date.issued>
<identifier.citation>The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010.</identifier.citation>
<identifier.uri>http://hdl.handle.net/10722/129639</identifier.uri>
<description>Posters - MRS - Body Applications: No. 4733</description>
<description.abstract>Carbon tetrachloride (CCl4) intoxication is a well-characterized, reproducible and the most commonly used experimental model of liver fibrosis. Proton magnetic resonance spectroscopy (1H MRS) can provide insights into in vivo liver metabolism noninvasively, yet detailed in vivo MRS study of CCl4-induced liver fibrosis model has been limited. The aim of this study was to characterize early metabolic changes in CCl4-induced liver fibrosis in rodents by means of single-voxel 1H MRS. Our experimental results demonstrated that 1H MRS at high field may be valuable in characterizing metabolic changes in liver, in particular those related to lipid and glutamine metabolism, after CCl4 insult.</description.abstract>
<language>eng</language>
<relation.ispartof>ISMRM-ESMRMB Joint Annual Meeting</relation.ispartof>
<title>In vivo proton MRS of liver in an experimental liver fibrosis model</title>
<type>Conference_Paper</type>
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