File Download

There are no files associated with this item.

Conference Paper: In vivo proton MRS of liver in an experimental liver fibrosis model

TitleIn vivo proton MRS of liver in an experimental liver fibrosis model
Authors
Issue Date2010
Citation
The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. How to Cite?
AbstractCarbon tetrachloride (CCl4) intoxication is a well-characterized, reproducible and the most commonly used experimental model of liver fibrosis. Proton magnetic resonance spectroscopy (1H MRS) can provide insights into in vivo liver metabolism noninvasively, yet detailed in vivo MRS study of CCl4-induced liver fibrosis model has been limited. The aim of this study was to characterize early metabolic changes in CCl4-induced liver fibrosis in rodents by means of single-voxel 1H MRS. Our experimental results demonstrated that 1H MRS at high field may be valuable in characterizing metabolic changes in liver, in particular those related to lipid and glutamine metabolism, after CCl4 insult.
DescriptionPosters - MRS - Body Applications: No. 4733
Persistent Identifierhttp://hdl.handle.net/10722/129639

 

DC FieldValueLanguage
dc.contributor.authorCheung, JSCen_US
dc.contributor.authorFan, SJen_US
dc.contributor.authorGao, DSen_US
dc.contributor.authorChan, KWYen_US
dc.contributor.authorChow, AMKen_US
dc.contributor.authorMan, Ken_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2010-12-23T08:40:37Z-
dc.date.available2010-12-23T08:40:37Z-
dc.date.issued2010en_US
dc.identifier.citationThe ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010.en_US
dc.identifier.urihttp://hdl.handle.net/10722/129639-
dc.descriptionPosters - MRS - Body Applications: No. 4733-
dc.description.abstractCarbon tetrachloride (CCl4) intoxication is a well-characterized, reproducible and the most commonly used experimental model of liver fibrosis. Proton magnetic resonance spectroscopy (1H MRS) can provide insights into in vivo liver metabolism noninvasively, yet detailed in vivo MRS study of CCl4-induced liver fibrosis model has been limited. The aim of this study was to characterize early metabolic changes in CCl4-induced liver fibrosis in rodents by means of single-voxel 1H MRS. Our experimental results demonstrated that 1H MRS at high field may be valuable in characterizing metabolic changes in liver, in particular those related to lipid and glutamine metabolism, after CCl4 insult.-
dc.languageengen_US
dc.relation.ispartofISMRM-ESMRMB Joint Annual Meeting-
dc.titleIn vivo proton MRS of liver in an experimental liver fibrosis modelen_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, KWY: kannie@graduate.hku.hken_US
dc.identifier.emailChow, AMK: aprilcmk@hkusua.hku.hk-
dc.identifier.emailMan, K: kwanman@hkucc.hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.hkuros178241en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats