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Article: Systolic-diastolic coupling of myocardial deformation of the left ventricle in children with left ventricular noncompaction

TitleSystolic-diastolic coupling of myocardial deformation of the left ventricle in children with left ventricular noncompaction
Authors
KeywordsLeft ventricular noncompaction
Myocardial deformation
Issue Date2010
PublisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327
Citation
Heart And Vessels, 2010, v. 25 n. 6, p. 493-499 How to Cite?
AbstractDisruption of the myocardial architecture in left ventricular noncompaction (LVNC) may alter myocardial deformation. We evaluated LV myocardial deformation and tested the hypothesis that tight systolic-diastolic coupling occurs in LVNC. Longitudinal and circumferential strain and strain rates (SRs) as determined by speckle tracking echocardiography in nine children aged 5.6 ± 5.5 years was compared with those in nine controls. Left ventricular systolic myocardial deformation parameters were correlated with ejection fraction and indices of diastolic deformation. Compared with controls, patients had lower global LV systolic longitudinal strain (P = 0.008), systolic SR (P = 0.05) and early diastolic SR (P < 0.001). Similarly, LV systolic circumferential strain (base, P = 0.04; papillary muscle level, P = 0.01; apex, P = 0.04), systolic SR (base, P = 0.04) and early diastolic SR (papillary muscle level, P = 0.004, apex, P = 0.02) were lower in patients than in controls. Among patients, the LV ejection fraction correlated with global longitudinal systolic strain and SR and circumferential systolic strain and SR at all levels (all P < 0.05). Positive correlations existed between early diastolic and systolic SRs in corresponding dimensions (longitudinal r = 0.80, P = 0.01; circumferential at base, r = 0.91, P = 0.001; papillary muscle level, r = 0.96, P < 0.001; apex r = 0.98, P = <0.001). In conclusion, LV myocardial deformation is reduced in the longitudinal and circumferential dimensions and manifests tight systolic-diastolic coupling in children with LVNC. © 2010 Springer.
Persistent Identifierhttp://hdl.handle.net/10722/129325
ISSN
2015 Impact Factor: 2.293
2015 SCImago Journal Rankings: 0.709
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKoh, Cen_HK
dc.contributor.authorHong, WJen_HK
dc.contributor.authorWong, SJen_HK
dc.contributor.authorCheung, YFen_HK
dc.date.accessioned2010-12-23T08:35:20Z-
dc.date.available2010-12-23T08:35:20Z-
dc.date.issued2010en_HK
dc.identifier.citationHeart And Vessels, 2010, v. 25 n. 6, p. 493-499en_HK
dc.identifier.issn0910-8327en_HK
dc.identifier.urihttp://hdl.handle.net/10722/129325-
dc.description.abstractDisruption of the myocardial architecture in left ventricular noncompaction (LVNC) may alter myocardial deformation. We evaluated LV myocardial deformation and tested the hypothesis that tight systolic-diastolic coupling occurs in LVNC. Longitudinal and circumferential strain and strain rates (SRs) as determined by speckle tracking echocardiography in nine children aged 5.6 ± 5.5 years was compared with those in nine controls. Left ventricular systolic myocardial deformation parameters were correlated with ejection fraction and indices of diastolic deformation. Compared with controls, patients had lower global LV systolic longitudinal strain (P = 0.008), systolic SR (P = 0.05) and early diastolic SR (P < 0.001). Similarly, LV systolic circumferential strain (base, P = 0.04; papillary muscle level, P = 0.01; apex, P = 0.04), systolic SR (base, P = 0.04) and early diastolic SR (papillary muscle level, P = 0.004, apex, P = 0.02) were lower in patients than in controls. Among patients, the LV ejection fraction correlated with global longitudinal systolic strain and SR and circumferential systolic strain and SR at all levels (all P < 0.05). Positive correlations existed between early diastolic and systolic SRs in corresponding dimensions (longitudinal r = 0.80, P = 0.01; circumferential at base, r = 0.91, P = 0.001; papillary muscle level, r = 0.96, P < 0.001; apex r = 0.98, P = <0.001). In conclusion, LV myocardial deformation is reduced in the longitudinal and circumferential dimensions and manifests tight systolic-diastolic coupling in children with LVNC. © 2010 Springer.en_HK
dc.languageengen_US
dc.publisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327en_HK
dc.relation.ispartofHeart and Vesselsen_HK
dc.subjectLeft ventricular noncompactionen_HK
dc.subjectMyocardial deformationen_HK
dc.titleSystolic-diastolic coupling of myocardial deformation of the left ventricle in children with left ventricular noncompactionen_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, YF:xfcheung@hku.hken_HK
dc.identifier.authorityCheung, YF=rp00382en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00380-010-0001-8en_HK
dc.identifier.pmid20878168en_HK
dc.identifier.scopuseid_2-s2.0-78549240183en_HK
dc.identifier.hkuros183298en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78549240183&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume25en_HK
dc.identifier.issue6en_HK
dc.identifier.spage493en_HK
dc.identifier.epage499en_HK
dc.identifier.isiWOS:000285211600006-
dc.publisher.placeJapanen_HK
dc.identifier.scopusauthoridKoh, C=26321638500en_HK
dc.identifier.scopusauthoridHong, WJ=14010481700en_HK
dc.identifier.scopusauthoridWong, SJ=25924109100en_HK
dc.identifier.scopusauthoridCheung, YF=7202111067en_HK
dc.identifier.citeulike7933363-

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