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Article: Functional role of ICAM-3 polymorphism in genetic susceptibility to SARS infection

TitleFunctional role of ICAM-3 polymorphism in genetic susceptibility to SARS infection
Authors
Khoo, USChan, KYChing, JCChan, VSIp, YCYam, LChu, CMLai, STSo, KMWong, TYChung, PHTam, PYip, SPSham, PLeung, GMLin, CLPeiris, JS
Issue Date2009
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
Citation
Hong Kong Medical Journal, 2009, v. 15 n. 5, suppl. 6, p. 26-29 How to Cite?
AbstractKey Messages 1. Severe acute respiratory syndrome (SARS) patients who are homozygous for intercellular adhesion molecule-3 (ICAM-3) Gly143 showed significant association with higher lactate dehydrogenase levels and lower total white blood cell counts on admission. 2. In vitro functional studies demonstrated low level binding of ICAM-3 to DC-SIGN and a wide variation in T-cell response of the wild-type ICAM-3 genotype.
Persistent Identifierhttp://hdl.handle.net/10722/126691
ISSN
1024-2708
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 0.261

 

DC FieldValueLanguage
dc.contributor.authorKhoo, USen_HK
dc.contributor.authorChan, KYen_HK
dc.contributor.authorChing, JCen_HK
dc.contributor.authorChan, VSen_HK
dc.contributor.authorIp, YCen_HK
dc.contributor.authorYam, Len_HK
dc.contributor.authorChu, CMen_HK
dc.contributor.authorLai, STen_HK
dc.contributor.authorSo, KMen_HK
dc.contributor.authorWong, TYen_HK
dc.contributor.authorChung, PHen_HK
dc.contributor.authorTam, Pen_HK
dc.contributor.authorYip, SPen_HK
dc.contributor.authorSham, Pen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorLin, CLen_HK
dc.contributor.authorPeiris, JSen_HK
dc.date.accessioned2010-10-31T12:42:58Z-
dc.date.available2010-10-31T12:42:58Z-
dc.date.issued2009en_HK
dc.identifier.citationHong Kong Medical Journal, 2009, v. 15 n. 5, suppl. 6, p. 26-29en_HK
dc.identifier.issn1024-2708en_HK
dc.identifier.urihttp://hdl.handle.net/10722/126691-
dc.description.abstractKey Messages 1. Severe acute respiratory syndrome (SARS) patients who are homozygous for intercellular adhesion molecule-3 (ICAM-3) Gly143 showed significant association with higher lactate dehydrogenase levels and lower total white blood cell counts on admission. 2. In vitro functional studies demonstrated low level binding of ICAM-3 to DC-SIGN and a wide variation in T-cell response of the wild-type ICAM-3 genotype.-
dc.languageengen_HK
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.htmlen_HK
dc.relation.ispartofHong Kong Medical Journalen_HK
dc.subject.meshAntigens, CD - genetics-
dc.subject.meshCell Adhesion Molecules - genetics - physiology-
dc.subject.meshGenetic Predisposition to Disease-
dc.subject.meshPolymorphism, Single Nucleotide-
dc.subject.meshSevere Acute Respiratory Syndrome - blood - genetics-
dc.titleFunctional role of ICAM-3 polymorphism in genetic susceptibility to SARS infectionen_HK
dc.typeArticleen_HK
dc.identifier.emailKhoo, US: uskhoo@hku.hken_HK
dc.identifier.emailChan, KY: kelvinc@pathology.hku.hken_HK
dc.identifier.emailChan, VS: sfvchan@hku.hken_HK
dc.identifier.emailTam, P: paultam@hku.hken_HK
dc.identifier.emailSham, P: pcsham@hku.hken_HK
dc.identifier.emailLeung, GM: gmleung@hku.hken_HK
dc.identifier.emailPeiris, JS: malik@hkucc.hku.hken_HK
dc.identifier.authorityKhoo, US=rp00362en_HK
dc.identifier.authorityChan, KY=rp00453en_HK
dc.identifier.authorityChan, VS=rp01459en_HK
dc.identifier.authorityTam, P=rp00060en_HK
dc.identifier.authoritySham, P=rp00459en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.identifier.authorityPeiris, JS=rp00410en_HK
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.pmid19801714-
dc.identifier.scopuseid_2-s2.0-74949115016en_HK
dc.identifier.hkuros174759en_HK
dc.identifier.hkuros320815-
dc.identifier.volume15en_HK
dc.identifier.issue5, suppl. 6-
dc.identifier.spage26en_HK
dc.identifier.epage29en_HK
dc.publisher.placeHong Kongen_HK
dc.identifier.scopusauthoridKhoo, US=7004195799en_HK
dc.identifier.scopusauthoridChan, KY=7406034195en_HK
dc.identifier.scopusauthoridChing, JC=15735635300en_HK
dc.identifier.scopusauthoridChan, VS=35200370000en_HK
dc.identifier.scopusauthoridIp, YC=7006740135en_HK
dc.identifier.scopusauthoridYam, L=7102764741en_HK
dc.identifier.scopusauthoridChu, CM=7404345558en_HK
dc.identifier.scopusauthoridLai, ST=7402937038en_HK
dc.identifier.scopusauthoridSo, KM=35325513300en_HK
dc.identifier.scopusauthoridWong, TY=55350855600en_HK
dc.identifier.scopusauthoridChung, PH=34568741300en_HK
dc.identifier.scopusauthoridTam, P=7202539421en_HK
dc.identifier.scopusauthoridYip, SP=7102133673en_HK
dc.identifier.scopusauthoridSham, P=34573429300en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.scopusauthoridLin, CL=37099293900en_HK
dc.identifier.scopusauthoridPeiris, JS=7005486823en_HK
dc.identifier.issnl1024-2708-

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