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- PMID: 20461128
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Article: Hepatitis B and Renal Disease
Title | Hepatitis B and Renal Disease |
---|---|
Authors | |
Keywords | Hepatitis B Kidney transplantation |
Issue Date | 2010 |
Publisher | Springer Healthcare. The Journal's web site is located at http://www.springerlink.com/content/1540-3416/ |
Citation | Current Hepatitis Reports, 2010, v. 9 n. 2, p. 99-105 How to Cite? |
Abstract | Glomerulonephritis is an important extrahepatic manifestation of chronic hepatitis B virus (HBV) infection. The uncommon occurrence, variability in renal histopathology, and heterogeneity in clinical course present challenges in clinical studies and have resulted in a relative paucity of data and uncertainty with regard to the optimal management of HBV-related glomerular diseases. The advent of nucleos(t)ide analogue medications that effectively suppress HBV replication has markedly altered the clinical outcomes of kidney transplant recipients with HBV infection, but the emergence of drug resistance is an escalating problem. This article reviews the recent knowledge of the pathogenesis and treatment of HBV-related membranous nephropathy, and discusses the management of hepatitis B in kidney transplant recipients, which is continuously evolving. © 2010 The Author(s). |
Persistent Identifier | http://hdl.handle.net/10722/124025 |
ISSN | |
PubMed Central ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chan, TM | en_HK |
dc.date.accessioned | 2010-10-19T04:34:07Z | - |
dc.date.available | 2010-10-19T04:34:07Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | Current Hepatitis Reports, 2010, v. 9 n. 2, p. 99-105 | en_HK |
dc.identifier.issn | 1540-3416 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/124025 | - |
dc.description.abstract | Glomerulonephritis is an important extrahepatic manifestation of chronic hepatitis B virus (HBV) infection. The uncommon occurrence, variability in renal histopathology, and heterogeneity in clinical course present challenges in clinical studies and have resulted in a relative paucity of data and uncertainty with regard to the optimal management of HBV-related glomerular diseases. The advent of nucleos(t)ide analogue medications that effectively suppress HBV replication has markedly altered the clinical outcomes of kidney transplant recipients with HBV infection, but the emergence of drug resistance is an escalating problem. This article reviews the recent knowledge of the pathogenesis and treatment of HBV-related membranous nephropathy, and discusses the management of hepatitis B in kidney transplant recipients, which is continuously evolving. © 2010 The Author(s). | en_HK |
dc.language | eng | en_HK |
dc.publisher | Springer Healthcare. The Journal's web site is located at http://www.springerlink.com/content/1540-3416/ | en_HK |
dc.relation.ispartof | Current Hepatitis Reports | en_HK |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.rights | The original publication is available at www.springerlink.com | en_HK |
dc.subject | Hepatitis B | en_HK |
dc.subject | Kidney transplantation | en_HK |
dc.title | Hepatitis B and Renal Disease | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Chan, TM:dtmchan@hku.hk | en_HK |
dc.identifier.authority | Chan, TM=rp00394 | en_HK |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1007/s11901-010-0042-6 | en_HK |
dc.identifier.pmid | 20461128 | - |
dc.identifier.pmcid | PMC2861764 | - |
dc.identifier.scopus | eid_2-s2.0-77955983326 | en_HK |
dc.identifier.hkuros | 178492 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77955983326&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 9 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 99 | en_HK |
dc.identifier.epage | 105 | en_HK |
dc.identifier.eissn | 1541-0706 | en_HK |
dc.publisher.place | United States | en_HK |
dc.description.other | Springer Open Choice, 01 Dec 2010 | - |
dc.identifier.scopusauthorid | Chan, TM=7402687700 | en_HK |
dc.identifier.citeulike | 7042908 | - |
dc.identifier.issnl | 1540-3416 | - |