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Article: Hepatitis B and Renal Disease

TitleHepatitis B and Renal Disease
Authors
KeywordsHepatitis B
Kidney transplantation
Issue Date2010
PublisherSpringer Healthcare. The Journal's web site is located at http://www.springerlink.com/content/1540-3416/
Citation
Current Hepatitis Reports, 2010, v. 9 n. 2, p. 99-105 How to Cite?
AbstractGlomerulonephritis is an important extrahepatic manifestation of chronic hepatitis B virus (HBV) infection. The uncommon occurrence, variability in renal histopathology, and heterogeneity in clinical course present challenges in clinical studies and have resulted in a relative paucity of data and uncertainty with regard to the optimal management of HBV-related glomerular diseases. The advent of nucleos(t)ide analogue medications that effectively suppress HBV replication has markedly altered the clinical outcomes of kidney transplant recipients with HBV infection, but the emergence of drug resistance is an escalating problem. This article reviews the recent knowledge of the pathogenesis and treatment of HBV-related membranous nephropathy, and discusses the management of hepatitis B in kidney transplant recipients, which is continuously evolving. © 2010 The Author(s).
Persistent Identifierhttp://hdl.handle.net/10722/124025
ISSN
2015 SCImago Journal Rankings: 0.215
PubMed Central ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, TMen_HK
dc.date.accessioned2010-10-19T04:34:07Z-
dc.date.available2010-10-19T04:34:07Z-
dc.date.issued2010en_HK
dc.identifier.citationCurrent Hepatitis Reports, 2010, v. 9 n. 2, p. 99-105en_HK
dc.identifier.issn1540-3416en_HK
dc.identifier.urihttp://hdl.handle.net/10722/124025-
dc.description.abstractGlomerulonephritis is an important extrahepatic manifestation of chronic hepatitis B virus (HBV) infection. The uncommon occurrence, variability in renal histopathology, and heterogeneity in clinical course present challenges in clinical studies and have resulted in a relative paucity of data and uncertainty with regard to the optimal management of HBV-related glomerular diseases. The advent of nucleos(t)ide analogue medications that effectively suppress HBV replication has markedly altered the clinical outcomes of kidney transplant recipients with HBV infection, but the emergence of drug resistance is an escalating problem. This article reviews the recent knowledge of the pathogenesis and treatment of HBV-related membranous nephropathy, and discusses the management of hepatitis B in kidney transplant recipients, which is continuously evolving. © 2010 The Author(s).en_HK
dc.languageengen_HK
dc.publisherSpringer Healthcare. The Journal's web site is located at http://www.springerlink.com/content/1540-3416/en_HK
dc.relation.ispartofCurrent Hepatitis Reportsen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsThe original publication is available at www.springerlink.comen_HK
dc.subjectHepatitis Ben_HK
dc.subjectKidney transplantationen_HK
dc.titleHepatitis B and Renal Diseaseen_HK
dc.typeArticleen_HK
dc.identifier.emailChan, TM:dtmchan@hku.hken_HK
dc.identifier.authorityChan, TM=rp00394en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1007/s11901-010-0042-6en_HK
dc.identifier.pmid20461128-
dc.identifier.pmcidPMC2861764-
dc.identifier.scopuseid_2-s2.0-77955983326en_HK
dc.identifier.hkuros178492-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77955983326&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.issue2en_HK
dc.identifier.spage99en_HK
dc.identifier.epage105en_HK
dc.identifier.eissn1541-0706en_HK
dc.publisher.placeUnited Statesen_HK
dc.description.otherSpringer Open Choice, 01 Dec 2010-
dc.identifier.scopusauthoridChan, TM=7402687700en_HK
dc.identifier.citeulike7042908-

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