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Article: Arterial stiffness in the young: Assessment, determinants, and implications

TitleArterial stiffness in the young: Assessment, determinants, and implications
Authors
KeywordsArteriosclerosis
Children
Issue Date2010
PublisherKorean Society of Circulation. The Journal's web site is located at http://journal.circulation.or.kr/
Citation
Korean Circulation Journal, 2010, v. 40 n. 4, p. 153-162 How to Cite?
AbstractArterial stiffness describes the rigidity of the arterial wall. Its significance owes to its relationship with the pulsatile afterload presented to the left ventricle and its implications on ventricular-arterial coupling. In adults, the contention that arterial stiffness as a marker and risk factor for cardiovascular morbidity and mortality is gaining support. Noninvasive methods have increasingly been adopted in both the research and clinical arena to determine local, segmental, and systemic arterial stiffness in the young. With adoption of these noninvasive techniques for use in children and adolescents, the phenomenon and significance of arterial stiffening in the young is beginning to be unveiled. The list of childhood factors and conditions found to be associated with arterial stiffening has expanded rapidly over the last decade; these include traditional cardiovascular risk factors, prenatal growth restriction, vasculitides, vasculopathies associated with various syndromes, congenital heart disease, and several systemic diseases. The findings of arterial stiffening have functional implications on energetic efficiency, structure, and function of the left ventricle. Early identification of arterial dysfunction in childhood may provide a window for early intervention, although longitudinal studies are required to determine whether improvement of arterial function in normal and at-risk paediatric populations will be translated into clinical benefits. Copyright ©2010 The Korean Society of Cardiology.
Persistent Identifierhttp://hdl.handle.net/10722/123972
ISSN
2015 Impact Factor: 0.706
2015 SCImago Journal Rankings: 0.362
PubMed Central ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, YFen_HK
dc.date.accessioned2010-10-13T08:46:16Z-
dc.date.available2010-10-13T08:46:16Z-
dc.date.issued2010en_HK
dc.identifier.citationKorean Circulation Journal, 2010, v. 40 n. 4, p. 153-162en_HK
dc.identifier.issn1738-5520en_HK
dc.identifier.urihttp://hdl.handle.net/10722/123972-
dc.description.abstractArterial stiffness describes the rigidity of the arterial wall. Its significance owes to its relationship with the pulsatile afterload presented to the left ventricle and its implications on ventricular-arterial coupling. In adults, the contention that arterial stiffness as a marker and risk factor for cardiovascular morbidity and mortality is gaining support. Noninvasive methods have increasingly been adopted in both the research and clinical arena to determine local, segmental, and systemic arterial stiffness in the young. With adoption of these noninvasive techniques for use in children and adolescents, the phenomenon and significance of arterial stiffening in the young is beginning to be unveiled. The list of childhood factors and conditions found to be associated with arterial stiffening has expanded rapidly over the last decade; these include traditional cardiovascular risk factors, prenatal growth restriction, vasculitides, vasculopathies associated with various syndromes, congenital heart disease, and several systemic diseases. The findings of arterial stiffening have functional implications on energetic efficiency, structure, and function of the left ventricle. Early identification of arterial dysfunction in childhood may provide a window for early intervention, although longitudinal studies are required to determine whether improvement of arterial function in normal and at-risk paediatric populations will be translated into clinical benefits. Copyright ©2010 The Korean Society of Cardiology.en_HK
dc.languageeng-
dc.publisherKorean Society of Circulation. The Journal's web site is located at http://journal.circulation.or.kr/en_HK
dc.relation.ispartofKorean Circulation Journalen_HK
dc.subjectArteriosclerosisen_HK
dc.subjectChildrenen_HK
dc.titleArterial stiffness in the young: Assessment, determinants, and implicationsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1738-5520&volume=40&issue=4&spage=153&epage=162&date=2010&atitle=Arterial+stiffness+in+the+young:+assessment,+determinants,+and+implications-
dc.identifier.emailCheung, YF:xfcheung@hku.hken_HK
dc.identifier.authorityCheung, YF=rp00382en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.4070/kcj.2010.40.4.153en_HK
dc.identifier.pmid20421954-
dc.identifier.pmcidPMC2859331-
dc.identifier.scopuseid_2-s2.0-77952200654en_HK
dc.identifier.hkuros169948-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77952200654&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume40en_HK
dc.identifier.issue4en_HK
dc.identifier.spage153en_HK
dc.identifier.epage162en_HK
dc.publisher.placeKorea, Republic ofen_HK
dc.identifier.scopusauthoridCheung, YF=7202111067en_HK

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