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Professor Ngan, Hextan Yuen Sheung 顏婉嫦

Title:
Professor, Chair of Obstetrics and Gynaecology
Tsao Yin Kai Professor in Obstetrics & Gynaecology
Clinical Professor

Department:
Department of Obstetrics and Gynaecology

Faculty:
Li Ka Shing Faculty of Medicine

Principal Investigator
StatusProject CodeProject TitleAmountFunding Year
 
N/APrimary high dose cisplatinum combination chemotherapy in advanced ovarian cancer01987
 
HKU 271/92MStudy of the role of p53, a tumour suppressor gene and the role of human papilloma virus (HPV) 16 and 18 in the patho-genesis of cervical cancer in Hong Kong Chinese4920001992
 
N/AThe role of contact hysteroscope in staging of endometrial carcinoma01987
 
HKU 230/95MStudy of protooncogenes and search of new genetic alterations in cervical cancer in Hong Kong Chinese3100001995
 
N/AThe value of CA125 and TPA as a tumour marker in ovarian cancer01987
 
N/APilot study on incidence of human papillomavirus infection of the cervix among women attending Social Hygiene Clinic in Hong Kong01990
 
N/ACombination chemotherapy for platinum resistant ovarian cancer01984
 
N/AImmunomodulation of G.E. Yun Zhi (PSK) in gynaecologic cancer patients3000001997
 
N/AGene therapy in cervical cancer8000001997
 
N/AHigh dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer01994
 
N/AUrinary [beta]-core hCG in gyn. cancer01993
 
N/ASCC as a tumour marker for cervical cancer01987
 
N/AStudy of human papilloma virus and p53 in vulvar cancer in Hong Kong Chinese200001994
 
05050052Study of human papillomavirus status in Southern Chinese women with normal cervix, precancerous cervical lesions and cervical cancers8049542005
 
HKU 776411MFunctional characterization and clinical significance of DNp73-C35 in ovarian cancer9500002011
 
12111022Clinical significance and application of HPV-related microRNAs in cervical pre-maglinant lesions and cancer6666002012
 
HKU 775913MRoles of HPV-E6 protein and CD55(+) population in regulating radio-resistance in cervical cancer cells12557472013
 
17117014Functional characterization of CD71(+) population and the roles of HPV-E6 protein in cervical cancer6715522014
 
17121220Deciphering the Dichotomous Effects and Molecular Mechanisms of BCL2A1 in Regulating Ovarian Cancer Dissemination9962852020
Co-Investigator
StatusProject CodeProject TitleAmountFunding Year
 
UIM/367Using Genome-wide DNA Methylome Profiling to Analyze Cisplatin-resistance in Human Ovarian Cancers37253642018
 
C7018-14EMicro-PET for pre-clinical molecular imaging research in Hong Kong80014862014
 
N/ATumour Microenvironment - New concepts and molecular mechanisms6000002010
 
HKU 761413MDifferential roles of estrogen receptor subtypes and variants in ovarian cancer: implications for personalized hormonal treatment.7361282013
 
N/Ap21-activated kinase 4: a prognostic and therapeutic target for ovarian carcinoma?2961372007
 
13142951Combined Electroacupuncture and Auricular Acupuncture for Postoperative Pain after Abdominal Surgery for Gynecological Diseases: A Randomized Sham-controlled Trial7617072015
 
09201976Ferroptosis as potential target in ovarian cancer therapy14982482021
 
14150971An interactive computer-based intervention to adopt safer sex practice for female university students: a multicentred randomized controlled trial6382982016
 
HKU 7503/06MAkt and p21-activated kinase signaling pathways in gestational trophoblastic disease8445002006
 
PiH/155/19Using Genome-wide DNA Methylome Profiling to Analyze Cisplatin-resistance in Human Ovarian Cancers8029672019
 
HKU 7281/00MDifferential expression of genes in gestational trophoblastic diseases7314002000
 
06171706Monitoring treatment response in advanced ovarian cancer by PET-CT following neo-adjuvant chemotherapy13819162018
 
01121366Cellular functions and potential clinical application of miR-143 in cervical cancer9915682013
 
HKU 7309/04MStem cell related genes in gestational trophoblastic diseases9399682004
 
N/APsychosocial aspects of gynaecological cancers and their therapies01983
 
N/AAdjuvant chemotherapy for high risk cervical cancer patients01987
 
18191641Delineation of reactive oxygen species (ROS)-mediated signaling pathways involved in developing chemoresistance in ovarian cancer13651842020
 
HKU 784413MMicroRNA-135a transforms normal HPV infected cervical cells into cancer cells and cells with cancer stem cell-like properties8487122013
 
206208HPV detection - an adjunct to triage of atypical cervical cytology in screening for risk of cervical cancer7112002006
 
05162176Targeting Human papillomavirus (HPV) negative cervical cancer11993842017
 
HKU 761213MFunctional significance of TAK1-mediated NFkB signaling in omental metastasis of ovarian cancer10392392013
 
211258HPV detection as an adjunct for triage of atypical cervical cytology in screening for cervical cancer13489832011
 
N/AThe behaviour of partial mole01979
 
HKU 7251/98MIn situ analysis of tissue dynamics in gestational trophoblastic disease6190001998
 
N/AUrinary human hCG [beta]-core fragment level in gynaecological cancers, mole and gestational trophoblastic neoplasia01989
 
HKU 7441/03MThe role of p73 in radiation response in cervical cancer8910002003
 
19181142Clinical performance of Human Papillomavirus (HPV) genotyping versus PAX1/SOX1 methylation as a triage for high-risk HPV positive women in cervical cancer screening in Hong Kong9537652019
 
17119916Characterising and quantifying intratumour heterogeneity in cervical cancer with intravoxel incoherent motion diffusion-weighted MRI.5701152016
 
01030361A prospective randomized controlled trial: prevention of Lymphedema by Omentoplasty after pelvic lymphadenectomy1879592003
 
17108421Characterization of NUAK2 pathways and functions in ovarian cancer11352322021
 
13142271Functional characterization of the MAP30 protein from bitter melon (Momordica chrantia) in combating ovarian cancer oncogenesis and chemoresistance11971602015
 
N/AThe value of free [beta]-submit and [alpha]-submit in the prediction and management of postmolar trophoblastic disease01987
 
01121336p53 related proteins and gestational trophoblastic disease9983602013
 
N/APrimary VAC regimen for non-dysgerminomatous germ cell tumours of the ovary01976
 
N/AThe prognostic significance of serum tumour markers and p53 abnormal expression in carcinoma of endometrium200001994
 
Breastfeeding-HKUBaby-friendly Community Initiative Program in Hong Kong35000002018
 
07060562Integrated human papilloma virus analysis as adjunct for triage of atypical cervical cytology7989232007
 
HKU 763211MFBI-1 (Pokemon) in Gestational Trophoblastic Disease5600002011
 
N/AStudy on the natural killer activity in the ovarian vein in patients with ovarian carcinoma01987
 
06060642Cervical cancer screening by enhanced cervical cytology-application of novel markers7742512006
 
03143616Translating functional tumour volume and biology of peritoneal carcinomatosis to identify suitable candidate for cytoreductive surgery in ovarian carcinoma.7825922015
 
01120936Placental biology of Down Syndrome in relation to increased gene dosage9985442013
 
17115115The functional role of Hsa-miR-141 in metastatic progression of ovarian cancer13447142015
 
03143006p21 activated kinase 4 and ovarian cancer chemoresistance11796082015
 
PiH/154/19Using Genome-wide DNA Methylome Profiling to Analyze Cisplatin-resistance in Human Ovarian Cancers8008482019
 
N/APVB regimen for VAC resistant germ cell tumour01980
 
17118322The impact of CXCL10 derived from ovarian cancer cells on T cell antitumor immunity10205032022
 
HKU 397/94MA study on the expression of oncogene, tumour suppressor gene and growth factors in normal human placenta and gestational trophoblastic disease5290001994
 
HKU 760511MThe functional impact of AMP-activated protein kinase gamma-2 (AMPK-g2)subunit expression on AMPK activity and oncogenesis in ovarian cancer10200002011
 
81472721The mechanism and significance of ovarian cancer cells in modulating AMPK and TNFkB signaling cascade in omental metastasis9420002014
 
15161881The use of a new biomarker, HE4, in combination with simple ultrasound rules in the prediction of malignancy in a pelvic mass detected on ultrasound8183442017
 
17101414Role of pyruvate dehydrogenase kinase 1 (PDK1) in tumorigenesis and metastasis of ovarian cancer5672022014
 
N/ACytogenetic analysis of gestational trophoblastic disease by chromosome in situ hybridization200001994
 
N/ALymphocyte subpopulations and natural killer cell activity in patients with cervical carcinoma01987
 
N/AChemotherapy for recurrent cervical cancer01983
 
N/AAdjuvant chemotherapy for advanced cervical cancer01987