The functional role of Hsa-miR-141 in metastatic progression of ovarian cancer


Grant Data
Project Title
The functional role of Hsa-miR-141 in metastatic progression of ovarian cancer
Principal Investigator
Dr Chan, David Wai   (Principal investigator)
Co-Investigator(s)
Duration
36
Start Date
2015-11-01
Completion Date
2018-10-31
Amount
1344714
Conference Title
Presentation Title
Keywords
Anoikis, ovarian cancer, secretary miRNAs, tumor microenvironment, omental metastasis
Discipline
Cancer
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17115115
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To study the molecular mechanism of miR-141 in cell-to-cell communication. 3 To investigate the significance and mechanism of cancer-secreted miR-141 in remodeling fibroblast cells and promoting ovarian cancer metastatic colonization.