The Role of interleukin-17 in the pathogenesis of experimental Sjögren's syndrome
Grant Data
Project Title
The Role of interleukin-17 in the pathogenesis of experimental Sjögren's syndrome
Principal Investigator
Professor Lu, Liwei
(Principal Investigator (PI))
Duration
36
Start Date
2017-01-01
Amount
1158650
Conference Title
The Role of interleukin-17 in the pathogenesis of experimental Sjögren's syndrome
Presentation Title
Keywords
Autoimmunity, IL-17, Lymphocytes, Sjögren’s syndrome
Discipline
Allergy/Immunology
Panel
Biology and Medicine (M)
HKU Project Code
17149716
Grant Type
General Research Fund (GRF)
Funding Year
2016
Status
Completed
Objectives
1 To determine the role of IL-17 in modulating the function of salivary epithelial cells 2 To elucidate the function of IL-17 in regulating lymphocytic infiltration during ESS development 3 To investigate the therapeutic effect of targeting IL-17 on disease progression in ESS mice