Neurodevelopmental eflect of gene-environment interaction among early-onset schizophrenia patients: a combined genetic and neuroimaging approach


Grant Data
Project Title
Neurodevelopmental eflect of gene-environment interaction among early-onset schizophrenia patients: a combined genetic and neuroimaging approach
Principal Investigator
Professor Chen, Eric Yu Hai   (Principal investigator)
Co-Investigator(s)
Dr Chan Kit Wa   (Co-Investigator)
Dr Mwansisya Tumbwene   (Co-Investigator)
Dr Hui Christy Lai Ming   (Co-Investigator)
Dr Tao Haojuan   (Co-Investigator)
Dr Lee Ho Ming Edwin   (Co-Investigator)
Dr Zhou Li   (Co-Investigator)
Professor Liu Zhening   (Co-principal investigator)
Dr Lin Jingxia Jessie   (Co-Investigator)
Dr Liu Haihong   (Co-Investigator)
Dr Chang Wing Chung   (Co-Investigator)
Dr Huang Xiaojun   (Co-Investigator)
Dr Deng Mengjie   (Co-Investigator)
Duration
48
Start Date
2016-01-01
Completion Date
2019-12-31
Amount
1195955
Conference Title
Presentation Title
Keywords
Gene-environment interaction, early-onset schizophrenia, genetic, neuroimaging
Discipline
Neuroscience,Genomic Biology
Panel
Medicine
Sponsor
NSFC/RGC Joint Research Scheme
HKU Project Code
N_HKU732/15
Grant Type
NSFC/RGC Joint Research Scheme
Funding Year
2015/2016
Status
On-going
Objectives
2. To investigate the relationship between dysbindin-1 isoforms and abnormal brain structures and disconnectivity in Chinese early-onset schizophrenia patients. 3. To examine the relationship between genetic expression of dysbindin-1 isoforms and childhood trauma in the Chinese early-onset schizophrenia patients and their healthy siblings.