The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors


Grant Data
Project Title
The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors
Principal Investigator
Dr Tso, Wan Yee Winnie   (Principal investigator)
Co-Investigator(s)
Dr Hui Sai Kam   (Co-Investigator)
Professor Khong Pek Lan   (Co-Investigator)
Professor Chan Godfrey Chi Fung   (Co-Investigator)
Dr Fong Daniel Yee Tak   (Co-Investigator)
Professor Lee Tatia Mei Chun   (Co-Investigator)
Duration
36
Start Date
2016-01-01
Completion Date
2018-12-31
Amount
630327
Conference Title
Presentation Title
Keywords
Intracranial germinoma, Cognitive outcome, Functional outcome, Diffusion kurtosis
Discipline
Paediatrics
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17118815
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To investigate the association between MR-DKI metrics, neurocognitive and functional outcomes in childhood intracranial germinoma survivors. 3 To compare the degree of white and gray matter loss, neurocognitive and functional outcomes in intracranial germinoma affecting different regions of the brain e.g. pineal vs. suprasellar vs. basal ganglia.