The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors
Grant Data
Project Title
The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors
Principal Investigator
Dr Tso, Wan Yee Winnie
(Principal Investigator (PI))
Co-Investigator(s)
Professor Lee Tatia Mei Chun
(Co-Investigator)
Dr Hui Sai Kam
(Co-Investigator)
Professor Khong Pek Lan
(Co-Investigator)
Professor Chan Godfrey Chi Fung
(Co-Investigator)
Dr Fong Daniel Yee Tak
(Co-Investigator)
Duration
36
Start Date
2016-01-01
Amount
630327
Conference Title
The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors
Presentation Title
Keywords
Cognitive outcome, Diffusion kurtosis, Functional outcome, Intracranial germinoma
Discipline
Paediatrics
Panel
Biology and Medicine (M)
HKU Project Code
17118815
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 To determine the degree of cognitive and functional impairment in intracranial germinoma survivors. 2 To investigate the association between MR-DKI metrics, neurocognitive and functional outcomes in childhood intracranial germinoma survivors. 3 To compare the degree of white and gray matter loss, neurocognitive and functional outcomes in intracranial germinoma affecting different regions of the brain e.g. pineal vs. suprasellar vs. basal ganglia.