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Conference Paper: MRI detection of peritoneal adhesion with dialysate enhancement

TitleMRI detection of peritoneal adhesion with dialysate enhancement
Authors
Issue Date2008
PublisherInternational Society of Magnetic Resonance in Medicine
Citation
International Society of Magnetic Resonance in Medicine (ISMRM) 16th Scientific Meeting and Exhibition, Toronto, Canada, 3-9 May 2008, p. 2691 How to Cite?
AbstractThis study investigated the use of clinical peritoneal dialysis fluid (dialysate) as a peritoneal contrast agent to visualize peritoneal adhesions in rats at 7 Tesla. Intraperitoneal injection of dialysate (~0.1 mL/g) allowed the MR detection of peritoneal adhesions that were surgically induced in all rats studied (N = 6). MR measurements of adhesion surface areas correlated well with the postmortem estimations (R = 0.99). T1 and T2 values of undiluted dialysate were found to be 3017.5¡Ó35.3 ms and 108.4¡Ó2.0 ms, respectively. These findings demonstrated dialysate-enhanced MRI as a potentially valuable technique in clinical detection and evaluation of post-surgical peritoneal adhesion and to monitor therapeutic interventions (i.e., against peritoneal adhesion) in future preclinical research.
Persistent Identifierhttp://hdl.handle.net/10722/99807

 

DC FieldValueLanguage
dc.contributor.authorCheung, JSen_HK
dc.contributor.authorGuo, Hen_HK
dc.contributor.authorLeung, JCen_HK
dc.contributor.authorLai, KNen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-09-25T18:44:57Z-
dc.date.available2010-09-25T18:44:57Z-
dc.date.issued2008en_HK
dc.identifier.citationInternational Society of Magnetic Resonance in Medicine (ISMRM) 16th Scientific Meeting and Exhibition, Toronto, Canada, 3-9 May 2008, p. 2691-
dc.identifier.urihttp://hdl.handle.net/10722/99807-
dc.description.abstractThis study investigated the use of clinical peritoneal dialysis fluid (dialysate) as a peritoneal contrast agent to visualize peritoneal adhesions in rats at 7 Tesla. Intraperitoneal injection of dialysate (~0.1 mL/g) allowed the MR detection of peritoneal adhesions that were surgically induced in all rats studied (N = 6). MR measurements of adhesion surface areas correlated well with the postmortem estimations (R = 0.99). T1 and T2 values of undiluted dialysate were found to be 3017.5¡Ó35.3 ms and 108.4¡Ó2.0 ms, respectively. These findings demonstrated dialysate-enhanced MRI as a potentially valuable technique in clinical detection and evaluation of post-surgical peritoneal adhesion and to monitor therapeutic interventions (i.e., against peritoneal adhesion) in future preclinical research.-
dc.languageengen_HK
dc.publisherInternational Society of Magnetic Resonance in Medicine-
dc.relation.ispartof2008 Proceedings of International Society of Magnetic Resonance in Medicineen_HK
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleMRI detection of peritoneal adhesion with dialysate enhancementen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros141572en_HK

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