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Conference Paper: Evaluation of glaucomatous optic nerve using in vivo manganese-enhanced MRI

TitleEvaluation of glaucomatous optic nerve using in vivo manganese-enhanced MRI
Authors
Issue Date2007
PublisherInternational Society for Magnetic Resonance in Medicine
Citation
Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany, 19-25 May 2007. In 2007 Scientific Meeting Proceedings, 2007, p. 481 Abstract no. 2459 How to Cite?
AbstractTo our knowledge, three dimensional, non-invasive in vivo imaging has not previously been possible for the detection of structural or functional neuronal damage of the rat visual pathway induced by glaucoma due to the small size of rat eyes. In this study, manganese-enhanced magnetic resonance imaging (MEMRI) was applied to evaluate dynamically the Mn2+ enhancements along the visual pathway following an induction of ocular hypertension in rat models of chronic glaucoma. Results showed that MEMRI can detect abnormalities in the glaucomatous optic nerves non-invasively, and may help understand the disease mechanisms and monitor the effect of drug interventions to glaucoma models.
Persistent Identifierhttp://hdl.handle.net/10722/99101

 

DC FieldValueLanguage
dc.contributor.authorChan, KCen_HK
dc.contributor.authorFu, SQen_HK
dc.contributor.authorHui, ESen_HK
dc.contributor.authorLi, RSen_HK
dc.contributor.authorCheung, MMen_HK
dc.contributor.authorLi, DTen_HK
dc.contributor.authorSo, KFen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-09-25T18:15:53Z-
dc.date.available2010-09-25T18:15:53Z-
dc.date.issued2007en_HK
dc.identifier.citationJoint Annual Meeting ISMRM-ESMRMB, Berlin, Germany, 19-25 May 2007. In 2007 Scientific Meeting Proceedings, 2007, p. 481 Abstract no. 2459en_HK
dc.identifier.urihttp://hdl.handle.net/10722/99101-
dc.description.abstractTo our knowledge, three dimensional, non-invasive in vivo imaging has not previously been possible for the detection of structural or functional neuronal damage of the rat visual pathway induced by glaucoma due to the small size of rat eyes. In this study, manganese-enhanced magnetic resonance imaging (MEMRI) was applied to evaluate dynamically the Mn2+ enhancements along the visual pathway following an induction of ocular hypertension in rat models of chronic glaucoma. Results showed that MEMRI can detect abnormalities in the glaucomatous optic nerves non-invasively, and may help understand the disease mechanisms and monitor the effect of drug interventions to glaucoma models.-
dc.languageengen_HK
dc.publisherInternational Society for Magnetic Resonance in Medicine-
dc.relation.ispartofJoint Annual Meeting ISMRM-ESMRMBen_HK
dc.titleEvaluation of glaucomatous optic nerve using in vivo manganese-enhanced MRIen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.identifier.hkuros134569en_HK

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