File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Evaluation of the visual system in rat models of chronic glaucoma using manganese-enhanced magnetic resonance imaging

TitleEvaluation of the visual system in rat models of chronic glaucoma using manganese-enhanced magnetic resonance imaging
Authors
Issue Date2007
PublisherIEEE. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269
Citation
The 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBS 2007), Lyon, France, 22-26 August 2007. In IEEE Engineering in Medicine and Biology Society Conference Proceedings, 2007, p. 67-70 How to Cite?
AbstractThis study aims to employ in vivo manganese- enhanced MRI (MEMRI) to evaluate dynamically the Mn2+ enhancements along the visual pathway following an induction of ocular hypertension in a rat model of chronic glaucoma. Results showed an accumulation of Mn2+ ions in the vitreous humor of the glaucomatous eye, with no statistical changes in the total retinal thickness but a possible occlusion of the ions at the optic nerve head. Meanwhile, there was a reduction in Mn2+ transport in the glaucomatous optic nerve in the later stage of our model. Fewer enhancements in the visual cortex projected from the glaucomatous eye were also detectable. These may help understand the disease mechanisms, monitor the effect of drug interventions to glaucoma models, and complement the conventional techniques in examining the visual components.
Persistent Identifierhttp://hdl.handle.net/10722/98947
ISBN
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorChan, KCen_HK
dc.contributor.authorFu, SQen_HK
dc.contributor.authorSo, KFen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-09-25T18:09:14Z-
dc.date.available2010-09-25T18:09:14Z-
dc.date.issued2007en_HK
dc.identifier.citationThe 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBS 2007), Lyon, France, 22-26 August 2007. In IEEE Engineering in Medicine and Biology Society Conference Proceedings, 2007, p. 67-70-
dc.identifier.isbn978-1-4244-0787-3-
dc.identifier.issn1557-170X-
dc.identifier.urihttp://hdl.handle.net/10722/98947-
dc.description.abstractThis study aims to employ in vivo manganese- enhanced MRI (MEMRI) to evaluate dynamically the Mn2+ enhancements along the visual pathway following an induction of ocular hypertension in a rat model of chronic glaucoma. Results showed an accumulation of Mn2+ ions in the vitreous humor of the glaucomatous eye, with no statistical changes in the total retinal thickness but a possible occlusion of the ions at the optic nerve head. Meanwhile, there was a reduction in Mn2+ transport in the glaucomatous optic nerve in the later stage of our model. Fewer enhancements in the visual cortex projected from the glaucomatous eye were also detectable. These may help understand the disease mechanisms, monitor the effect of drug interventions to glaucoma models, and complement the conventional techniques in examining the visual components.-
dc.languageengen_HK
dc.publisherIEEE. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/conhome.jsp?punumber=1000269-
dc.relation.ispartofIEEE Engineering in Medicine and Biology Society Conference Proceedingsen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleEvaluation of the visual system in rat models of chronic glaucoma using manganese-enhanced magnetic resonance imagingen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailSo, KF: hrmaskf@hkucc.hku.hken_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authoritySo, KF=rp00329en_HK
dc.identifier.authorityWu, EX=rp00193-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1109/IEMBS.2007.4352224-
dc.identifier.pmid18001890-
dc.identifier.scopuseid_2-s2.0-57649183627-
dc.identifier.hkuros141516en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-57649183627&selection=ref&src=s&origin=recordpage-
dc.identifier.spage67-
dc.identifier.epage70-
dc.publisher.placeUnited States-
dc.identifier.scopusauthoridChan, KC=34968940300-
dc.identifier.scopusauthoridFu, QL=23388762000-
dc.identifier.scopusauthoridSo, KF=34668391300-
dc.identifier.scopusauthoridWu, EX=7202128034-
dc.customcontrol.immutablesml 160114 - merged-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats