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Conference Paper: Detection of transient changes in photothrombotic cortical injury by manganese-enhanced magnetic resonance imaging

TitleDetection of transient changes in photothrombotic cortical injury by manganese-enhanced magnetic resonance imaging
Authors
Issue Date2008
Citation
The 16th Annual Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2008), Toronto, ON., Canada, 3-9 May 2008. In Conference Proceedings, 2008, no. 532 How to Cite?
AbstractThis study aims to employ in vivo manganese-enhanced MRI to detect transient changes in adult rat model of photothrombotic cortical injury in different brain regions. Results showed a close pattern of MEMRI signal hyperintensity throughout different brain regions in comparison to the distribution of MnSOD and GS immunoreactivities along the time course, whereby conventional MRI could hardly detect such. It is suggested that exogenous Mn2+ injection may provide enhanced MEMRI detection of oxidative stress and gliosis early in the rat model of photothrombotic cortical injury.
DescriptionSession - Manganese in the Brain: Methods to Applications: no. 532
Persistent Identifierhttp://hdl.handle.net/10722/98936

 

DC FieldValueLanguage
dc.contributor.authorChan, KCen_HK
dc.contributor.authorSu, HXen_HK
dc.contributor.authorCai, KXen_HK
dc.contributor.authorChiu, CTen_HK
dc.contributor.authorCheng, MMen_HK
dc.contributor.authorWu, WTen_HK
dc.contributor.authorWu, EXen_HK
dc.date.accessioned2010-09-25T18:08:44Z-
dc.date.available2010-09-25T18:08:44Z-
dc.date.issued2008en_HK
dc.identifier.citationThe 16th Annual Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2008), Toronto, ON., Canada, 3-9 May 2008. In Conference Proceedings, 2008, no. 532en_HK
dc.identifier.urihttp://hdl.handle.net/10722/98936-
dc.descriptionSession - Manganese in the Brain: Methods to Applications: no. 532-
dc.description.abstractThis study aims to employ in vivo manganese-enhanced MRI to detect transient changes in adult rat model of photothrombotic cortical injury in different brain regions. Results showed a close pattern of MEMRI signal hyperintensity throughout different brain regions in comparison to the distribution of MnSOD and GS immunoreactivities along the time course, whereby conventional MRI could hardly detect such. It is suggested that exogenous Mn2+ injection may provide enhanced MEMRI detection of oxidative stress and gliosis early in the rat model of photothrombotic cortical injury.-
dc.languageengen_HK
dc.relation.ispartofISMRM 16th Annual Scientific Meeting & Exhibition Proceedingsen_HK
dc.titleDetection of transient changes in photothrombotic cortical injury by manganese-enhanced magnetic resonance imagingen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.identifier.hkuros141566en_HK

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