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Conference Paper: MRI and image quantitation for assessment of the growth effects of anabolic steroid precursors in a guinea pig model

TitleMRI and image quantitation for assessment of the growth effects of anabolic steroid precursors in a guinea pig model
Authors
Issue Date2006
PublisherThe International Society for Magnetic Resonance in Medicine (ISMRM)
Citation
The International Society for Magnetic Resonance in Medicine 14th Scientific Meeting & Exhibition (ISMRM2006). Seattle, WA, 6-12 May 2006 How to Cite?
AbstractMRI and image quantitation play an expanding role in modern drug research. With effective image segmentation and analysis methods, in vivo and longitudinal tissue growth can be assessed. The effects of the nandrolone and testosterone steroids on muscle growth have been investigated previously, in which MRI acquisition and analysis protocol were established, and excellent correlations were found between MRI measurement and dissection analyzes. In this study, the MRI protocol was used to evaluate the anabolic potential of 4 steroid precursors. The effects on muscle growth in castrated guinea pigs, in comparison with that of respective positive control steroids were determined.
Persistent Identifierhttp://hdl.handle.net/10722/98717

 

DC FieldValueLanguage
dc.contributor.authorTang, Hen_HK
dc.contributor.authorWu, EXen_HK
dc.contributor.authorVasseli, JRen_HK
dc.date.accessioned2010-09-25T17:59:21Z-
dc.date.available2010-09-25T17:59:21Z-
dc.date.issued2006en_HK
dc.identifier.citationThe International Society for Magnetic Resonance in Medicine 14th Scientific Meeting & Exhibition (ISMRM2006). Seattle, WA, 6-12 May 2006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/98717-
dc.description.abstractMRI and image quantitation play an expanding role in modern drug research. With effective image segmentation and analysis methods, in vivo and longitudinal tissue growth can be assessed. The effects of the nandrolone and testosterone steroids on muscle growth have been investigated previously, in which MRI acquisition and analysis protocol were established, and excellent correlations were found between MRI measurement and dissection analyzes. In this study, the MRI protocol was used to evaluate the anabolic potential of 4 steroid precursors. The effects on muscle growth in castrated guinea pigs, in comparison with that of respective positive control steroids were determined.-
dc.languageengen_HK
dc.publisherThe International Society for Magnetic Resonance in Medicine (ISMRM)-
dc.relation.ispartofThe International Society for Magnetic Resonance in Medicine Scientific Meeting & Exhibition (ISMRM)en_HK
dc.titleMRI and image quantitation for assessment of the growth effects of anabolic steroid precursors in a guinea pig modelen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWu, EX: ewu@eee.hku.hken_HK
dc.identifier.authorityWu, EX=rp00193en_HK
dc.identifier.hkuros119816en_HK

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