Gradient reversal technique revisited for simultaneous water and fat imaging at high field

Abstract

Qualitative and quantitative MR imaging of water and fat is of great importance in obesity and diabetic research, osteoarthritis cartilage visualization, body composition measurement, and drug evaluation studies. In this study, we revisited the gradient reversal technique, along with a chemical-shift-specific sliceselection (C4S) method. Simultaneous water and fat imaging approach was implemented at 11.7T. Using this technique, high quality water and fat images at the identical slice locations with in-plane chemical-shift correction were acquired in a single acquisition without increase in acquisition time. Applications in in vivo quantitative tissue lipid imaging were demonstrated.