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Article: Oxidative dissolution of silver nanoparticles by biologically relevant oxidants: A kinetic and mechanistic study

TitleOxidative dissolution of silver nanoparticles by biologically relevant oxidants: A kinetic and mechanistic study
Authors
KeywordsAgNPs. Nanostructures
Kinetics
Nanoparticles
Oxidation
Silver
Issue Date2010
PublisherWiley - V C H Verlag GmbH & Co. KGaA. The Journal's web site is located at http://www.wiley-vch.de/publish/en/journals/alphabeticIndex/2451
Citation
Chemistry - An Asian Journal, 2010, v. 5 n. 2, p. 285-293 How to Cite?
AbstractThe oxidative dissolution of silver nanoparticles (AgNPs) plays an important role in the synthesis of welldefined nanostructured materials, and may be responsible for their activities in biological systems. In this study, we use stopped-flow spectrophotometry to investigate the kinetics and mechanism of the oxidative dissolution of AgNPs by H 2O 2 in quasi-physiological conditions. Our results show that the reaction is first order with respect to both [Ag 0] and [H 2O 2], and parallel pathways that involve the oxidation of H 2O 2 and HO 2 - are proposed. The order of the reaction is independent of the size of the AgNPs (≈5-20 nm). The rate of dissolution increases with increasing pH from 6.0 to 8.5. At 298 K and I=0.1m, the value of k b is five orders of magnitude higher than that of k a (where k a and k b are the rate constants for the oxidative dissolution of AgNPs by H 2O 2 and HO 2 -, respectively). In addition, the effects of surface coating and the presence of halide ions on the dissolution rates are investigated. A possible mechanism for the oxidative dissolution of AgNPs by H 2O 2 is proposed. We further demonstrate that the toxicities of AgNPs in both bacteria and mammalian cells are enhanced in the presence of H 2O 2, thereby highlighting the biological relevance of investigating the oxidative dissolution of AgNPs. © 2010 Wiley-VCH Verlag GmbH&Co. KGaA, Weinheim.
Persistent Identifierhttp://hdl.handle.net/10722/97360
ISSN
2015 Impact Factor: 4.592
2015 SCImago Journal Rankings: 1.833
ISI Accession Number ID
Funding AgencyGrant Number
Hong Kong Research Grants CouncilHKU 7029/09
AoE/P 10/01
Funding Information:

This work was supported by the Hong Kong Research Grants Council (HKU 7029/09) and the Area of Excellence (AoE/P 10/01) established under the University Grants Committee of the Hong Kong SAR. We are grateful to Professor T.-C. Lau of City Univeisity of Hong, Kong for access to the equipment for kinetic measurements and Dr. Rory Wait for his help in editing this Manuscript. We thank one reviewer for making suggestions on the oxidative dissolution rates.

References

 

DC FieldValueLanguage
dc.contributor.authorHo, CMen_HK
dc.contributor.authorYau, SKWen_HK
dc.contributor.authorLok, CNen_HK
dc.contributor.authorSo, MHen_HK
dc.contributor.authorChe, CMen_HK
dc.date.accessioned2010-09-25T17:06:06Z-
dc.date.available2010-09-25T17:06:06Z-
dc.date.issued2010en_HK
dc.identifier.citationChemistry - An Asian Journal, 2010, v. 5 n. 2, p. 285-293en_HK
dc.identifier.issn1861-4728en_HK
dc.identifier.urihttp://hdl.handle.net/10722/97360-
dc.description.abstractThe oxidative dissolution of silver nanoparticles (AgNPs) plays an important role in the synthesis of welldefined nanostructured materials, and may be responsible for their activities in biological systems. In this study, we use stopped-flow spectrophotometry to investigate the kinetics and mechanism of the oxidative dissolution of AgNPs by H 2O 2 in quasi-physiological conditions. Our results show that the reaction is first order with respect to both [Ag 0] and [H 2O 2], and parallel pathways that involve the oxidation of H 2O 2 and HO 2 - are proposed. The order of the reaction is independent of the size of the AgNPs (≈5-20 nm). The rate of dissolution increases with increasing pH from 6.0 to 8.5. At 298 K and I=0.1m, the value of k b is five orders of magnitude higher than that of k a (where k a and k b are the rate constants for the oxidative dissolution of AgNPs by H 2O 2 and HO 2 -, respectively). In addition, the effects of surface coating and the presence of halide ions on the dissolution rates are investigated. A possible mechanism for the oxidative dissolution of AgNPs by H 2O 2 is proposed. We further demonstrate that the toxicities of AgNPs in both bacteria and mammalian cells are enhanced in the presence of H 2O 2, thereby highlighting the biological relevance of investigating the oxidative dissolution of AgNPs. © 2010 Wiley-VCH Verlag GmbH&Co. KGaA, Weinheim.en_HK
dc.languageengen_HK
dc.publisherWiley - V C H Verlag GmbH & Co. KGaA. The Journal's web site is located at http://www.wiley-vch.de/publish/en/journals/alphabeticIndex/2451en_HK
dc.relation.ispartofChemistry - An Asian Journalen_HK
dc.subjectAgNPs. Nanostructuresen_HK
dc.subjectKineticsen_HK
dc.subjectNanoparticlesen_HK
dc.subjectOxidationen_HK
dc.subjectSilveren_HK
dc.subject.meshHydrogen Peroxide - chemistry-
dc.subject.meshHydrogen-Ion Concentration-
dc.subject.meshKinetics-
dc.subject.meshMetal Nanoparticles - chemistry-
dc.subject.meshSilver - chemistry-
dc.titleOxidative dissolution of silver nanoparticles by biologically relevant oxidants: A kinetic and mechanistic studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1861-4728&volume=5&issue=2&spage=285&epage=293&date=2010&atitle=Oxidative+Dissolution+of+Silver+Nanoparticles+by+Biologically+Relevant+Oxidants.+A+kinetic+and+Mechanistic+Study-
dc.identifier.emailHo, CM: rickyho@hkucc.hku.hken_HK
dc.identifier.emailLok, CN: cnlok@hku.hken_HK
dc.identifier.emailChe, CM: cmche@hku.hken_HK
dc.identifier.authorityHo, CM=rp00705en_HK
dc.identifier.authorityLok, CN=rp00752en_HK
dc.identifier.authorityChe, CM=rp00670en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/asia.200900387en_HK
dc.identifier.pmid20063340-
dc.identifier.scopuseid_2-s2.0-76149133133en_HK
dc.identifier.hkuros168964en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-76149133133&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue2en_HK
dc.identifier.spage285en_HK
dc.identifier.epage293en_HK
dc.identifier.isiWOS:000274539100011-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridHo, CM=12807243800en_HK
dc.identifier.scopusauthoridYau, SKW=26647235100en_HK
dc.identifier.scopusauthoridLok, CN=7006410829en_HK
dc.identifier.scopusauthoridSo, MH=9275915300en_HK
dc.identifier.scopusauthoridChe, CM=7102442791en_HK

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