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Conference Paper: Expression of nicotinamide adenine dinucleotide phosphate-diaphorase in retinal ganglion cell layer of postnatal golden hamster depends on light stimulation

TitleExpression of nicotinamide adenine dinucleotide phosphate-diaphorase in retinal ganglion cell layer of postnatal golden hamster depends on light stimulation
Authors
Issue Date2004
PublisherThe Federation Of European Neuroscience Societies (FENS)
Citation
The 4th Forum of European Neurosicence, Lisbon, Portugal, 10-14 July 2004. In FENS Abstracts, 2004, v. 2, Abstract no. A194.8 How to Cite?
AbstractNADPH-d positive neurons in the retina of golden hamsters have been identified to be a subset of amacrine cells. Previous work has suggested that NADPH-d expressing amacrine cells in postnatal hamsters might be involved in the processing of visual function. The present study using histochemistry focuses on the changes of the expression of NADPH-d in the retina of postnatal hamsters reared in deprived normal light conditions. Prior to eye opening, P12 hamster pups were subjected to either bilateral eyelid suture or dark rearing. On P28 a subgroup of light deprived hamsters was returned to normal light conditions and the expression of NADPH-d activities in the retina was assessed. In hamsters reared in the normal 12:12 light-dark cycle condition, the number of NADPH-d amacrine cells in GCL increased gradually right after eye opening to reach the adult level. In contrast, hamsters subjected to both bilateral eyelid suture and dark rearing, the number of NADPH-d amacrine cells in GCL was maintained at a low level but up-regulated when returned to normal light-dark condition. This study demonstrates that the expression of NADPH-d in the retina of postnatal hamsters depends on the light stimulation implying that NADPH-d amacrine cells might play a role in processing of visual function.
Persistent Identifierhttp://hdl.handle.net/10722/95435

 

DC FieldValueLanguage
dc.contributor.authorChen, Ben_HK
dc.contributor.authorTay, DKCen_HK
dc.contributor.authorYu, EHen_HK
dc.contributor.authorSo, KFen_HK
dc.date.accessioned2010-09-25T16:02:11Z-
dc.date.available2010-09-25T16:02:11Z-
dc.date.issued2004en_HK
dc.identifier.citationThe 4th Forum of European Neurosicence, Lisbon, Portugal, 10-14 July 2004. In FENS Abstracts, 2004, v. 2, Abstract no. A194.8en_HK
dc.identifier.urihttp://hdl.handle.net/10722/95435-
dc.description.abstractNADPH-d positive neurons in the retina of golden hamsters have been identified to be a subset of amacrine cells. Previous work has suggested that NADPH-d expressing amacrine cells in postnatal hamsters might be involved in the processing of visual function. The present study using histochemistry focuses on the changes of the expression of NADPH-d in the retina of postnatal hamsters reared in deprived normal light conditions. Prior to eye opening, P12 hamster pups were subjected to either bilateral eyelid suture or dark rearing. On P28 a subgroup of light deprived hamsters was returned to normal light conditions and the expression of NADPH-d activities in the retina was assessed. In hamsters reared in the normal 12:12 light-dark cycle condition, the number of NADPH-d amacrine cells in GCL increased gradually right after eye opening to reach the adult level. In contrast, hamsters subjected to both bilateral eyelid suture and dark rearing, the number of NADPH-d amacrine cells in GCL was maintained at a low level but up-regulated when returned to normal light-dark condition. This study demonstrates that the expression of NADPH-d in the retina of postnatal hamsters depends on the light stimulation implying that NADPH-d amacrine cells might play a role in processing of visual function.-
dc.languageengen_HK
dc.publisherThe Federation Of European Neuroscience Societies (FENS)-
dc.relation.ispartofFENS Abstractsen_HK
dc.titleExpression of nicotinamide adenine dinucleotide phosphate-diaphorase in retinal ganglion cell layer of postnatal golden hamster depends on light stimulationen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailTay, DKC: dkctay@hkucc.hku.hken_HK
dc.identifier.emailSo, KF: hrmaskf@hkucc.hku.hken_HK
dc.identifier.authorityTay, DKC=rp00336en_HK
dc.identifier.authoritySo, KF=rp00329en_HK
dc.identifier.hkuros108071en_HK
dc.identifier.volume2en_HK

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