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Conference Paper: The Effect of Gusuibu on Bone Remodelling

TitleThe Effect of Gusuibu on Bone Remodelling
Authors
Issue Date2006
PublisherOxford University Press
Citation
The 81st Congress of European Orthodontic Society, Amsterdam, The Netherlands, 3–7 June 2005. In The European Journal of Orthodontics, 2006, v. 28 n. 2, p. e145 Abstract no.314 How to Cite?
AbstractAIM: Traditional Chinese medicines have been used in the Chinese population for the treatment of bone disease and to promote bone healing for several thousand years. Pan et al. (1992) examined the local effect of a Chinese herb, Gusuibu, on increasing the rate of orthodontic tooth movement in guinea pigs and rabbits. However, no information is known about the systemic effect of Gusuibu on bone. The aim of this investigation was to assess the systemic effect of Gusuibu consumption on bone histomorphology. MATERIALS AND METHOD: Twenty-eight-week-old male BALB/c mice were divided into two groups. In the control group, 10 mice were fed daily with distilled water, while in the Gusuibu group, 10 mice were fed daily with distilled water mixed with Gusuibu extract. The mice were kept for five weeks and were then killed. Using micro-computed tomography, 20 micro-tomographic slices with an increment of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. RESULTS: Consumption of Gusuibu extract increased the bone volume/tissue volume ratio by 6.45 per cent. Trabecular bone increased by 10 per cent, implying that the bone density was increased. CONCLUSION: Gusuibu extract taken orally increases bone density and triggers bone remodelling.
Persistent Identifierhttp://hdl.handle.net/10722/94847
ISSN
2015 Impact Factor: 1.44
2015 SCImago Journal Rankings: 1.090

 

DC FieldValueLanguage
dc.contributor.authorWong, RWKen_HK
dc.date.accessioned2010-09-25T15:43:43Z-
dc.date.available2010-09-25T15:43:43Z-
dc.date.issued2006en_HK
dc.identifier.citationThe 81st Congress of European Orthodontic Society, Amsterdam, The Netherlands, 3–7 June 2005. In The European Journal of Orthodontics, 2006, v. 28 n. 2, p. e145 Abstract no.314-
dc.identifier.issn0141-5387-
dc.identifier.urihttp://hdl.handle.net/10722/94847-
dc.description.abstractAIM: Traditional Chinese medicines have been used in the Chinese population for the treatment of bone disease and to promote bone healing for several thousand years. Pan et al. (1992) examined the local effect of a Chinese herb, Gusuibu, on increasing the rate of orthodontic tooth movement in guinea pigs and rabbits. However, no information is known about the systemic effect of Gusuibu on bone. The aim of this investigation was to assess the systemic effect of Gusuibu consumption on bone histomorphology. MATERIALS AND METHOD: Twenty-eight-week-old male BALB/c mice were divided into two groups. In the control group, 10 mice were fed daily with distilled water, while in the Gusuibu group, 10 mice were fed daily with distilled water mixed with Gusuibu extract. The mice were kept for five weeks and were then killed. Using micro-computed tomography, 20 micro-tomographic slices with an increment of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. RESULTS: Consumption of Gusuibu extract increased the bone volume/tissue volume ratio by 6.45 per cent. Trabecular bone increased by 10 per cent, implying that the bone density was increased. CONCLUSION: Gusuibu extract taken orally increases bone density and triggers bone remodelling.-
dc.languageengen_HK
dc.publisherOxford University Press-
dc.relation.ispartofThe European Journal of Orthodonticsen_HK
dc.titleThe Effect of Gusuibu on Bone Remodellingen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWong, RWK: fyoung@hkucc.hku.hken_HK
dc.identifier.emailRabie, ABM: rabie@hkusua.hku.hken_HK
dc.identifier.authorityWong, RWK=rp00038en_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/ejo/cjl019-
dc.identifier.hkuros100266en_HK

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