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Conference Paper: Bone induction using puerarin

TitleBone induction using puerarin
Authors
Issue Date2007
PublisherOxford University Press
Citation
The 83rd Congress of the European Orthodontic Society, Berlin, Germany, 20-24 July 2007. In The European Journal of Orthodontics, 2007, v. 29 n. 5, p. e107-e108 Abstract no.250 How to Cite?
AbstractAIM: Puerarin is one of the major phytoestrogens isolated from Pueraria lobata, a Chinese medicine known as Gegen. The aim of this investigation was to compare the amount of new bone produced by puerarin in collagen matrix (carrier) to that produced by the collagen matrix alone. MATERIALS AND METHOD: Eighteen bone defects, 5 × 10 mm, were created in the parietal bone of nine New Zealand White rabbits. In the experimental group, six defects were grafted with puerarin solution mixed with collagen matrix. In the control groups, six defects were grafted with collagen matrix alone (active control) and six were left empty (passive control). The animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Serial sections were cut across each defect. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. RESULTS: A total of 554 per cent more new bone was present in defects grafted with puerarin in collagen matrix than those grafted with collagen matrix alone. No bone was formed in the passive control group. CONCLUSIONS: Puerarin in collagen matrix has the effect of increasing new bone formation locally and can be used for bone grafting or for bone induction.
Persistent Identifierhttp://hdl.handle.net/10722/94189
ISSN
2015 Impact Factor: 1.44
2015 SCImago Journal Rankings: 1.090

 

DC FieldValueLanguage
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorRabie, ABMen_HK
dc.date.accessioned2010-09-25T15:24:01Z-
dc.date.available2010-09-25T15:24:01Z-
dc.date.issued2007en_HK
dc.identifier.citationThe 83rd Congress of the European Orthodontic Society, Berlin, Germany, 20-24 July 2007. In The European Journal of Orthodontics, 2007, v. 29 n. 5, p. e107-e108 Abstract no.250-
dc.identifier.issn0141-5387-
dc.identifier.urihttp://hdl.handle.net/10722/94189-
dc.description.abstractAIM: Puerarin is one of the major phytoestrogens isolated from Pueraria lobata, a Chinese medicine known as Gegen. The aim of this investigation was to compare the amount of new bone produced by puerarin in collagen matrix (carrier) to that produced by the collagen matrix alone. MATERIALS AND METHOD: Eighteen bone defects, 5 × 10 mm, were created in the parietal bone of nine New Zealand White rabbits. In the experimental group, six defects were grafted with puerarin solution mixed with collagen matrix. In the control groups, six defects were grafted with collagen matrix alone (active control) and six were left empty (passive control). The animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Serial sections were cut across each defect. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. RESULTS: A total of 554 per cent more new bone was present in defects grafted with puerarin in collagen matrix than those grafted with collagen matrix alone. No bone was formed in the passive control group. CONCLUSIONS: Puerarin in collagen matrix has the effect of increasing new bone formation locally and can be used for bone grafting or for bone induction.-
dc.languageengen_HK
dc.publisherOxford University Press-
dc.relation.ispartofThe European Journal of Orthodontics,en_HK
dc.titleBone induction using puerarinen_HK
dc.typeConference_Paperen_HK
dc.identifier.emailWong, RWK: fyoung@hkucc.hku.hken_HK
dc.identifier.emailRabie, ABM: rabie@hkusua.hku.hken_HK
dc.identifier.authorityWong, RWK=rp00038en_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/ejo/cjm091-
dc.identifier.hkuros128693en_HK

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