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Article: The expression analysis of Grb10 during mouse embryonic development

TitleThe expression analysis of Grb10 during mouse embryonic development
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2009
PublisherKexue Chubanshe
Citation
Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, 2009, v. 31 n. 7, p. 732-740 How to Cite?
AbstractGrb10 gene expression was analyzed in fetus and four organs during gestation process using the real-time RT-PCR and in situ hybridization. The real-time RT-PCR analysis result showed that the expression of Grb10 in whole embryos is throughout E8.5 to E19.5. The Grb10 gene expression level was gradually increased from E8.5 to E13.5, and then gradually reduced. The tissues specific expression levels were decreased in brain, heart, and lung from E12.5 to E19.5, but a peak expression was observed in liver at E18.5. Grb10 gene expression was also investigated at E13.5, E15.5, E16.5 and E18.5 sections by using in situ hybridization analysis. Strong signals of Grb10 were detected in brain, spine, kidney, and muscle tissues. These results suggest that Grb10 may play an important role during the development process in mouse.
Persistent Identifierhttp://hdl.handle.net/10722/92362
ISSN
2015 SCImago Journal Rankings: 0.177

 

DC FieldValueLanguage
dc.contributor.authorLiu, Qen_HK
dc.contributor.authorWang, Yen_HK
dc.contributor.authorChen, Yen_HK
dc.contributor.authorZhang, FWen_HK
dc.contributor.authorGu, TTen_HK
dc.contributor.authorQu, YPen_HK
dc.contributor.authorYue, Len_HK
dc.contributor.authorWu, Qen_HK
dc.date.accessioned2010-09-17T10:43:49Z-
dc.date.available2010-09-17T10:43:49Z-
dc.date.issued2009en_HK
dc.identifier.citationYi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, 2009, v. 31 n. 7, p. 732-740en_HK
dc.identifier.issn0253-9772en_HK
dc.identifier.urihttp://hdl.handle.net/10722/92362-
dc.description.abstractGrb10 gene expression was analyzed in fetus and four organs during gestation process using the real-time RT-PCR and in situ hybridization. The real-time RT-PCR analysis result showed that the expression of Grb10 in whole embryos is throughout E8.5 to E19.5. The Grb10 gene expression level was gradually increased from E8.5 to E13.5, and then gradually reduced. The tissues specific expression levels were decreased in brain, heart, and lung from E12.5 to E19.5, but a peak expression was observed in liver at E18.5. Grb10 gene expression was also investigated at E13.5, E15.5, E16.5 and E18.5 sections by using in situ hybridization analysis. Strong signals of Grb10 were detected in brain, spine, kidney, and muscle tissues. These results suggest that Grb10 may play an important role during the development process in mouse.en_HK
dc.languageengen_HK
dc.publisherKexue Chubansheen_HK
dc.relation.ispartofYi chuan = Hereditas / Zhongguo yi chuan xue hui bian jien_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.titleThe expression analysis of Grb10 during mouse embryonic developmenten_HK
dc.typeArticleen_HK
dc.identifier.emailChen, Y:ychenc@hkucc.hku.hken_HK
dc.identifier.authorityChen, Y=rp1318en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3724/SP.J.1005.2009.00732en_HK
dc.identifier.pmid19586879-
dc.identifier.scopuseid_2-s2.0-69449084565en_HK
dc.identifier.volume31en_HK
dc.identifier.issue7en_HK
dc.identifier.spage732en_HK
dc.identifier.epage740en_HK

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