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Article: A highly specific BODIPY-based fluorescent probe for the detection of hypochlorous acid

TitleA highly specific BODIPY-based fluorescent probe for the detection of hypochlorous acid
Authors
Issue Date2008
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html
Citation
Organic Letters, 2008, v. 10 n. 11, p. 2171-2174 How to Cite?
Abstract(Chemical Equation Presented) A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H2O2/Cl- system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems. © 2008 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/92303
ISSN
2015 Impact Factor: 6.732
2015 SCImago Journal Rankings: 3.187
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSun, ZNen_HK
dc.contributor.authorLiu, FQen_HK
dc.contributor.authorChen, Yen_HK
dc.contributor.authorTam, PKHen_HK
dc.contributor.authorYang, Den_HK
dc.date.accessioned2010-09-17T10:42:04Z-
dc.date.available2010-09-17T10:42:04Z-
dc.date.issued2008en_HK
dc.identifier.citationOrganic Letters, 2008, v. 10 n. 11, p. 2171-2174en_HK
dc.identifier.issn1523-7060en_HK
dc.identifier.urihttp://hdl.handle.net/10722/92303-
dc.description.abstract(Chemical Equation Presented) A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H2O2/Cl- system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems. © 2008 American Chemical Society.en_HK
dc.languageengen_HK
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.htmlen_HK
dc.relation.ispartofOrganic Lettersen_HK
dc.titleA highly specific BODIPY-based fluorescent probe for the detection of hypochlorous aciden_HK
dc.typeArticleen_HK
dc.identifier.emailSun, ZN: znsun@hku.hken_HK
dc.identifier.emailChen, Y: ychenc@hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hku.hken_HK
dc.identifier.emailYang, D: yangdan@hku.hken_HK
dc.identifier.authoritySun, ZN=rp00782en_HK
dc.identifier.authorityChen, Y=rp01318en_HK
dc.identifier.authorityTam, PKH=rp00060en_HK
dc.identifier.authorityYang, D=rp00825en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/ol800507men_HK
dc.identifier.pmid18447382-
dc.identifier.scopuseid_2-s2.0-52649151914en_HK
dc.identifier.hkuros143234-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-52649151914&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume10en_HK
dc.identifier.issue11en_HK
dc.identifier.spage2171en_HK
dc.identifier.epage2174en_HK
dc.identifier.isiWOS:000256281600021-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSun, ZN=25029021500en_HK
dc.identifier.scopusauthoridLiu, FQ=36067266700en_HK
dc.identifier.scopusauthoridChen, Y=36463185300en_HK
dc.identifier.scopusauthoridTam, PKH=7202539421en_HK
dc.identifier.scopusauthoridYang, D=7404800756en_HK

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