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Article: MicroRNAs as new players for diagnosis, prognosis, and therapeutic targets in breast cancer

TitleMicroRNAs as new players for diagnosis, prognosis, and therapeutic targets in breast cancer
Authors
KeywordsBreast Cancer
Cancer Cell
Cancer Chemotherapy
Cancer Gene Therapy
Gene Expression
Gene Targeting
Human
Prognosis
Review
Issue Date2009
PublisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/jo/
Citation
Journal Of Oncology, 2009, article no. 305420 How to Cite?
AbstractMicroRNAs are small nonprotein-coding RNAs that regulate the expressions of a wide variety of genes by sequence-specific base pairing on the 3 ′ UTR of mRNA targets resulting in mRNA degradation or inhibition of translation. Aberrant expressions of miRNAs have been linked to tumor development, metastasis, diagnosis, prognosis, and therapy response in human breast cancer. Some miRNAs have been considered to have potential clinical applications as a tool for breast cancer prognosis and therapy. Here we describe and discuss lines of evidence supporting the important relationship between miRNAs and breast cancer, and its therapeutic strategies. Copyright © 2009 Enders K. O. Ng et al.
Persistent Identifierhttp://hdl.handle.net/10722/92164
ISSN
2015 SCImago Journal Rankings: 1.190
PubMed Central ID
References

 

DC FieldValueLanguage
dc.contributor.authorKwong, Aen_HK
dc.contributor.authorNg, EKOen_HK
dc.contributor.authorWong, CLPen_HK
dc.contributor.authorMa, ESKen_HK
dc.date.accessioned2010-09-17T10:37:57Z-
dc.date.available2010-09-17T10:37:57Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Oncology, 2009, article no. 305420en_HK
dc.identifier.issn1687-8450en_HK
dc.identifier.urihttp://hdl.handle.net/10722/92164-
dc.description.abstractMicroRNAs are small nonprotein-coding RNAs that regulate the expressions of a wide variety of genes by sequence-specific base pairing on the 3 ′ UTR of mRNA targets resulting in mRNA degradation or inhibition of translation. Aberrant expressions of miRNAs have been linked to tumor development, metastasis, diagnosis, prognosis, and therapy response in human breast cancer. Some miRNAs have been considered to have potential clinical applications as a tool for breast cancer prognosis and therapy. Here we describe and discuss lines of evidence supporting the important relationship between miRNAs and breast cancer, and its therapeutic strategies. Copyright © 2009 Enders K. O. Ng et al.en_HK
dc.languageengen_HK
dc.publisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/jo/en_HK
dc.relation.ispartofJournal of Oncologyen_HK
dc.subjectBreast Canceren_HK
dc.subjectCancer Cellen_HK
dc.subjectCancer Chemotherapyen_HK
dc.subjectCancer Gene Therapyen_HK
dc.subjectGene Expressionen_HK
dc.subjectGene Targetingen_HK
dc.subjectHumanen_HK
dc.subjectPrognosisen_HK
dc.subjectReviewen_HK
dc.titleMicroRNAs as new players for diagnosis, prognosis, and therapeutic targets in breast canceren_HK
dc.typeArticleen_HK
dc.identifier.emailKwong, A: avakwong@hkucc.hku.hken_HK
dc.identifier.emailNg, EKO: ngko@hku.hken_HK
dc.identifier.authorityKwong, A=rp01734en_HK
dc.identifier.authorityNg, EKO=rp01364en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1155/2009/305420en_HK
dc.identifier.pmid19644558-
dc.identifier.pmcidPMC2716485-
dc.identifier.scopuseid_2-s2.0-68949142739en_HK
dc.identifier.hkuros163221-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68949142739&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.spagearticle no. 305420-
dc.identifier.epagearticle no. 305420-
dc.identifier.eissn1687-8469-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridKwong, A=8913654300en_HK
dc.identifier.scopusauthoridNg, EKO=21135553700en_HK
dc.identifier.scopusauthoridWong, CLP=8987839600en_HK
dc.identifier.scopusauthoridMa, ESK=7202039934en_HK
dc.identifier.citeulike10572861-

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